Propylparaben
Pharmaceutical Premium
Pharmaceutical Excipient

Propylparaben

High-purity pharmaceutical Propylparaben manufactured to meet stringent USP and EP specifications for preservative applications. Our Propylparaben provides excellent antimicrobial activity with broad-spectrum effectiveness for pharmaceutical and cosmetic formulations.

  • USP/EP Pharmaceutical Grade
  • Superior Preservative Properties
  • Excellent Antimicrobial Activity
  • Enhanced Stability
  • Consistent Quality
  • Ultra-Low Impurities

Technical Specifications

Chemical Formula: C10H12O3
CAS Number: 94-13-3
EINECS Number: 202-307-7
Assay (HPLC): 99.0-101.0% (USP/EP Grade)
Physical State: White crystalline powder
Molecular Weight: 180.20 g/mol
Melting Point: 95-98°C
pH (1% solution): 4.0-6.0
Loss on Drying: ≤0.5%
Residue on Ignition: ≤0.05%
Heavy Metals: ≤10 ppm
Solubility: Slightly soluble in water
Storage Conditions: Store below 25°C, dry place
Shelf Life: 3 years from manufacture date
Packaging Options: 1kg, 5kg, 25kg bags

Applications

Antimicrobial Preservative
Ophthalmic Solutions
Liquid Formulations
Topical Preparations
Injectable Solutions
Tablet Formulations
Capsule Preparations
Parenteral Formulations
Broad-Spectrum Preservative
Oral Liquid Medicines
Cosmeceutical Products
Pharmaceutical Research

Industry-Specific Grades

DRAVYOM offers specialized Propylparaben grades tailored for specific pharmaceutical applications, ensuring optimal preservative efficacy and regulatory compliance across diverse formulation requirements.

USP Grade (United States Pharmacopoeia)
Assay: 99.0-101.0% Water Content: ≤0.5% Heavy Metals: ≤10 ppm Application: FDA approved formulations
EP Grade (European Pharmacopoeia)
Melting Point: 95-98°C Residue on Ignition: ≤0.05% Antimicrobial Activity: Verified Application: European market compliance
Injectable Grade
Sterility: Assured Endotoxins: <0.25 EU/mg Particulates: Controlled Application: Parenteral preparations
High Purity Grade
Enhanced Purity: >99.5% Low Impurities: <0.5% Superior Preservation: Verified Application: Critical formulations

Quality Standards

DRAVYOM's Propylparaben is manufactured under stringent cGMP protocols, meeting international pharmaceutical excipient standards including USP, EP, and FDA guidelines for preservative applications.

cGMP Manufacturing Standards
USP/EP Grade Specifications
99.0-101.0% HPLC Assay
Advanced Analytical Testing
Antimicrobial Activity Verified
Batch-to-Batch Consistency
Comprehensive COA Documentation
Controlled Storage & Shipping

Advanced Chemical Properties & Performance

Pharmaceutical Grade Propylparaben exhibits exceptional chemical properties essential for preservation applications. Its potent antimicrobial structure and superior stability characteristics ensure reliable performance in demanding pharmaceutical preservation systems.

Molecular Properties
Molecular Weight: 180.20 g/mol
Molecular Formula: C10H12O3
LogP (Octanol/Water): 2.04
pKa: 8.4
Physical Properties
Melting Point: 95-98°C
Appearance: White crystalline powder
Solubility (Water): 0.05% at 25°C
Bulk Density: 0.50-0.60 g/cm³
Pharmaceutical Properties
Antimicrobial Activity: Broad-spectrum preservation
pH Range: Active at pH 4.0-8.0
MIC Range: 0.01-0.1% w/w
Mechanism: Cell membrane disruption
Quality Specifications
Purity: ≥99.0%
Water Content: ≤0.5%
Free p-Hydroxybenzoic Acid: ≤0.5%
Heavy Metals: ≤10 ppm
Stability Properties
Shelf Life: 3 years (unopened)
Storage Temperature: 15-25°C
Light Sensitivity: Stable to light
Heat Stability: Stable under normal conditions

Performance Characteristics

Detailed performance metrics demonstrate Propylparaben superiority in preservation applications with exceptional antimicrobial activity, broad-spectrum efficacy, and lipophilic advantage across diverse pharmaceutical formulation systems.

Antimicrobial Activity

Potent activity against bacteria, yeasts, and molds

Broad-spectrum preservation
Lipophilic Advantage

Enhanced activity in oil-based formulations

Superior creams and ointments preservation
pH Stability

Stable preservation across wide pH range

Versatile formulation compatibility
Heat Stability

Stable under processing conditions

Manufacturing compatibility
Regulatory Status

USP/EP/FDA approved preservative

Global regulatory acceptance
Synergistic Effect

Enhanced activity with methylparaben

Optimized preservative systems

Safety Information

Generally recognized as safe (GRAS) pharmaceutical preservative requiring standard handling protocols. Handle in controlled environments with appropriate ventilation systems. Use proper personal protective equipment and follow established safety protocols for preservative materials.

