HPMC - Pharmaceutical Grade Excipient
Industrial Premium
Pharmaceutical Ingredient

Hydroxypropyl Methylcellulose (HPMC)

Premium high-quality pharmaceutical excipient engineered for demanding pharmaceutical applications including tablet coating, controlled release formulations, matrix tablets, and drug delivery systems. Our pharmaceutical-grade HPMC delivers exceptional film-forming properties, consistent performance, and reliable drug release control for critical pharmaceutical processes requiring superior excipients with stringent regulatory compliance standards.

  • High Pharmaceutical Purity
  • Superior Film Formation
  • USP/EP/IP Compliant
  • Consistent Performance
  • Controlled Release
  • Drug Delivery Systems
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Technical Specifications

Chemical Name: Hydroxypropyl Methylcellulose
CAS Number: 9004-65-3
Grade: Pharmaceutical Grade USP/EP/IP
Viscosity Type: K4M, K15M, K100M available
Physical State: White to off-white powder
Methoxy Content: 19.0-24.0%
Hydroxypropoxy Content: 4.0-12.0%
Loss on Drying: ≤ 5.0%
Residue on Ignition: ≤ 1.5%
Heavy Metals (as Pb): ≤ 20 ppm
pH (1% solution): 5.0-8.0
Particle Size: 100% through 80 mesh
Microbial Limits: ≤ 1000 CFU/g
Shelf Life: 5 years
Packaging Options: 25kg fiber drums

Applications

Tablet Matrix Systems
Capsule Binding Agent
Film Coating Agent
Controlled Release Systems
Ophthalmic Solutions
Topical Formulations

Industry-Specific Grades

DRAVYOM offers specialized HPMC grades tailored for different pharmaceutical formulation requirements, ensuring optimal performance and regulatory compliance.

Tablet Grade
Viscosity: K4M, K15M, K100M Binding: Excellent Disintegration: Controlled Application: Direct compression
Coating Grade
Film Forming: Superior Transparency: High Adhesion: Excellent Application: Film coating
Ophthalmic Grade
Purity: Ultra high Endotoxin: ≤ 0.5 EU/mL Osmolality: Controlled Application: Eye drops
Sustained Release Grade
Release Profile: Customizable Swelling: Controlled Matrix: Robust Application: Extended release

Quality Standards

DRAVYOM's HPMC is manufactured under cGMP conditions, meeting international pharmaceutical standards for drug formulation applications.

cGMP Certified Manufacturing
USP/EP/IP Compliant
Pharmaceutical Grade Purity
Regulatory Approved
Complete Testing Protocol
Controlled Storage Conditions
Certificate of Analysis
Pharmaceutical Support

Advanced Chemical Properties & Performance

Pharmaceutical Grade material exhibits reliable properties suitable for pharmaceutical formulations and quality manufacturing. Its consistent composition ensures predictable performance in drug development and production environments.

Basic Properties
Pharmaceutical Grade: USP/EP compliant material
Functionality: Excipient performance properties
Compatibility: Compatible with active ingredients
Stability: Stable under pharmaceutical conditions
Physical Properties
Physical Form: Powder or granular material
Particle Size: Controlled particle distribution
Bulk Density: Optimized for processing
Flow Properties: Good flow characteristics
Pharmaceutical Performance
Formulation Suitability: Excellent for drug formulations
Processing: Suitable for various processes
Dissolution: Predictable dissolution behavior
Bioavailability: Does not affect drug bioavailability
Quality Standards
Purity: ≥99.0% pharmaceutical grade
Heavy Metals: ≤10 ppm
Microbial Limits: USP/EP compliant
Residual Solvents: Within ICH Q3C limits
Stability Properties
Shelf Life: 5 years (unopened)
Storage Stability: Stable under controlled conditions
Retest Period: As per pharmacopeial standards
Container Closure: Pharmaceutical grade packaging

Performance Characteristics

Performance metrics demonstrate pharmaceutical grade reliability in drug formulation and manufacturing applications with consistent quality, regulatory compliance, and optimal performance for pharmaceutical processes.

Formulation Performance

Efficiency: Consistent excipient functionality

Excellent for drug formulations
Regulatory Compliance

Standards: USP/EP/BP pharmacopeial compliance

Meets regulatory requirements
Manufacturing Use

Reliability: Consistent performance in production

Suitable for pharmaceutical manufacturing
Quality Assurance

Validation: Comprehensive quality testing

Validated pharmaceutical material
Batch Consistency

Variation: ±1% between batches

Superior batch-to-batch consistency
Shelf Life

Duration: 5 years under proper storage

Extended stability for pharmaceutical use

Safety Information

Generally safe for pharmaceutical use when handled according to Good Manufacturing Practices. Use appropriate protective equipment including gloves and safety goggles during handling. Follow pharmaceutical handling protocols and maintain clean room standards where applicable.

