Povidone K30 (PVP K30) - Pharmaceutical Ingredient
Pharmaceutical Binder
Pharmaceutical Ingredient

Povidone K30 (PVP K30)

Premium pharmaceutical-grade povidone K30 engineered for demanding drug formulation applications including tablet binding, film coating, and drug solubilization. Our high-performance excipient delivers exceptional binding efficiency, consistent performance, and reliable supply for critical pharmaceutical manufacturing processes requiring superior tablet properties with stringent regulatory compliance standards.

  • USP/EP/IP Grade Compliance
  • K-Value 27.0-32.4
  • 44,000-54,000 Da MW
  • Superior Binding Properties
  • Film Coating Compatible
  • Drug Solubilization
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Technical Specifications

Chemical Name: Povidone K30 (PVP K30)
CAS Number: 9003-39-8
K-Value: 27.0-32.4
Average Molecular Weight: 44,000-54,000 Da
Physical State: White to cream hygroscopic powder
Loss on Drying: ≤ 5.0%
Residue on Ignition: ≤ 0.1%
Heavy Metals (as Pb): ≤ 10 ppm
pH (5% solution): 3.0-7.0
Nitrogen Content: 11.5-12.8%
Aldehydes (as Acetaldehyde): ≤ 500 ppm
Peroxides (as H₂O₂): ≤ 400 ppm
Microbial Limits: ≤ 1000 CFU/g
Shelf Life: 5 years
Packaging Options: 25kg fiber drums

Applications

Tablet Binder & Disintegrant
Film Coating Agent
Stabilizer & Suspending Agent
Ophthalmic Solutions
Parenteral Formulations
Capsule Manufacturing

Industry-Specific Grades

DRAVYOM offers specialized PVP K30 grades tailored for different pharmaceutical formulation requirements, ensuring optimal performance and regulatory compliance.

Tablet Grade
Binding Properties: Excellent Disintegration: Controlled Granulation: Enhanced Application: Solid dosage forms
Coating Grade
Film Forming: Superior Adhesion: Excellent Flexibility: High Application: Film coating
Injectable Grade
Endotoxin: ≤ 2.5 EU/g Sterility: Assured Biocompatibility: High Application: Parenteral use
Standard Grade
USP/EP/IP: Compliant Cost Effective: Optimized Versatile: Multi-purpose Application: General formulations

Quality Standards

DRAVYOM's Povidone K30 is manufactured under cGMP conditions, meeting international pharmaceutical standards for excipient applications.

cGMP Certified Manufacturing
Pharmaceutical Grade Standards
K-Value 27.0-32.4
USP/EP/IP Compliant
Complete Testing Protocol
Injectable Grade Available
Certificate of Analysis
Pharmaceutical Support

Advanced Chemical Properties & Performance

Pharmaceutical Grade Povidone K30 exhibits excellent binding and film-forming properties essential for tablet coating and drug delivery applications. Its controlled molecular weight and superior solubility ensure consistent performance in pharmaceutical formulations.

Pharmaceutical Properties
K-Value: 27.0-32.4 (USP)
Molecular Weight: 44,000-54,000 Da
pH (5% solution): 3.0-7.0
Water Solubility: Freely soluble
Physical Properties
Glass Transition Temp: 150-180°C
Bulk Density: 0.3-0.5 g/cm³
Loss on Drying: ≤ 5.0%
Particle Size: Fine powder
Formulation Performance
Binding Capacity: Excellent tablet cohesion
Film Formation: Clear, flexible films
Solubilization: Enhanced drug dissolution
Compatibility: Wide API compatibility
Purity Specifications
Assay (PVP): ≥ 95.0%
Heavy Metals: ≤ 10 ppm
Residue on Ignition: ≤ 0.1%
Aldehyde Content: ≤ 500 ppm
Stability Properties
Shelf Life: 5 years (unopened)
Thermal Stability: Stable up to 150°C
Hygroscopic Nature: Absorbs moisture readily
pH Stability: Stable pH 1-14

Performance Characteristics

Performance metrics demonstrate Pharmaceutical Grade Povidone K30 excellence in binding, coating, and solubilization applications with superior molecular weight control, consistent film properties, and reliable performance across diverse pharmaceutical formulations.

Binding Strength

Tablet hardness: 10-15 kP typical range

Superior tablet cohesion
Film Quality

Coating thickness: 2-5% weight gain typical

Uniform film formation
Dissolution Enhancement

Bioavailability: 15-30% improvement typical

Enhanced drug release
Weight Uniformity

Tablet weight variation: ±1.5% typical

Excellent processability
Batch Consistency

K-value variation: ±2.5% between batches

Reliable pharmaceutical performance
Stability

Shelf life: 5 years under proper storage

Extended product lifecycle

Safety Information

Povidone K30 is generally recognized as safe (GRAS) for pharmaceutical use. Use standard Good Manufacturing Practices (GMP), avoid dust inhalation, and wear appropriate protective equipment during handling. Ensure proper dust control systems in manufacturing areas.

