Nicotinamide Riboside Chloride USP/EP
Pharmaceutical USP/EP
Pharmaceutical API

Nicotinamide Riboside Chloride USP/EP

High-purity pharmaceutical grade Nicotinamide Riboside Chloride manufactured under stringent cGMP conditions. This NAD+ precursor API is essential for cellular energy metabolism and longevity applications, particularly in anti-aging supplementation, providing reliable quality and regulatory compliance.

  • USP/EP Grade Pharmaceutical API
  • cGMP Manufacturing Standards
  • ≥98.0% Purity (HPLC)
  • Comprehensive COA Documentation
  • NAD+ Precursor for Cellular Energy
  • Regulatory Compliance Ready
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Technical Specifications

Chemical Formula: C11H15N2O5·Cl
CAS Number: 23111-00-4
EINECS Number: 245-417-5
Purity (HPLC): ≥98.0% (USP/EP Grade)
Physical State: White to off-white hygroscopic powder
Molecular Weight: 290.70 g/mol
Melting Point: 140-144°C (with decomposition)
pH (1% solution): 5.5-7.5
Loss on Drying: ≤1.0%
Residue on Ignition: ≤0.2%
Heavy Metals: ≤10 ppm
Solubility: Freely soluble in water
Storage Conditions: Store at 2-8°C, dry place
Shelf Life: 2 years from manufacture date
Packaging Options: 1kg, 5kg, 25kg containers

Applications

NAD+ Supplementation
Anti-aging Products
Cellular Energy Metabolism
Neuroprotection
Longevity Research
Nutraceutical Supplements
Cardiovascular Health
Antioxidant Formulations
Muscle Health Support
Wellness Products
Clinical Research
Pharmaceutical Development

Industry-Specific Grades

DRAVYOM offers specialized Nicotinamide Riboside Chloride grades tailored for specific longevity and anti-aging applications, ensuring optimal bioavailability and regulatory compliance across diverse supplement formulations.

USP Grade (United States Pharmacopoeia)
Purity: ≥98.0% Water Content: ≤1.0% Heavy Metals: ≤10 ppm Application: Pharmaceutical formulations
EP Grade (European Pharmacopoeia)
Purity: ≥98.0% Related Substances: ≤2.0% Residual Solvents: EP limits Application: European market compliance
Nutraceutical Grade
Purity: ≥97.0% Dietary Safety: Verified Stability: Enhanced Application: Dietary supplements
Research Grade
Purity: ≥95.0% NAD+ Activity: Verified Bioavailability: Tested Application: Longevity research

Quality Standards

DRAVYOM's Nicotinamide Riboside Chloride is manufactured under stringent cGMP protocols, meeting international nutraceutical standards including USP, EP, and FDA guidelines for longevity and anti-aging applications.

cGMP Manufacturing Standards
USP/EP Grade Specifications
≥98.0% HPLC Purity
Advanced NAD+ Activity Testing
Cellular Benefits Verified
Stability & Bioavailability
Comprehensive COA Documentation
Cold Chain Storage & Shipping

Advanced Chemical Properties & Performance

Nicotinamide Riboside Chloride exhibits exceptional NAD+ precursor properties essential for longevity applications. Its ultra-pure composition and precise molecular structure ensure reliable performance in demanding nutraceutical and anti-aging formulations.

Molecular Properties
Molecular Weight: 290.70 g/mol
LogP: -2.1
pKa: 3.4
Bioavailability: 88%
Physical Properties
Melting Point: 174-178°C
Solubility (Water): >50 mg/mL
Crystalline Form: Stable polymorph
Hygroscopicity: Slightly hygroscopic
Biological Performance
NAD+ Conversion: 95% cellular uptake
Cellular Activity: Enhanced mitochondrial function
Biomarker Response: Verified NAD+ elevation
Stability: Stable in physiological conditions
Purity Specifications
Assay: ≥98.0%
Related Substances: ≤1.0%
Heavy Metals: ≤10 ppm
Residual Solvents: ICH Q3C compliant
Stability Properties
Shelf Life: 3 years (unopened)
Light Sensitivity: Protect from light
Temperature Stability: Stable at room temperature
pH Stability: Stable pH 3-7

Performance Characteristics

Detailed performance metrics demonstrate Nicotinamide Riboside Chloride superiority in nutraceutical applications with exceptional NAD+ boosting capacity, bioavailability, and reproducibility across diverse longevity formulations.

NAD+ Elevation

Increase: 2.7x baseline NAD+ levels

Significant cellular NAD+ boost
Bioavailability

Oral: 88% absolute bioavailability

Superior absorption profile
Cellular Uptake

Efficiency: 95% cellular conversion

Excellent bioactivity
Thermal Stability

Working range: 15-40°C processing

Stable during formulation
Batch Reproducibility

Variation: ±1% between batches

Consistent lot-to-lot performance
Shelf Stability

3 years under proper storage conditions

Extended nutraceutical grade integrity

Safety Information

Generally recognized as safe (GRAS) for dietary supplement use. Well-tolerated nutraceutical ingredient with excellent safety profile. Handle with standard pharmaceutical manufacturing precautions including appropriate protective equipment and dust control measures.

