Cellulose Acetate Phthalate (CAP)
Pharmaceutical Premium
Pharmaceutical Excipient

Cellulose Acetate Phthalate (CAP)

High-purity pharmaceutical Cellulose Acetate Phthalate manufactured to meet stringent USP and EP specifications for enteric coating applications. Our CAP provides excellent gastric resistance and film formation properties for targeted drug delivery systems.

  • USP/EP Pharmaceutical Grade
  • Superior Enteric Properties
  • Excellent Film Formation
  • Enhanced Gastric Resistance
  • Consistent Quality
  • Ultra-Low Impurities
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Technical Specifications

Chemical Formula: [C6H7O2(OH)3-m-n(OCOCH3)m(OOC-C6H4-COOH)n]x
CAS Number: 9004-38-0
Molecular Weight: Variable (polymer)
Purity (Assay): ≥98.0% (pharmaceutical grade)
Physical State: White to off-white granular powder
Water Content (Loss on Drying): ≤5.0%
Acetyl Content: 22.0-26.0%
Heavy Metals (as Pb): ≤10 ppm
Phthalyl Content: 30.0-36.0%
Storage Conditions: Store in cool, dry place (15-30°C)
Packaging Options: 25kg, 50kg pharmaceutical drums

Applications

Enteric Coating Applications
Gastric Resistance Films
Modified Release Formulations
Pharmaceutical Excipient
Film Coating Research
Pharmaceutical Research
Drug Product Manufacturing
Quality Control Testing
Targeted Drug Delivery
Formulation Development
Coating Technology Research
Reference Standard Applications

Industry-Specific Grades

DRAVYOM offers specialized Cellulose Acetate Phthalate grades tailored for specific pharmaceutical requirements, ensuring optimal performance and regulatory compliance across diverse enteric coating applications.

USP Grade (Pharmaceutical)
Purity: ≥98.0% (assay) Water Content: ≤5.0% Heavy Metals: ≤10 ppm Application: Pharmaceutical formulations
EP Grade (European Pharmacopoeia)
Purity: ≥98.0% (pharmaceutical) Acetyl Content: 22.0-26.0% Phthalyl Content: 30.0-36.0% Application: European market compliance
High Performance Grade
Purity: ≥99.0% (pharmaceutical) Film Quality: Superior Dissolution: Controlled Application: Premium enteric coatings
GMP Grade
Purity: ≥98.5% (pharmaceutical) Microbial Limits: Compliant Endotoxins: ≤2.5 EU/g Application: Modified release formulations

Quality Standards

DRAVYOM's pharmaceutical grade Cellulose Acetate Phthalate is manufactured under stringent cGMP protocols, meeting international pharmaceutical standards including USP, EP, and ICH guidelines. Our pharmaceutical-grade production ensures consistent quality and regulatory compliance.

cGMP Certified Manufacturing
USP/EP Grade Specifications
≥98.0% Pharmaceutical Purity
Advanced Analytical Testing
Comprehensive Quality Control
Batch-to-Batch Consistency
Complete Documentation Package
Controlled Storage & Logistics

Advanced Chemical Properties & Performance

Pharmaceutical grade Cellulose Acetate Phthalate exhibits exceptional chemical properties essential for enteric coating applications. Its ultra-pure composition and precise molecular structure ensure reliable performance in demanding pharmaceutical formulations and research applications.

Analytical Properties
Solubility (Water): Practically insoluble
pH Solubility: Soluble pH >6.0
Viscosity: 15-30 cP (2% acetone)
Molecular Weight: 30,000-60,000 Da
Physical Properties
Glass Transition: 165-185°C
Bulk Density: 0.2-0.4 g/mL
Crystalline Form: White to off-white powder
Hygroscopicity: Non-hygroscopic
Pharmaceutical Performance
Enteric Protection: Gastric resistant
Film Formation: Excellent
Coating Efficiency: High coating yield
Adhesion: Strong tablet adhesion
Purity Specifications
Phthalyl Content: 30.0-36.0%
Acetyl Content: 19.0-23.5%
Heavy Metals: ≤20 ppm
Loss on Drying: ≤5.0%
Stability Properties
Shelf Life: 3 years (unopened)
Light Sensitivity: Not light sensitive
Temperature Stability: Stable 15-30°C
Container Compatibility: HDPE, paper bags

Performance Characteristics

Detailed performance metrics demonstrate pharmaceutical grade Cellulose Acetate Phthalate superiority in enteric coating applications with exceptional gastric resistance, film formation, and reproducibility across diverse pharmaceutical formulations and oral dosage protocols.

Gastric Resistance

Excellent acid resistance properties

Superior gastric protection
Film Formation

Uniform coating film formation

Consistent enteric protection
Dissolution Profile

pH-dependent dissolution achieved

Controlled drug release
Temperature Stability

Stable under ambient conditions

Consistent performance 15-30°C
Batch Reproducibility

Variation: ±0.2% between batches

Exceptional lot-to-lot consistency
Shelf Stability

3 years under proper storage conditions

Extended pharmaceutical grade integrity

Safety Information

Handle with standard pharmaceutical safety precautions. Use appropriate personal protective equipment including safety goggles, gloves, and protective clothing. Avoid inhalation of powder and ensure adequate ventilation in work areas. Follow established pharmaceutical handling protocols.