Pharmaceutical Safe
GMP Handling
Regulatory Approved

Storage & Handling

Store in original pharmaceutical packaging in a controlled environment as per ICH guidelines. Maintain appropriate temperature and humidity conditions. Use pharmaceutical storage equipment and follow Good Distribution Practices for inventory management.

Store at 15-30°C
Relative humidity ≤60%
Original pharmaceutical packaging
GMP storage conditions

Chemical Mechanisms & Reaction Pathways

HPMC exhibits unique gel-forming and film-forming properties through hydrogen bonding and polymer chain entanglement, enabling controlled drug release and pharmaceutical processing applications with predictable performance characteristics.

Gel Formation

Thermoreversible gel formation through polymer chain interaction mechanisms

Essential for sustained release formulations
Film Formation

Polymer film barrier properties for tablet coating and capsule applications

Critical for enteric and controlled release
Swelling Mechanism

Water uptake and polymer swelling for matrix tablet drug release

Enables predictable release kinetics
Viscosity Control

Molecular weight-dependent viscosity for formulation optimization

Important for processing and stability

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures pharmaceutical-grade HPMC meets international pharmacopeial standards with complete documentation packages supporting drug development and regulatory submissions.

Pharmacopeial Standards

USP, EP, and JP compliance for pharmaceutical excipient applications

GMP Compliance

Good Manufacturing Practice protocols for pharmaceutical excipients

Safety Documentation

Complete toxicological data and pharmaceutical safety profiles

International Registration

DMF filings and excipient master file documentation

Quality Documentation

Certificates of analysis and pharmaceutical quality certificates

Supply Chain

GMP-compliant transportation and pharmaceutical logistics

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical excipient support team provides comprehensive formulation guidance, technical assistance, and regulatory support to optimize HPMC applications in drug development and pharmaceutical manufacturing.

Formulation Support
  • Controlled release system design
  • Matrix tablet optimization
  • Coating formulation development
  • Capsule shell formulation
Technical Services
  • Viscosity grade selection
  • Release profile modeling
  • Stability testing guidance
  • Process optimization support
Regulatory Services
  • DMF preparation assistance
  • Regulatory submission support
  • Quality system documentation
  • Pharmacopeial compliance verification
Supply Solutions
  • Pharmaceutical-grade packaging
  • Just-in-time delivery programs
  • Custom viscosity grades
  • Inventory management services

Environmental Impact & Sustainability

Our pharmaceutical HPMC production emphasizes environmental responsibility through sustainable sourcing, energy-efficient manufacturing, and comprehensive environmental impact management for sustainable pharmaceutical development.

Sustainable Sourcing

Renewable cellulose sources with sustainable forestry practices

Green Chemistry

Environmentally friendly chemical modification processes

Clean Production

Energy-efficient manufacturing with emission controls

Waste Management

Pharmaceutical waste minimization and recycling programs

Environmental Standards

ISO 14001 environmental management system compliance

Packaging Solutions

Recyclable pharmaceutical packaging and container programs

Manufacturing Excellence & Quality Control

DRAVYOM's pharmaceutical HPMC manufacturing facility employs advanced polymer processing technology and quality systems to ensure consistent pharmaceutical-grade quality and performance across all production batches.

Advanced Processing

State-of-the-art polymer modification and purification technology

Consistent viscosity and substitution control
Quality Testing

Comprehensive testing including viscosity, substitution, and pharmaceutical properties

USP/EP method validation and compliance
GMP Systems

cGMP compliance with pharmaceutical excipient quality systems

FDA and EMA inspection-ready facilities
Pharmaceutical Packaging

Moisture-controlled packaging with pharmaceutical-grade containers

Stability-optimized packaging systems

Market Applications & Performance Data

Comprehensive pharmaceutical data demonstrating HPMC effectiveness across drug delivery applications with validated performance metrics and pharmaceutical industry adoption for controlled release systems.

Tablet Manufacturing
Release Control: 99.5% target profile achievement Performance: Consistent drug release kinetics Customer Satisfaction: 96% pharmaceutical approval
Capsule Production
Shell Quality: Superior mechanical properties Dissolution: Predictable capsule performance Market Share: 40% vegetarian capsule segment
Coating Applications
Film Quality: Excellent barrier properties Process Efficiency: 30% coating time reduction Cost Effectiveness: 20% formulation cost savings

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

cGMP-compliant HPMC manufacturing with pharmaceutical regulatory expertise and drug development support

Technical Innovation

Advanced polymer technology with custom viscosity grades and formulation optimization

Quality Assurance

Comprehensive quality control with pharmaceutical-grade documentation and batch traceability

Reliable Supply

Consistent pharmaceutical supply chain with just-in-time delivery and inventory management

Regulatory Support

DMF filing assistance with regulatory submission support and global compliance expertise

Partnership Approach

Long-term pharmaceutical partnerships with formulation development and technical collaboration