GRAS Status
Well-Tolerated
Excellent Safety Profile

Storage & Handling

Store in original sealed containers in a cool, dry, well-ventilated area away from light and moisture. Keep containers tightly closed and protect from direct sunlight. Use appropriate handling measures for nutraceutical ingredients.

Cool storage (15-25°C)
Protect from light
Original sealed containers
Low humidity environment

Chemical Mechanisms & Reaction Pathways

Nicotinamide riboside chloride represents an advanced NAD+ precursor that bypasses conventional biosynthetic pathways, providing enhanced cellular energy metabolism and longevity benefits through direct NAD+ boosting mechanisms.

NAD+ Biosynthesis

Direct conversion to NAD+ via salvage pathway enzymes

Superior bioavailability over niacin and niacinamide
Cellular Energy

Enhanced mitochondrial function and ATP production

Improved cellular energy metabolism
Longevity Pathways

Activation of sirtuin proteins and DNA repair mechanisms

Anti-aging and neuroprotective effects
Pharmacokinetic Profile

Excellent oral bioavailability with tissue distribution

Optimized therapeutic dosing

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global pharmaceutical acceptance with complete documentation packages supporting international drug development and manufacturing requirements.

USP Specifications

United States Pharmacopeia pharmaceutical grade compliance

EP Standards

European Pharmacopoeia specifications and testing protocols

ICH Guidelines

International harmonized pharmaceutical development standards

Global Regulatory

Multi-regional pharmaceutical registration support

DMF Support

Drug Master File preparation and regulatory submission

GMP Compliance

Good Manufacturing Practice certified production

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical development team provides comprehensive formulation support, analytical method development, and regulatory assistance to optimize Nicotinamide Riboside Chloride performance in pharmaceutical applications.

Formulation Development
  • Stability-enhanced formulations
  • Bioavailability optimization
  • Capsule and tablet development
  • Targeted delivery systems
Analytical Services
  • Method validation and transfer
  • Impurity profiling and identification
  • Stability testing programs
  • Bioanalytical support
Regulatory Support
  • Regulatory strategy development
  • Documentation preparation
  • Regulatory submission support
  • Global compliance guidance
Supply Solutions
  • Reliable supply chain management
  • Flexible packaging options
  • Emergency supply arrangements
  • Global distribution network

Environmental Impact & Sustainability

Our Nicotinamide Riboside Chloride production emphasizes environmental responsibility through sustainable pharmaceutical manufacturing practices, waste minimization, and comprehensive environmental impact management.

Green Chemistry

Environmentally conscious synthesis with minimal waste

Water Management

Advanced wastewater treatment and recycling systems

Energy Efficiency

Optimized manufacturing processes with reduced energy consumption

Waste Reduction

Comprehensive waste minimization and disposal protocols

ISO 14001

Environmental management system certified production

Carbon Footprint

Reduced environmental impact through sustainable practices

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art pharmaceutical manufacturing facility employs advanced synthesis technology and continuous monitoring systems to ensure consistent Nicotinamide Riboside Chloride quality and performance across all production batches.

GMP Production

Good Manufacturing Practice certified facility with controlled environments

Pharmaceutical-grade production standards
Quality Testing

Comprehensive analytical testing including purity and stability

HPLC, LC-MS, and advanced analytical methods
Quality Systems

ISO 9001:2015 quality management with pharmaceutical compliance

Continuous improvement and validation protocols
Packaging Control

Controlled atmosphere packaging with moisture protection

Stability maintenance and protection systems

Market Applications & Performance Data

Comprehensive pharmaceutical data demonstrating Nicotinamide Riboside Chloride effectiveness across diverse therapeutic applications with quantified performance metrics and clinical validation.

Pharmaceutical Manufacturing
Bioavailability: Superior NAD+ elevation Stability: Enhanced formulation stability Purity: >99% pharmaceutical grade
Drug Development
Formulation Support: Advanced delivery systems Regulatory Success: Global approvals achieved Innovation: Longevity applications
Clinical Applications
Efficacy: Proven NAD+ boosting effects Safety: Excellent tolerance profile Convenience: Oral administration

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

Consistently exceeds specifications with pharmaceutical-grade quality and superior NAD+ boosting performance

Reliable Supply

Guaranteed availability with strategic inventory management and pharmaceutical-grade production

Development Expertise

Dedicated pharmaceutical team provides formulation development and regulatory support

Quality Assurance

Comprehensive documentation with pharmaceutical-grade certificates and regulatory compliance

Global Standards

International compliance with USP, EP, and ICH guidelines for worldwide acceptance

Partnership Approach

Collaborative relationships with pharmaceutical companies and custom development services