Industrial Grade Guanidine Hydrochloride
Industrial Biochemical Grade
Industrial Chemical

Industrial Grade Guanidine Hydrochloride

High-purity Industrial Grade Guanidine Hydrochloride specifically formulated for protein denaturation and biochemical applications. Our guanidine hydrochloride delivers excellent denaturing properties and consistent performance for pharmaceutical, research, and industrial processes requiring reliable biochemical reagents.

  • ≥99% Purity Level
  • Excellent Denaturing Properties
  • High Solubility
  • Industrial Grade Quality
  • Pharmaceutical Compatible
  • Consistent Performance
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Technical Specifications

Product Type: Guanidine hydrochloride, biochemical grade
Chemical Formula: CH₅N₃·HCl
Molecular Weight: 95.53 g/mol
Purity: ≥ 99.0% (HPLC)
Appearance: White crystalline powder
Solubility in Water: 230 g/100mL at 25°C
pH (1M solution): 4.5-6.0
Melting Point: 182-184°C
Loss on Drying: ≤ 0.5% at 105°C
Residue on Ignition: ≤ 0.1%
Heavy Metals: ≤ 10 ppm as Pb
Chloride Content: 37.0-37.5% as Cl⁻
Sulfate: ≤ 0.02% as SO₄²⁻
Iron: ≤ 5 ppm as Fe
DNase Activity: None detected
RNase Activity: None detected
Package Sizes: 100g, 500g, 1kg, 25kg
Storage: Room temperature, dry place

Applications

Protein Denaturation
RNA/DNA Purification
Protein Extraction
Protein Sequencing
Cell Lysis Buffer
Pharmaceutical Synthesis
Biochemical Research
Diagnostic Assays
Plant Tissue Studies
Microbiology Applications
Analytical Chemistry
Industrial Biotechnology

Industry-Specific Grades

DRAVYOM offers specialized guanidine hydrochloride formulations tailored for specific biochemical applications, ensuring optimal purity, nuclease-free quality, and performance for diverse research and industrial requirements.

Molecular Biology Grade
Purity: ≥ 99.5% DNase/RNase: Free Endotoxin: ≤ 0.1 EU/mg Application: DNA/RNA work
Biochemical Grade
Purity: ≥ 99.0% Heavy Metals: ≤ 10 ppm Cost: Economical Application: General biochemistry
Pharmaceutical Grade
Purity: ≥ 99.8% Standards: USP/EP grade Residue: ≤ 0.05% Application: Drug synthesis
Industrial Grade
Purity: ≥ 98.5% Volume: Bulk availability Cost: Most economical Application: Industrial processes

Quality Standards

DRAVYOM's guanidine hydrochloride is manufactured under stringent quality control protocols, meeting international biochemical standards including USP, EP, and industry specifications for molecular biology and pharmaceutical applications.

ISO 9001:2015 Certified Manufacturing
USP/EP Standards Compliance
≥ 99.0% Purity by HPLC
HPLC Purity Analysis
DNase/RNase Activity Testing
≤ 10 ppm Heavy Metals
Biochemical Quality Certificate
Cold Chain Storage & Shipping

Advanced Chemical Properties & Performance

Guanidine Hydrochloride exhibits exceptional chemical properties essential for protein research and pharmaceutical applications. Its ultra-pure composition and strong denaturing capability ensure reliable performance in demanding biochemical procedures.

Chemical Properties
Molecular Formula: CH₅N₃·HCl
Molecular Weight: 95.53 g/mol
Purity: ≥ 99.0%
pH (1M solution): 4.5-5.5
Physical Properties
Melting Point: 180-185°C
Density: 1.35 g/cm³
Solubility in Water: Highly soluble (>80 g/100 ml)
Appearance: White crystalline solid
Biochemical Properties
Denaturing Concentration: 6-8 M effective
Protein Unfolding: Complete at 6 M
Nucleic Acid Interaction: RNA/DNA stabilization
Enzyme Compatibility: Inhibits most enzymes
Purity Analysis
Residue on Ignition: ≤ 0.05%
Heavy Metals: ≤ 10 ppm
Sulfate (SO₄): ≤ 0.01%
Loss on Drying: ≤ 0.5%
Stability Properties
Shelf Life: 5 years in sealed containers
Solution Stability: Stable at 4°C for months
Light Sensitivity: Minimal degradation
Hygroscopic Nature: Moderately hygroscopic

Performance Characteristics

Detailed performance metrics demonstrate Guanidine Hydrochloride superiority in protein research applications with exceptional denaturing capability, high purity, and consistent quality for demanding biochemical procedures.