GRAS Status
Standard PPE Required
Good Manufacturing Practices

Storage & Handling

Store in tightly closed containers in a cool, dry place away from direct sunlight. Maintain controlled room temperature storage and ensure protection from moisture to preserve antimicrobial efficacy and pharmaceutical quality.

Controlled room temperature (15-25°C)
Store in dry conditions
Tightly closed containers
Preserve antimicrobial activity

Chemical Mechanisms & Reaction Pathways

Propylparaben exhibits specific antimicrobial mechanisms through cell membrane disruption and enzyme inhibition pathways essential for pharmaceutical preservation. Its molecular structure enables broad-spectrum antimicrobial activity with predictable preservative efficacy.

Antimicrobial Action

Cell membrane disruption and enzyme inhibition mechanisms

Broad-spectrum antimicrobial activity
Metabolic Pathways

Hydrolysis to p-hydroxybenzoic acid and n-propanol

Predictable clearance mechanisms
Formulation Stability

Chemical stability across pH ranges and temperatures

Preservative efficacy maintenance
Synergistic Effects

Enhanced antimicrobial activity with methylparaben

Optimized preservative systems

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global pharmaceutical access with complete documentation packages supporting international drug development and manufacturing standards.

USP Specifications

United States Pharmacopeia pharmaceutical standards compliance

EP Standards

European Pharmacopoeia specifications for pharmaceutical quality

ICH Guidelines

International Conference on Harmonization standards compliance

GMP Certification

Good Manufacturing Practices certified production facility

DMF Support

Drug Master File documentation for regulatory submissions

CEP Available

Certificate of Suitability to European Pharmacopoeia monographs

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical development team provides comprehensive formulation support, regulatory assistance, and technical services to optimize pharmaceutical performance in your specific drug development applications.

Formulation Development
  • Dosage form optimization support
  • Stability testing guidance
  • Bioavailability enhancement
  • Custom formulation development
Analytical Services
  • Method development and validation
  • Impurity profiling and identification
  • Stability indicating methods
  • Dissolution testing support
Regulatory Support
  • Regulatory submission assistance
  • DMF preparation and maintenance
  • Pharmacovigilance support
  • Global registration strategy
Supply Solutions
  • Pharmaceutical supply chain management
  • Cold chain logistics
  • Custom packaging solutions
  • Global distribution network

Environmental Impact & Sustainability

Our pharmaceutical production emphasizes environmental responsibility through sustainable manufacturing practices, green chemistry principles, and comprehensive environmental impact management for pharmaceutical operations.

Green Chemistry

Sustainable synthetic routes with minimal environmental impact

Water Management

Advanced wastewater treatment and recycling systems

Clean Production

Energy-efficient synthesis with emission controls

Safe Disposal

Comprehensive pharmaceutical waste management protocols

ISO 14001

Environmental management system certified production

Sustainable Packaging

Recyclable pharmaceutical packaging solutions

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art pharmaceutical manufacturing facility employs advanced synthesis technology and continuous monitoring systems to ensure consistent pharmaceutical quality and performance across all production batches.

Production Process

Advanced synthesis and purification in GMP-controlled clean-room environment

Multi-stage purification for pharmaceutical grade quality
Quality Testing

Comprehensive testing protocol including purity, potency, and impurity profiling

HPLC, GC-MS, and spectroscopic analysis
Quality Systems

ISO 9001:2015 and GMP quality management systems

Continuous improvement and validation protocols
Packaging Control

Pharmaceutical-grade packaging with controlled atmosphere

Contamination prevention and stability protection

Market Applications & Performance Data

Comprehensive pharmaceutical development data demonstrating effectiveness across diverse therapeutic applications with quantified performance metrics and clinical validation support.

Pharmaceutical Development
Formulation Success: 95+ formulations developed Regulatory Approvals: 100+ successful submissions Quality Consistency: 99.9% batch compliance
Research Applications
Clinical Studies: 200+ supported trials Publication Support: 150+ peer-reviewed papers Innovation: Custom API development
Commercial Manufacturing
Scale-up Success: 100% process transfers Supply Reliability: 99.8% on-time delivery Cost Optimization: 25% average cost reduction

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

Consistently exceeds pharmacopeial specifications with superior purity and pharmaceutical performance

Reliable Supply

Guaranteed pharmaceutical availability with strategic inventory and GMP production scheduling

Development Expertise

Dedicated pharmaceutical development team provides formulation and regulatory support

Regulatory Assurance

Complete regulatory packages with DMF support and global registration assistance

Global Standards

International compliance with USP, EP, and ICH standards for worldwide market access

Partnership Approach

Collaborative relationships with pharmaceutical companies and custom development services