Methylparaben
Pharmaceutical Premium
Pharmaceutical Excipient

Methylparaben

High-purity pharmaceutical Methylparaben manufactured to meet stringent USP and EP specifications for preservative applications. Our Methylparaben provides excellent antimicrobial activity and stability for various pharmaceutical formulations and cosmetic applications.

  • USP/EP Pharmaceutical Grade
  • Superior Preservative Properties
  • Excellent Antimicrobial Activity
  • Enhanced Stability
  • Consistent Quality
  • Ultra-Low Impurities
Request Quote Technical Support

Technical Specifications

Chemical Formula: C8H8O3
CAS Number: 99-76-3
EINECS Number: 202-785-7
Molecular Weight: 152.15 g/mol
Physical State: White crystalline powder
Purity (HPLC): ≥99.0% (USP/EP Grade)
Melting Point: 125-128°C
pH (1% solution): 3.0-4.0
Loss on Drying: ≤0.5%
Residue on Ignition: ≤0.05%
Heavy Metals (as Pb): ≤10 ppm
Chloride: ≤50 ppm
Storage Conditions: Store in cool, dry place
Shelf Life: 3 years from date of manufacture
Packaging Options: 25kg drums, 50kg containers

Applications

Pharmaceutical Preservative
Ophthalmic Preparations
Injectable Formulations
Topical Applications
Oral Suspensions
Hospital Pharmacy
Pharmaceutical Manufacturing
Antimicrobial Activity
Formulation Research
Clinical Formulations
Regulatory Submissions
Reference Standards

Industry-Specific Grades

DRAVYOM offers specialized Methylparaben grades tailored for specific pharmaceutical preservative requirements, ensuring optimal performance and regulatory compliance across diverse pharmaceutical formulation applications.

USP Grade (United States Pharmacopeia)
Purity: ≥99.0% (HPLC) Loss on Drying: ≤0.5% Heavy Metals: ≤10 ppm Application: FDA-compliant formulations
EP Grade (European Pharmacopoeia)
Purity: ≥99.0% (HPLC) Chloride: ≤50 ppm Residue on Ignition: ≤0.05% Application: EU regulatory submissions
Pharmaceutical Research Grade
Purity: ≥99.5% (HPLC) Enhanced antimicrobial activity Low endotoxin levels Application: Preservative research
Reference Standard Grade
Purity: ≥99.8% (HPLC) Certified Analysis: COA included Traceability: NIST traceable Application: Analytical standards

Quality Standards

DRAVYOM's Methylparaben is manufactured under stringent quality control protocols, meeting international pharmaceutical standards including USP, EP, and cGMP specifications. Our pharmaceutical-grade production ensures consistent performance and regulatory compliance.

cGMP Certified Manufacturing
USP/EP Grade Specifications
≥99.0% HPLC Purity
Advanced Analytical Testing
Superior Preservative Activity
Batch-to-Batch Consistency
Comprehensive Certificate of Analysis
Controlled Storage Conditions

Advanced Chemical Properties & Performance

Methylparaben exhibits exceptional pharmaceutical properties essential for preservative applications. Its ultra-pure composition and precise molecular structure ensure reliable performance in demanding pharmaceutical formulations and cosmetic preparations.

Pharmaceutical Properties
Molecular Weight: 152.15 g/mol
Solubility (Water): Slightly soluble
Partition Coefficient: LogP = 1.96
Antimicrobial Activity: Broad spectrum efficacy
Physical Properties
Melting Point: 125-128°C
Appearance: White crystalline powder
Crystalline Form: Stable polymorphic form
Bulk Density: 0.40-0.60 g/mL
Formulation Performance
Dissolution Rate: ≥80% in 30 minutes
Compatibility: Excellent with most excipients
pH Stability: Stable pH 4-8
Flow Properties: Good to excellent
Purity Specifications
Total Impurities: ≤1.0%
Related Substances: ≤0.5% individual
Heavy Metals: ≤10 ppm
Residual Solvents: ICH Q3C compliant
Stability Properties
Shelf Life: 5 years (unopened)
Light Sensitivity: Stable to light
Temperature Stability: Stable 15-30°C
Humidity Sensitivity: Store below 65% RH

Performance Characteristics

Detailed performance metrics demonstrate Methylparaben superiority in pharmaceutical applications with exceptional efficacy, stability, and reproducibility across diverse formulation types and preservative protocols.

Preservative Performance

Antimicrobial Activity: Broad spectrum efficacy

Excellent preservative protection
Dissolution Rate

Release: ≥80% in 30 minutes

Consistent drug release profile
Analytical Performance

Purity: ≥99.0% HPLC

Superior analytical precision
Stability Performance

Shelf life: 5 years under proper storage

Extended pharmaceutical integrity
Batch Reproducibility

Variation: ±1.0% between batches

Exceptional lot-to-lot consistency
Processing Performance

Compatibility: Excellent with most excipients

Superior manufacturing efficiency

Safety Information

Pharmaceutical grade preservative material requiring appropriate handling procedures. Use standard pharmaceutical safety protocols including proper ventilation, protective equipment, and trained personnel. Follow all applicable regulatory guidelines for pharmaceutical manufacturing and handling.

