Dipotassium Glycyrrhizinate USP/EP
Pharmaceutical USP/EP
Pharmaceutical API

Dipotassium Glycyrrhizinate USP/EP

High-purity pharmaceutical grade Dipotassium Glycyrrhizinate manufactured under stringent cGMP conditions. This anti-inflammatory API is essential for hepatoprotective therapy, particularly in liver protection and chronic hepatitis treatment, providing reliable quality and regulatory compliance.

  • USP/EP Grade Pharmaceutical API
  • cGMP Manufacturing Standards
  • ≥98.0% Purity (HPLC)
  • Comprehensive COA Documentation
  • Anti-inflammatory for Liver Protection
  • Regulatory Compliance Ready
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Technical Specifications

Chemical Formula: C42H60K2O16
CAS Number: 68797-35-3
Molecular Weight: 899.13 g/mol
Purity (HPLC): ≥98.0% (pharmaceutical grade)
Physical State: White to off-white crystalline powder
Water Content (Karl Fischer): ≤5.0%
Residue on Ignition: ≤0.2%
Heavy Metals (as Pb): ≤10 ppm
Related Substances: ≤2.0% total impurities
Storage Conditions: Store in cool, dry place (15-25°C)
Packaging Options: 1kg, 5kg pharmaceutical containers

Applications

Hepatoprotective Drug Manufacturing
Liver Protection Formulations
Injectable Pharmaceutical Products
API Synthesis & Development
Anti-inflammatory Research
Pharmaceutical Research
Drug Product Manufacturing
Quality Control Testing
Regulatory Compliance
Clinical Trial Materials
Bioanalytical Method Development
Reference Standard Applications

Industry-Specific Grades

DRAVYOM offers specialized Dipotassium Glycyrrhizinate grades tailored for specific pharmaceutical requirements, ensuring optimal performance and regulatory compliance across diverse hepatoprotective drug manufacturing applications.

USP Grade (Pharmaceutical)
Purity: ≥98.0% (HPLC) Water Content: ≤5.0% Heavy Metals: ≤10 ppm Application: Pharmaceutical formulations
EP Grade (European Pharmacopoeia)
Purity: ≥98.0% (pharmaceutical) Related Substances: ≤2.0% Residue on Ignition: ≤0.2% Application: European market compliance
Research Grade
Purity: ≥97.0% (analytical) Water Content: ≤6.0% Particle Size: Controlled Application: R&D, method development
GMP Grade
Purity: ≥99.0% (pharmaceutical) Endotoxins: ≤0.5 EU/mg Microbial Limits: Compliant Application: Injectable hepatoprotective formulations

Quality Standards

DRAVYOM's pharmaceutical grade Dipotassium Glycyrrhizinate is manufactured under stringent cGMP protocols, meeting international pharmaceutical standards including USP, EP, and ICH guidelines. Our pharmaceutical-grade production ensures consistent quality and regulatory compliance.

cGMP Certified Manufacturing
USP/EP Grade Specifications
≥98.0% Pharmaceutical Purity
Advanced Analytical Testing
Ultra-Low Impurities
Batch-to-Batch Consistency
Traceable Certificate of Analysis
Temperature-Controlled Logistics

Advanced Chemical Properties & Performance

Pharmaceutical grade Dipotassium Glycyrrhizinate exhibits exceptional chemical properties essential for hepatoprotective therapy applications. Its ultra-pure composition and precise molecular structure ensure reliable performance in demanding pharmaceutical formulations and research applications.

Analytical Properties
Solubility (Water): Freely soluble
LogP (octanol/water): -2.3
pKa: 4.2
Molecular Weight: 899.13 g/mol
Physical Properties
Appearance: White to off-white powder
Melting Point: 220-225°C (with decomposition)
Bulk Density: 0.5-0.7 g/mL
Hygroscopicity: Hygroscopic
Pharmaceutical Performance
Bioavailability: High (oral/IV)
Protein Binding: 85%
Half-life: 4-6 hours
Mechanism: Hepatoprotective, anti-inflammatory
Purity Specifications
Assay (HPLC): ≥98.0%
Related Substances: ≤1.0% total
Water Content: ≤8.0% (Karl Fischer)
Residue on Ignition: ≤0.2%
Stability Properties
Shelf Life: 2 years (unopened)
Light Sensitivity: Protect from light
Temperature Stability: Store below 25°C
pH Stability: Stable in neutral to alkaline pH

Performance Characteristics

Detailed performance metrics demonstrate pharmaceutical grade Dipotassium Glycyrrhizinate superiority in hepatoprotective applications with exceptional liver protection, anti-inflammatory activity, and reproducibility across diverse therapeutic protocols.

Hepatoprotective Activity

Strong liver protective properties

Protects against hepatotoxic agents
Anti-inflammatory

Reduces hepatic inflammation

Inhibits inflammatory mediators
Stability Profile

Chemical stability: Good under storage conditions

Maintains potency for 2 years
Thermal Stability

Decomposition: 220-225°C

Stable during pharmaceutical processing
Batch Reproducibility

Variation: ±0.5% between batches

Consistent therapeutic efficacy
High Solubility

Excellent water solubility

Suitable for injectable formulations

Safety Information

Pharmaceutical ingredient requiring professional handling. Well-established safety profile for hepatoprotective therapy. Handle with pharmaceutical-grade safety precautions and ensure proper GMP environmental controls. Clinical monitoring for electrolyte balance during therapeutic use.