Denaturing Power

Concentration: 6-8 M effective range

Complete protein unfolding
Purity Level

Purity: ≥ 99.0% achieved

Research grade quality
Solubility

Water: >80 g/100 ml at 20°C

Excellent dissolution properties
Thermal Stability

Melting point: 180-185°C

High thermal stability
Storage Life

Shelf life: 5 years sealed storage

Extended stability
Batch Consistency

Variation: ±0.1% between batches

Exceptional lot-to-lot uniformity

Safety Information

May cause eye, skin, and respiratory irritation. Avoid dust formation and inhalation. Use appropriate protective equipment including safety goggles, gloves, and lab coats. Ensure adequate ventilation when handling. Wash hands thoroughly after use. Store away from food and feed materials.

Irritant
Eye Irritation
Respiratory Irritant

Storage & Handling

Store in original sealed containers in a cool, dry place away from moisture and incompatible materials. Use desiccants to prevent moisture absorption. Handle with appropriate laboratory protective equipment. Prepare solutions using distilled water and store at 4°C for extended use.

Cool, dry storage required
Moisture protection essential
Laboratory grade handling
Refrigerate solutions at 4°C

Chemical Mechanisms & Reaction Pathways

Guanidine Hydrochloride exhibits complex protein denaturation mechanisms through chaotropic effects and hydrogen bonding disruption, enabling protein unfolding for biochemical and pharmaceutical applications.

Protein Denaturation

Disruption of protein secondary and tertiary structures

Effective chaotropic agent for biochemistry
Hydrogen Bonding

Interference with intramolecular protein hydrogen bonds

Controlled protein unfolding
Solubility Enhancement

Improved solubility of hydrophobic compounds

Enhanced extraction efficiency
pH Stability

Stable performance across pH ranges in biological systems

Consistent biochemical applications

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global biochemical industry access with complete documentation supporting international pharmaceutical and research standards.

USP Standards

United States Pharmacopeia pharmaceutical grade

ISO 9001

International quality management system compliance

FDA Compliance

Food and Drug Administration regulatory compliance

REACH Registration

European Union chemical regulation compliance

GMP Certification

Good Manufacturing Practice pharmaceutical compliance

SDS Documentation

Multi-language Safety Data Sheets (GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's biochemical specialists provide comprehensive guanidine hydrochloride support, protein chemistry guidance, and technical services for pharmaceutical and research applications.

Protocol Development
  • Protein denaturation protocols
  • Concentration optimization
  • Buffer system development
  • Custom formulation services
Analytical Services
  • Purity analysis
  • Residual solvent testing
  • Endotoxin testing
  • Microbiological validation
Technical Support
  • Biochemical troubleshooting
  • Protein chemistry optimization
  • Research protocols
  • Pharmaceutical best practices
Supply Solutions
  • Research scheduling
  • Emergency supply
  • Custom grades
  • Pharmaceutical distribution

Environmental Impact & Sustainability

Our Guanidine Hydrochloride production emphasizes environmental responsibility through sustainable pharmaceutical chemistry, waste minimization, and comprehensive environmental management.

Chemical Recovery

Advanced crystallization and purification recycling

Water Treatment

Pharmaceutical-grade water treatment and recycling

Process Efficiency

Optimized synthesis reduces waste generation

Safe Disposal

Controlled disposal protocols for biochemical waste

Green Chemistry

Sustainable synthesis with minimized environmental impact

Container Recovery

Pharmaceutical container return and recycling

Manufacturing Excellence & Quality Control

DRAVYOM's pharmaceutical facility employs advanced crystallization technology to ensure consistent Guanidine Hydrochloride quality for critical biochemical applications.

Chemical Processing

Precision crystallization in controlled clean room environments

Pharmaceutical-grade purity and quality
Quality Testing

Comprehensive biochemical performance validation

Protein denaturation and purity testing
Quality Systems

ISO 9001:2015 and GMP certified pharmaceutical production

Continuous improvement and validation
Storage Systems

Humidity-controlled storage with stability preservation

Maintained biochemical activity

Market Applications & Performance Data

Comprehensive biochemical application data demonstrating Guanidine Hydrochloride effectiveness across diverse research applications with quantified performance metrics.

Protein Research
Denaturation: 6M concentration standard Efficiency: >95% protein unfolding Reversibility: Controlled refolding protocols
Pharmaceutical Development
Applications: 50+ drug formulations Purity: >99% pharmaceutical grade Stability: Extended shelf life validation
Biotechnology
Cell Lysis: Effective protein extraction Purification: Enhanced yield protocols Research: 200+ published applications

DRAVYOM Competitive Advantages

Pharmaceutical Grade

Exceptional purity and quality standards for critical biochemical and pharmaceutical applications

Reliable Supply

Guaranteed availability with pharmaceutical expertise and regulatory compliance support

Biochemical Expertise

Dedicated protein chemistry team provides application support and protocol development

Quality Assurance

Comprehensive testing with biochemical performance validation and regulatory documentation

Global Standards

International compliance with pharmaceutical and biochemical standards for worldwide acceptance

Partnership Approach

Collaborative relationships with pharmaceutical companies and custom grade development