Preservative Material
Trained Personnel Required
cGMP Compliance

Storage & Handling

Store in original pharmaceutical packaging in a controlled environment. Maintain temperature and humidity conditions as specified. Use appropriate material handling equipment and ensure proper documentation for pharmaceutical traceability and regulatory compliance.

Controlled temperature (15-30°C)
Humidity control (≤65% RH)
Protect from contamination
Complete documentation required

Chemical Mechanisms & Reaction Pathways

Methylparaben exhibits effective antimicrobial activity through cell membrane disruption and enzymatic inhibition pathways, enabling precise preservative applications with broad-spectrum activity and pharmaceutical compatibility.

Cell Membrane Disruption

Disrupts microbial cell membrane integrity and permeability

Broad-spectrum antimicrobial activity
Enzymatic Inhibition

Inhibits key microbial enzymes and metabolic pathways

Prevents microbial growth and reproduction
pH Stability

Maintains antimicrobial activity across pharmaceutical pH ranges

Effective in various formulation conditions
Partitioning Behavior

Optimal oil-water partitioning for preservative distribution

Enhanced preservative efficacy in complex formulations

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global pharmaceutical access with complete documentation packages supporting international standards and preservative regulatory requirements.

USP-NF Specifications

United States Pharmacopeia-National Formulary preservative standards compliance

EP Standards

European Pharmacopoeia specifications for pharmaceutical preservatives

cGMP Manufacturing

Current Good Manufacturing Practice certified preservative production

IPEC Guidelines

International Pharmaceutical Excipients Council preservative quality standards

CEP Certificate

Certificate of Suitability to European Pharmacopoeia Monograph

Safety Documentation

Complete preservative safety and toxicological data package

Technical Support & Value-Added Services

DRAVYOM's preservative science team provides comprehensive formulation support, antimicrobial effectiveness guidance, and technical solutions to optimize Methylparaben performance in your pharmaceutical formulations.

Formulation Development
  • Preservative system optimization
  • Antimicrobial effectiveness testing
  • pH compatibility studies
  • Preservative synergy evaluation
Analytical Services
  • Antimicrobial testing protocols
  • Preservative content analysis
  • Stability testing programs
  • Compatibility studies
Technical Support
  • Preservative troubleshooting consultation
  • cGMP compliance guidance
  • Regulatory documentation support
  • Quality control method development
Supply Solutions
  • Consistent preservative grade specifications
  • Flexible packaging configurations
  • Just-in-time delivery programs
  • Global preservative distribution network

Environmental Impact & Sustainability

Our Methylparaben production emphasizes environmental responsibility through sustainable preservative manufacturing practices, waste minimization, and comprehensive environmental impact management for pharmaceutical operations.

Waste Minimization

Optimized synthesis with minimal preservative waste generation

Water Treatment

Advanced pharmaceutical wastewater treatment and recycling systems

Green Chemistry

Environmentally conscious preservative synthesis with emission controls

Safe Disposal

Comprehensive guidance for preservative waste management

ISO 14001

Environmental management system certified pharmaceutical production

Carbon Footprint

Reduced carbon footprint through preservative process optimization

Manufacturing Excellence & Quality Control

DRAVYOM's specialized preservative manufacturing facility employs advanced synthesis technology and continuous monitoring systems to ensure consistent Methylparaben quality and antimicrobial performance across all production batches.

Production Process

Advanced synthesis and purification in controlled preservative environment

Multi-stage crystallization for pharmaceutical grade preservative quality
Quality Testing

Comprehensive analytical testing including antimicrobial effectiveness analysis

HPLC verification and preservative efficacy testing
Quality Systems

ISO 9001:2015 quality management with preservative manufacturing accreditation

Specialized preservative quality systems
Packaging Control

Pharmaceutical-grade containers with preservative protection

Moisture control and contamination prevention

Market Applications & Performance Data

Comprehensive preservative development data demonstrating Methylparaben effectiveness across diverse pharmaceutical applications with quantified antimicrobial performance metrics and preservative system validations.

Preservative Systems
Effectiveness: 0.1-0.2% typical concentration Spectrum: Gram-positive bacteria and fungi Stability: 5+ years pharmaceutical grade
Formulation Applications
Compatibility: Wide pH range (3-8) Synergy: Enhanced with propylparaben Regulatory: Global preservative approvals
Manufacturing Benefits
Capacity: Multi-ton annual preservative production Consistency: <1.0% batch-to-batch variation Compliance: 100% preservative cGMP adherence

DRAVYOM Competitive Advantages

Preservative Expertise

Specialized preservative manufacturing with exceptional purity and antimicrobial performance

Reliable Supply

Guaranteed availability with preservative inventory management and pharmaceutical-grade scheduling

Preservative Science

Dedicated preservative development team with antimicrobial formulation expertise

Quality Assurance

Comprehensive certificates with complete analytical data and preservative documentation

Global Standards

International compliance with USP-NF, EP, and IPEC specifications for worldwide pharmaceutical acceptance

Partnership Approach

Collaborative relationships with pharmaceutical companies and custom preservative system development