Torsemide Pharmaceutical API
Pharmaceutical Premium
Pharmaceutical API

Torsemide

High-purity pharmaceutical grade Torsemide API manufactured to meet stringent USP/EP specifications for diuretic medication production. Our pharmaceutical-grade Torsemide delivers exceptional quality and consistency for critical pharmaceutical applications.

  • USP/EP Compliant Grade
  • High Purity (>99.5%)
  • Loop Diuretic API
  • GMP Certified Manufacturing
  • Reliable Supply Chain
  • Complete Documentation
Request Quote Technical Support

Technical Specifications

Chemical Formula: C16H20N4O3S
CAS Number: 56211-40-6
Molecular Weight: 348.42 g/mol
Physical State: White to off-white crystalline powder
Purity (HPLC): ≥99.5% (USP/EP Grade)
Loss on Drying: ≤0.5%
Residue on Ignition: ≤0.1%
Heavy Metals (as Pb): ≤10 ppm
Related Substances: ≤0.5% (total impurities)
Particle Size: D90 ≤ 100 μm
pH (1% solution): 6.0-8.0
Solubility: Slightly soluble in water
Storage Conditions: Store at room temperature, protect from light
Shelf Life: 3 years from date of manufacture
Packaging Options: 25g, 50g, 100g pharmaceutical containers

Applications

Diuretic Therapy
Oral Tablet Formulations
Injectable Formulations
Cardiovascular Therapy
Heart Failure Treatment
Fluid Retention Management
Prescription Medications
Loop Diuretic
Cardiovascular Research
Hospital Formulations
Regulatory Submissions
Reference Standards

Industry-Specific Grades

DRAVYOM offers specialized Torsemide grades tailored for specific diuretic pharmaceutical requirements, ensuring optimal performance and regulatory compliance across diverse cardiovascular therapeutic applications.

USP Grade (United States Pharmacopeia)
Purity: ≥99.5% (HPLC) Related Substances: ≤0.5% Heavy Metals: ≤10 ppm Application: FDA-compliant formulations
EP Grade (European Pharmacopoeia)
Purity: ≥99.5% (HPLC) Loss on Drying: ≤0.5% pH: 6.0-8.0 (1% solution) Application: EU regulatory submissions
Diuretic Grade
Purity: ≥99.8% (HPLC) Diuretic Activity: Verified Bioavailability: Optimized Application: Diuretic medications
Injectable Grade
Purity: ≥99.9% (HPLC) Sterility: Compliant Endotoxin: ≤0.25 EU/mg Application: Injectable formulations

Quality Standards

DRAVYOM's Torsemide is manufactured under stringent quality control protocols, meeting international pharmaceutical standards including USP, EP specifications. Our diuretic-grade production ensures consistent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
USP/EP Grade Specifications
≥99.5% HPLC Purity
Advanced Cardiovascular Testing
Diuretic Activity Verified
Batch-to-Batch Consistency
Comprehensive COA
Pharmaceutical Grade Packaging

Advanced Chemical Properties & Performance

Pharmaceutical Grade Torsemide exhibits exceptional chemical properties essential for diuretic applications. Its loop diuretic composition and precise specification ensure reliable performance in demanding pharmaceutical formulations and cardiovascular treatment systems.

Chemical Properties
Molecular Formula: C₁₆H₂₀N₄O₃S
Molecular Weight: 348.42 g/mol
Melting Point: 163-167°C
LogP (Octanol/Water): 2.3
Physical Properties
Appearance: White to off-white crystalline powder
Solubility: Practically insoluble in water
pH (saturated solution): 7.0-8.5
Bulk Density: 0.5-0.7 g/cm³
Pharmaceutical Performance
Bioavailability: 80% (oral)
Half-life: 3.5 hours
Protein Binding: 97-99%
Mechanism: Na⁺-K⁺-2Cl⁻ transporter inhibitor
Purity Specifications
Assay (HPLC): ≥ 99.5%
Related Substances: ≤ 0.3%
Heavy Metals: ≤ 20 ppm
Residual Solvents: Within ICH limits
Stability Properties
Shelf Life: 3 years (unopened)
Photostability: Stable under normal light
Temperature Stability: Stable 15-25°C
Humidity Stability: Store ≤60% RH

Performance Characteristics

Detailed performance metrics demonstrate Pharmaceutical Grade Torsemide superiority in diuretic applications with exceptional functionality, stability, and reproducibility across diverse pharmaceutical procedures and cardiovascular protocols.

Diuretic Efficacy

Potency: High-ceiling loop diuretic

Superior fluid elimination
Duration of Action

Time: 6-8 hour therapeutic effect

Extended diuretic coverage
Bioavailability

Absorption: 80% oral bioavailability

Excellent therapeutic levels
Formulation Stability

Range: Stable in standard formulations

Consistent performance across dosage forms
Batch Uniformity

Variation: ±0.3% between production batches

Exceptional pharmaceutical grade consistency
Long-term Stability

3 years shelf life with maintained potency

Extended pharmaceutical grade integrity

Safety Information

Prescription pharmaceutical with established safety profile in cardiovascular therapy. Generally well-tolerated diuretic agent requiring electrolyte monitoring. Handle with standard laboratory precautions including appropriate protective equipment. Avoid inhalation of powder and ensure proper ventilation during processing.