Pharmaceutical Grade
Professional Use
Monitor electrolytes

Storage & Handling

Store in original containers in a cool, dry, well-ventilated area away from moisture and light. Keep containers tightly closed and maintain pharmaceutical-grade environmental controls. Use appropriate GMP handling techniques for API processing.

Cool storage (15-25°C)
Protect from moisture (hygroscopic)
Protect from light
GMP handling required

Chemical Mechanisms & Reaction Pathways

Dipotassium Glycyrrhizinate exhibits anti-inflammatory and hepatoprotective properties through multiple biochemical pathways, including prostaglandin synthesis inhibition and cellular membrane stabilization mechanisms.

Anti-inflammatory Action

Inhibits prostaglandin and leukotriene synthesis pathways

Reduces inflammatory cascade activation
Membrane Stabilization

Stabilizes cellular membranes and reduces permeability

Protects hepatocytes from damage
Antioxidant Activity

Scavenges free radicals and reactive oxygen species

Prevents oxidative cellular damage
Enzyme Interactions

Modulates hepatic enzyme activity and metabolism

Enhances liver detoxification processes

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures pharmaceutical manufacturing access with complete documentation packages supporting international standards and pharmaceutical method validations.

USP Standards

United States Pharmacopeia pharmaceutical specifications compliance

EP Monograph

European Pharmacopoeia specifications and testing protocols

GMP Certification

Good Manufacturing Practices compliance for pharmaceutical production

ICH Guidelines

International Council for Harmonisation regulatory compliance

DMF Support

Drug Master File documentation and regulatory filing support

API Documentation

Complete pharmaceutical API documentation packages

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical development team provides comprehensive formulation support, stability testing, and regulatory services to optimize Dipotassium Glycyrrhizinate performance in your pharmaceutical applications.

Formulation Development
  • Pharmaceutical formulation optimization
  • Stability testing protocols
  • Bioavailability enhancement
  • Custom pharmaceutical development
Analytical Services
  • API purity analysis and validation
  • Impurity profiling and identification
  • Pharmaceutical testing services
  • Method validation support
Regulatory Support
  • Regulatory filing assistance
  • DMF preparation and maintenance
  • International compliance guidance
  • Pharmacovigilance support
Supply Solutions
  • Reliable pharmaceutical supply chain
  • Custom packaging solutions
  • Global distribution network
  • Emergency supply arrangements

Environmental Impact & Sustainability

Our Dipotassium Glycyrrhizinate production emphasizes environmental responsibility through sustainable pharmaceutical manufacturing practices, waste minimization, and comprehensive environmental impact management.

Green Chemistry

Environmentally friendly synthesis and processing methods

Water Conservation

Advanced water treatment and recycling systems

Clean Production

Energy-efficient pharmaceutical manufacturing processes

Waste Reduction

Comprehensive pharmaceutical waste management protocols

ISO 14001

Environmental management system certified production

Natural Sourcing

Sustainable extraction from natural licorice sources

Manufacturing Excellence & Quality Control

DRAVYOM's pharmaceutical manufacturing facility employs advanced purification technology and continuous monitoring systems to ensure consistent Dipotassium Glycyrrhizinate quality and performance across all production batches.

GMP Production

State-of-the-art pharmaceutical manufacturing in controlled clean-room environment

Multi-stage purification for pharmaceutical grade quality
Quality Testing

Comprehensive analytical testing protocol including assay, impurities, and stability

HPLC verification and pharmaceutical analysis
Quality Systems

ISO 9001:2015 quality management with pharmaceutical compliance

Continuous improvement and pharmaceutical validation
Pharmaceutical Packaging

Pharmaceutical-grade containers with moisture protection

Stability protection and contamination prevention

Market Applications & Performance Data

Comprehensive pharmaceutical data demonstrating Dipotassium Glycyrrhizinate effectiveness across diverse therapeutic applications with quantified performance metrics and clinical validations.

Pharmaceutical Formulations
Bioavailability: 85-95% oral absorption Stability: 2-year shelf life validated Compatibility: Excellent with excipients
Therapeutic Applications
Hepatoprotection: Clinically proven efficacy Anti-inflammatory: Reduced inflammation markers Safety Profile: Well-tolerated therapeutic use
Manufacturing Performance
Yield: 98% pharmaceutical grade recovery Purity: >99% pharmaceutical specification Consistency: 99.5% batch-to-batch reproducibility

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

Superior pharmaceutical grade quality with consistent therapeutic performance and regulatory compliance

Reliable Supply

Guaranteed availability with strategic inventory management and pharmaceutical production scheduling

Formulation Expertise

Dedicated pharmaceutical development team provides formulation and regulatory support

Regulatory Compliance

Complete pharmaceutical documentation with DMF support and international compliance

Global Standards

International pharmaceutical compliance with USP, EP, and ICH guidelines

Partnership Approach

Collaborative relationships with pharmaceutical manufacturers and custom development services