Generally Safe
Avoid Inhalation
Wear Gloves

Storage & Handling

Store in original containers in a cool, dry place protected from moisture. Keep containers tightly closed and maintain pharmaceutical storage conditions. Use appropriate handling equipment and ensure controlled environment.

Store at 15-30°C
Protect from moisture
Original packaging
Keep containers tightly closed

Chemical Mechanisms & Reaction Pathways

Cellulose Acetate Phthalate exhibits pH-dependent dissolution properties through polymer chain interactions, enabling predictable enteric coating performance with well-characterized dissolution profiles.

Mechanism of Action

pH-dependent polymer dissolution and swelling

Gastric resistance and intestinal release
Polymer Structure

Acetyl and phthalyl substitution on cellulose backbone

Controlled dissolution mechanism
Dissolution Profile

Insoluble below pH 6.0, soluble above pH 6.2

Enteric coating threshold
Film Formation

Continuous polymer film with controlled permeability

Uniform coating performance

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global pharmaceutical market access with complete documentation packages supporting international drug registration and regulatory submissions.

USP Monograph

United States Pharmacopeia specifications compliance

EP Standards

European Pharmacopoeia monograph requirements

cGMP Manufacturing

Current Good Manufacturing Practices compliance

ICH Guidelines

International Council for Harmonisation standards

DMF Support

Drug Master File documentation assistance

Audit Readiness

Regulatory inspection preparation and support

Technical Support & Value-Added Services

DRAVYOM's pharmaceutical development team provides comprehensive formulation support, regulatory guidance, and technical services to optimize Cellulose Acetate Phthalate performance in your specific pharmaceutical applications.

Formulation Development
  • Coating solution optimization
  • Stability testing protocols
  • Dissolution method development
  • Process parameter optimization
Analytical Services
  • Method validation support
  • Polymer characterization
  • Dissolution testing
  • Pharmaceutical testing
Technical Support
  • Regulatory compliance guidance
  • Quality assurance protocols
  • Manufacturing process support
  • Documentation preparation
Supply Solutions
  • Pharmaceutical grade scheduling
  • Global regulatory shipping
  • Custom packaging options
  • Emergency supply protocols

Environmental Impact & Sustainability

Our Cellulose Acetate Phthalate production emphasizes environmental responsibility through sustainable pharmaceutical manufacturing practices, waste minimization, and comprehensive environmental impact management.

Waste Minimization

Optimized synthesis with minimal pharmaceutical waste

Water Treatment

Advanced wastewater treatment and recycling systems

Clean Production

Energy-efficient synthesis with emission controls

Safe Disposal

Pharmaceutical waste management guidance

ISO 14001

Environmental management system certification

Green Chemistry

Sustainable pharmaceutical synthesis methods

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art pharmaceutical manufacturing facility employs advanced synthesis technology and continuous monitoring systems to ensure consistent Cellulose Acetate Phthalate quality and performance across all production batches.

cGMP Production

Current Good Manufacturing Practices in controlled pharmaceutical environment

FDA and WHO-GMP certified facility
Quality Testing

Comprehensive pharmaceutical testing including identity, purity, and dissolution

USP/EP monograph compliance verification
Quality Systems

ISO 9001:2015 with pharmaceutical quality management

Continuous improvement and validation
Packaging Control

Pharmaceutical-grade packaging with moisture protection

Stability and contamination prevention

Market Applications & Performance Data

Comprehensive pharmaceutical data demonstrating Cellulose Acetate Phthalate effectiveness across diverse coating applications with quantified performance metrics and formulation validation.

Enteric Coating Applications
Dissolution: <5% release at pH 1.2 Release: >85% at pH 6.8 in 60 min Stability: 3+ years coated tablets
Pharmaceutical Performance
Uniformity: <5% coating weight variation Adhesion: Excellent film integrity Processability: 15-20% coating solutions
Manufacturing Data
Purity: >99.0% pharmaceutical grade Consistency: ±0.2% batch variation Yield: >98% polymer recovery

DRAVYOM Competitive Advantages

Pharmaceutical Excellence

Consistently exceeds USP/EP specifications with exceptional pharmaceutical quality and performance

Reliable Supply

Guaranteed pharmaceutical-grade availability with cGMP production scheduling

Development Expertise

Dedicated pharmaceutical development team providing formulation and regulatory support

Quality Assurance

Comprehensive COA with pharmaceutical testing and regulatory compliance documentation

Global Standards

International compliance with USP, EP, and ICH guidelines for worldwide market access

Partnership Approach

Collaborative relationships with pharmaceutical companies and custom excipient development