Prescription Only
Cardiovascular Active
Medical Supervision

Storage & Handling

Store in original sealed containers in a cool, dry, well-ventilated area away from light and moisture. Keep containers tightly closed and protect from degradation. Use appropriate pharmaceutical handling procedures and ensure proper environmental controls for stability management.

Cool storage (15-25°C)
Low humidity (≤60% RH)
Normal light exposure acceptable
Original sealed containers

Chemical Mechanisms & Reaction Pathways

Pharmaceutical Grade Torsemide exhibits potent loop diuretic properties through pyridine-sulfonyl urea structure enabling effective fluid management with superior bioavailability and extended duration compared to furosemide.

Na-K-2Cl Inhibition

Selective inhibition of sodium-potassium-chloride cotransporter

Primary mechanism for potent diuretic action
Cardiovascular Benefits

Aldosterone antagonism and cardiovascular protection

Additional benefits beyond diuretic effects
Superior Bioavailability

Consistent 80-90% oral bioavailability

Predictable pharmacokinetics and dosing
Extended Duration

Longer half-life enables once-daily dosing

Improved patient compliance and convenience

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global pharmaceutical market access with complete API documentation supporting international standards and cardiovascular drug manufacturing validations.

USP Specifications

United States Pharmacopeia API standards compliance

EP Standards

European Pharmacopoeia specifications for pharmaceutical manufacturing

FDA Approved

FDA approved diuretic API with comprehensive cardiovascular data

EMA Approval

European Medicines Agency approval for cardiovascular applications

DMF Documentation

Drug Master File with comprehensive manufacturing and safety data

cGMP Certified

Current Good Manufacturing Practice with cardiovascular API standards

Technical Support & Value-Added Services

DRAVYOM's cardiovascular API team provides comprehensive development support, formulation optimization assistance, and regulatory services for diuretic drug manufacturing with specialized cardiology expertise.

API Development
  • Cardiovascular formulation support
  • Bioavailability enhancement studies
  • Stability optimization protocols
  • Extended-release development
Analytical Services
  • Certificate of Analysis with cardiovascular testing
  • Polymorphic form characterization
  • Impurity profiling and identification
  • Dissolution study support
Regulatory Support
  • Cardiovascular drug documentation
  • Regulatory filing assistance
  • Clinical trial support
  • Post-market surveillance
Supply Solutions
  • Consistent API supply chains
  • Temperature-controlled logistics
  • Emergency supply protocols
  • Global distribution network

Environmental Impact & Sustainability

Our Pharmaceutical Grade Torsemide production emphasizes environmental responsibility through green chemistry principles, sustainable synthetic pathways, and comprehensive environmental impact management for API manufacturing.

Green Synthesis

Optimized synthetic routes with minimal environmental impact

Solvent Recovery

Advanced solvent recycling and waste minimization

Clean Production

Energy-efficient synthesis with emission controls

Water Treatment

Advanced wastewater treatment and recycling systems

ISO 14001

Environmental management system certified production

Carbon Reduction

Continuous carbon footprint reduction initiatives

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art cardiovascular API manufacturing facility employs advanced synthetic technology and continuous monitoring systems to ensure consistent Pharmaceutical Grade Torsemide quality and therapeutic efficacy.

Production Process

Advanced multi-step synthesis with pharmaceutical-grade intermediates

Controlled synthesis for optimal purity and yield
Quality Testing

27-point pharmaceutical testing protocol including polymorphic analysis

HPLC verification and cardiovascular-specific testing
Quality Systems

cGMP compliance with cardiovascular API manufacturing standards

Continuous improvement and process validation
API Packaging

Specialized packaging with moisture and light protection

Stability maintenance and contamination prevention

Market Applications & Performance Data

Comprehensive clinical and pharmaceutical data demonstrating Pharmaceutical Grade Torsemide effectiveness across diverse cardiovascular applications with quantified therapeutic metrics and safety profiles.

Heart Failure
Efficacy: Superior fluid management vs furosemide Bioavailability: 80-90% consistent absorption Duration: 12-16 hour diuretic effect
Edema Treatment
Potency: 10-20x more potent than furosemide Electrolytes: Predictable electrolyte losses Ototoxicity: Lower risk of hearing damage
Clinical Benefits
Compliance: Once-daily dosing advantage Mortality: Improved cardiovascular outcomes Hospitalizations: Reduced readmission rates

DRAVYOM Competitive Advantages

Superior Purity

Consistently exceeds pharmacopeial specifications with optimal polymorphic control and impurity profile

Reliable Supply

Guaranteed availability with strategic inventory management and cardiovascular API expertise

API Expertise

Specialized cardiovascular API manufacturing with comprehensive development support

Quality Assurance

Enhanced testing protocols with complete documentation and regulatory compliance

Global Standards

International compliance with USP, EP, and cardiovascular drug regulations worldwide

Partnership Approach

Collaborative relationships with cardiovascular pharmaceutical companies and development support