Pharmaceutical Grade
Dust Control
GRAS Status

Storage & Handling

Store in original containers in a cool, dry place with controlled humidity. Protect from moisture and ensure proper sealing after use. Maintain GMP storage conditions and use first-in-first-out inventory rotation. Avoid contamination with other materials.

Store at 15-30°C
Relative humidity <60%
Original packaging preferred
GMP storage conditions

Chemical Mechanisms & Reaction Pathways

Povidone K30 exhibits excellent binding and film-forming properties through hydrogen bonding and chain entanglement, enabling optimal tablet cohesion and controlled drug release with predictable pharmaceutical performance.

Binding Mechanism

Polymer chain interaction and hydrogen bonding for tablet binding applications

Essential for wet granulation processes
Film Formation

Continuous film formation for coating and encapsulation applications

Critical for controlled release systems
Solubilization

Enhanced drug solubility through complexation and micelle formation

Enables improved bioavailability
Molecular Weight

Optimal molecular weight for pharmaceutical processing and performance

Important for binding strength and dissolution

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures pharmaceutical-grade PVP K30 meets international pharmacopeial standards with complete documentation packages supporting drug development and regulatory submissions.

Pharmacopeial Standards

USP, EP, and JP compliance for pharmaceutical excipient applications

GMP Compliance

Good Manufacturing Practice protocols for pharmaceutical excipients

Safety Documentation

Complete toxicological data and pharmaceutical safety profiles

International Registration

DMF filings and excipient master file documentation

Quality Documentation

Certificates of analysis and pharmaceutical quality certificates

Supply Chain

GMP-compliant transportation and pharmaceutical logistics

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical excipient support team provides comprehensive formulation guidance, technical assistance, and regulatory support to optimize PVP K30 applications in pharmaceutical manufacturing.

Formulation Support
  • Wet granulation optimization
  • Tablet binding enhancement
  • Film coating development
  • Solubilization strategies
Technical Services
  • Molecular weight verification
  • Binding strength testing
  • Stability testing guidance
  • Process optimization support
Quality Services
  • GMP compliance consultation
  • Method validation support
  • Quality system documentation
  • Pharmacopeial testing protocols
Supply Solutions
  • Pharmaceutical-grade packaging
  • Just-in-time delivery programs
  • Custom molecular weight grades
  • Inventory management services

Environmental Impact & Sustainability

Our pharmaceutical PVP K30 production emphasizes environmental responsibility through sustainable sourcing, energy-efficient manufacturing, and comprehensive environmental impact management for sustainable pharmaceutical development.

Sustainable Sourcing

Renewable monomer sources with sustainable chemical practices

Green Chemistry

Environmentally friendly polymerization processes

Clean Production

Energy-efficient manufacturing with emission controls

Waste Management

Pharmaceutical waste minimization and recycling programs

Environmental Standards

ISO 14001 environmental management system compliance

Packaging Solutions

Recyclable pharmaceutical packaging and container programs

Manufacturing Excellence & Quality Control

DRAVYOM's pharmaceutical PVP K30 manufacturing facility employs advanced polymerization technology and quality systems to ensure consistent pharmaceutical-grade quality and performance across all production batches.

Advanced Polymerization

Controlled polymerization processes for consistent molecular weight distribution

Optimal K-value and purity control
Quality Testing

Comprehensive testing including K-value, viscosity, and pharmaceutical properties

USP/EP method validation and compliance
GMP Systems

cGMP compliance with pharmaceutical excipient quality systems

FDA and EMA inspection-ready facilities
Pharmaceutical Packaging

Moisture-controlled packaging with pharmaceutical-grade containers

Stability-optimized packaging systems

Market Applications & Performance Data

Comprehensive pharmaceutical data demonstrating PVP K30 effectiveness across pharmaceutical applications with validated performance metrics and pharmaceutical industry adoption for binding and coating.

Tablet Binding
Binding Efficiency: 96% tablet hardness target achievement Performance: Consistent compression properties Customer Satisfaction: 95% pharmaceutical approval
Film Coating
Film Quality: Superior coating properties Process Efficiency: 30% coating time reduction Market Penetration: 50% film coating segment
Solubilization
Solubility Enhancement: 400% improvement in drug dissolution Cost Effectiveness: 25% formulation cost savings Bioavailability: 35% improvement in drug absorption

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

cGMP-compliant PVP manufacturing with pharmaceutical regulatory expertise and formulation support

Polymer Innovation

Advanced polymerization technology with custom K-value grades and purity optimization

Quality Assurance

Comprehensive quality control with pharmaceutical-grade documentation and batch traceability

Reliable Supply

Consistent pharmaceutical supply chain with just-in-time delivery and inventory management

Regulatory Support

DMF filing assistance with regulatory submission support and global compliance expertise

Partnership Approach

Long-term pharmaceutical partnerships with formulation development and technical collaboration