Propylene Glycol
Pharmaceutical Premium
Pharmaceutical Excipient

Propylene Glycol

High-purity pharmaceutical Propylene Glycol manufactured to meet stringent USP and EP specifications for pharmaceutical applications. Our Propylene Glycol provides excellent solvent and humectant properties for various pharmaceutical formulations and topical applications.

  • USP/EP Pharmaceutical Grade
  • Superior Solvent Properties
  • Excellent Humectant Properties
  • Enhanced Stability
  • Consistent Quality
  • Ultra-Low Impurities
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Technical Specifications

Chemical Formula: C3H8O2
CAS Number: 57-55-6
EINECS Number: 200-338-0
Assay: 99.5-100.5% (USP/EP Grade)
Physical State: Clear, colorless, viscous liquid
Molecular Weight: 76.09 g/mol
Specific Gravity: 1.035-1.040 at 20°C
Refractive Index: 1.431-1.433 at 20°C
Water Content: ≤0.2%
Residue on Ignition: ≤0.005%
Heavy Metals: ≤5 ppm
Solubility: Miscible with water and ethanol
Storage Conditions: Store below 25°C, protect from light
Shelf Life: 3 years from manufacture date
Packaging Options: 1kg, 5kg, 25kg containers

Applications

Pharmaceutical Solvent
Humectant Agent
Topical Preparations
Ophthalmic Solutions
Injectable Formulations
Soft Gel Capsules
Oral Liquid Medicines
Solubilizing Agent
Preservative System
Viscosity Modifier
Cosmeceutical Products
Pharmaceutical Research

Industry-Specific Grades

DRAVYOM offers specialized Propylene Glycol grades tailored for specific pharmaceutical applications, ensuring optimal solvent and humectant properties with regulatory compliance across diverse formulation requirements.

USP Grade (United States Pharmacopoeia)
Assay: 99.5-100.5% Water Content: ≤0.2% Heavy Metals: ≤5 ppm Application: FDA approved formulations
EP Grade (European Pharmacopoeia)
Specific Gravity: 1.035-1.040 Refractive Index: 1.431-1.433 Residue on Ignition: ≤0.005% Application: European market compliance
Injectable Grade
Sterility: Assured Endotoxins: <0.25 EU/ml Particulates: Controlled Application: Parenteral preparations
High Purity Grade
Enhanced Purity: >99.8% Low Impurities: <0.2% Superior Solvent Properties: Verified Application: Critical formulations

Quality Standards

DRAVYOM's Propylene Glycol is manufactured under stringent cGMP protocols, meeting international pharmaceutical excipient standards including USP, EP, and FDA guidelines for solvent applications.

cGMP Manufacturing Standards
USP/EP Grade Specifications
99.5-100.5% Assay
Advanced Analytical Testing
Solvent Properties Verified
Batch-to-Batch Consistency
Comprehensive COA Documentation
Controlled Storage & Shipping

Advanced Chemical Properties & Performance

Propylene Glycol exhibits exceptional solvent properties essential for pharmaceutical applications. Its ultra-pure composition and precise molecular structure ensure reliable performance in demanding oral and topical formulations.

Molecular Properties
Molecular Weight: 76.09 g/mol
LogP: -0.92
pKa: 14.9
Bioavailability: Non-absorbed excipient
Physical Properties
Boiling Point: 188.2°C
Solubility (Water): Miscible
Crystalline Form: Clear liquid
Hygroscopicity: Hygroscopic
Pharmaceutical Performance
Viscosity: 52 cP at 20°C
Solvent Power: Excellent
Selectivity: Co-solvent/humectant
Stability: Stable
Purity Specifications
Assay: 99.5-100.5%
Water Content: ≤0.2%
Heavy Metals: ≤5 ppm
Microbial Limits: USP compliant
Stability Properties
Shelf Life: 3 years (unopened)
Light Sensitivity: Not light sensitive
Temperature Stability: Room temperature stable
pH Stability: Stable pH 3-11

Performance Characteristics

Detailed performance metrics demonstrate Propylene Glycol superiority in pharmaceutical applications with exceptional solvent properties, miscibility, and reproducibility across diverse pharmaceutical formulations.

Solvent Power

Viscosity: 52 cP excellent flow

Superior processing characteristics
Miscibility

Water: Complete miscibility

Excellent co-solvent properties
Stability

Liquid state: >3 years stability

Long-term pharmaceutical integrity
Thermal Stability

Working range: 15-40°C processing

Stable during formulation
Batch Reproducibility

Variation: ±0.2% between batches

Consistent lot-to-lot performance
Shelf Stability

3 years under proper storage conditions

Extended pharmaceutical grade integrity

Safety Information

Pharmaceutical grade excipient requiring standard handling. Handle with appropriate protective equipment in controlled environments. Avoid skin contact and inhalation. Follow cGMP guidelines for pharmaceutical excipients and ensure proper waste disposal procedures.

Pharmaceutical Excipient
Avoid Skin Contact
Avoid Inhalation

Storage & Handling

Store in original sealed containers in a cool, dry, well-ventilated area away from moisture. Keep containers tightly closed and protect from humidity. Use appropriate containment measures for pharmaceutical excipient handling.

Room temperature storage (15-25°C)
Protect from moisture
Original sealed containers
Pharmaceutical containment required

Chemical Mechanisms & Reaction Pathways

Propylene Glycol exhibits specific solvent and pharmaceutical excipient mechanisms essential for drug formulation and delivery. Its molecular structure enables effective solubilization and stabilization properties with predictable pharmaceutical performance responses.

Solvent Properties

Excellent solubilization of both hydrophilic and lipophilic compounds

Enhanced drug dissolution
Stabilization Effects

Prevents crystallization and maintains formulation stability

Extended shelf life
Humectant Action

Maintains moisture content in pharmaceutical formulations

Improved formulation integrity
Biocompatibility

Excellent tolerability for pharmaceutical applications

Enhanced safety profile

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global pharmaceutical access with complete documentation packages supporting international drug development and manufacturing standards.

USP Specifications

United States Pharmacopeia pharmaceutical standards compliance

EP Standards

European Pharmacopoeia specifications for pharmaceutical quality

ICH Guidelines

International Conference on Harmonization standards compliance

GMP Certification

Good Manufacturing Practices certified production facility

DMF Support

Drug Master File documentation for regulatory submissions

CEP Available

Certificate of Suitability to European Pharmacopoeia monographs

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical development team provides comprehensive formulation support, regulatory assistance, and technical services to optimize pharmaceutical performance in your specific drug development applications.

Formulation Development
  • Dosage form optimization support
  • Stability testing guidance
  • Bioavailability enhancement
  • Custom formulation development
Analytical Services
  • Method development and validation
  • Impurity profiling and identification
  • Stability indicating methods
  • Dissolution testing support
Regulatory Support
  • Regulatory submission assistance
  • DMF preparation and maintenance
  • Pharmacovigilance support
  • Global registration strategy
Supply Solutions
  • Pharmaceutical supply chain management
  • Cold chain logistics
  • Custom packaging solutions
  • Global distribution network

Environmental Impact & Sustainability

Our pharmaceutical production emphasizes environmental responsibility through sustainable manufacturing practices, green chemistry principles, and comprehensive environmental impact management for pharmaceutical operations.

Green Chemistry

Sustainable synthetic routes with minimal environmental impact

Water Management

Advanced wastewater treatment and recycling systems

Clean Production

Energy-efficient synthesis with emission controls

Safe Disposal

Comprehensive pharmaceutical waste management protocols

ISO 14001

Environmental management system certified production

Sustainable Packaging

Recyclable pharmaceutical packaging solutions

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art pharmaceutical manufacturing facility employs advanced synthesis technology and continuous monitoring systems to ensure consistent pharmaceutical quality and performance across all production batches.

Production Process

Advanced synthesis and purification in GMP-controlled clean-room environment

Multi-stage purification for pharmaceutical grade quality
Quality Testing

Comprehensive testing protocol including purity, potency, and impurity profiling

HPLC, GC-MS, and spectroscopic analysis
Quality Systems

ISO 9001:2015 and GMP quality management systems

Continuous improvement and validation protocols
Packaging Control

Pharmaceutical-grade packaging with controlled atmosphere

Contamination prevention and stability protection

Market Applications & Performance Data

Comprehensive pharmaceutical development data demonstrating effectiveness across diverse therapeutic applications with quantified performance metrics and clinical validation support.

Pharmaceutical Development
Formulation Success: 95+ formulations developed Regulatory Approvals: 100+ successful submissions Quality Consistency: 99.9% batch compliance
Research Applications
Clinical Studies: 200+ supported trials Publication Support: 150+ peer-reviewed papers Innovation: Custom API development
Commercial Manufacturing
Scale-up Success: 100% process transfers Supply Reliability: 99.8% on-time delivery Cost Optimization: 25% average cost reduction

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

Consistently exceeds pharmacopeial specifications with superior purity and pharmaceutical performance

Reliable Supply

Guaranteed pharmaceutical availability with strategic inventory and GMP production scheduling

Development Expertise

Dedicated pharmaceutical development team provides formulation and regulatory support

Regulatory Assurance

Complete regulatory packages with DMF support and global registration assistance

Global Standards

International compliance with USP, EP, and ICH standards for worldwide market access

Partnership Approach

Collaborative relationships with pharmaceutical companies and custom development services