Nisin (Food Grade)
Food Grade Natural
Food Ingredients

Nisin (Food Grade)

Premium food grade nisin, a natural antimicrobial peptide (bacteriocin) for food preservation. This naturally occurring preservative is highly effective against gram-positive bacteria in dairy products, canned foods, and processed meats while being completely natural and safe.

  • Natural Antimicrobial Peptide
  • Effective Against Gram-Positive Bacteria
  • Naturally Occurring Bacteriocin
  • Ideal for Dairy Products
  • Safe & Natural Preservation
  • Professional Food Grade
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Technical Specifications

Chemical Name: Nisin
E Number: E234
CAS Number: 1414-45-5
Chemical Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇
Molecular Weight: 3354 Da
Type: Polycyclic peptide antibiotic
Source: Lactococcus lactis
Physical State: Off-white to light tan powder
Solubility: Water-soluble (acidic pH)
pH Stability: 2.0-5.0
Activity: ≥1,000 IU/mg
Packaging: 1kg, 5kg aluminum cans

Applications

Cheese Products
Processed Meats
Beverages
Baked Goods
Canned Foods
Dairy Products
Ready-to-Eat Meals
Infant Formula
Antimicrobial Agent
Food Preservation
Natural Preservative
Shelf Life Extension

Industry-Specific Grades

DRAVYOM offers specialized nisin grades tailored for specific applications, ensuring optimal antimicrobial performance and regulatory compliance across diverse food preservation formulations.

Food Grade
Activity: ≥1,000 IU/mg Heavy Metals: ≤40 ppm Microbial Limits: Low Application: Food preservation
Dairy Grade
Activity: High against L. monocytogenes Heat stability: Enhanced pH tolerance: Acidic conditions Application: Cheese, yogurt
Meat Processing Grade
Spore inhibition: Effective Heat processing: Compatible Pathogen control: Broad spectrum Application: Cured meats, sausages
Canned Food Grade
Heat resistance: High Botulism prevention: Excellent Thermal processing: Stable Application: Canned vegetables, soups

Quality Standards

DRAVYOM's Nisin is manufactured under stringent quality control protocols, meeting international food safety standards and regulatory requirements for consistent antimicrobial preservation performance.

ISO 22000:2018 Food Safety Management
FCC & EU Preservative Standards
Broad Spectrum Antimicrobial
Advanced Bioactivity Testing
Fermentation-Based Production
Natural Bacteriocin
Certificate of Analysis
Sustainable Production

Advanced Chemical Properties & Performance

Food Grade Nisin exhibits exceptional chemical properties essential for food applications. Its ultra-pure composition and precise antimicrobial characteristics ensure reliable performance in demanding food preservation and bacterial inhibition applications.

Analytical Properties
Activity (IU/mg): ≥ 900
Protein Content: ≥ 2.5%
Loss on Drying: ≤ 6.0%
pH (1% solution): 3.5-4.5
Physical Properties
Appearance: Light brown powder
Solubility: Freely soluble in water
Odor: Characteristic, not offensive
Particle Size: 95% through 80 mesh
Antimicrobial Performance
MIC (Gram-positive): 0.05-10 ppm
Spectrum: Gram-positive bacteria
Usage Level: 2.5-25 ppm typical
Heat Stability: Stable up to 121°C
Purity Specifications
Heavy Metals: ≤ 10 ppm
Lead: ≤ 1 ppm
Arsenic: ≤ 1 ppm
Total Plate Count: ≤ 10 CFU/g
Stability Properties
Shelf Life: 24 months (unopened)
pH Stability: Most stable pH 3-4
Light Sensitivity: Stable to light
Freeze-Thaw: Multiple cycles stable

Performance Characteristics

Detailed performance metrics demonstrate Nisin superiority in food applications with exceptional antimicrobial efficacy, heat stability, and preservation enhancement across diverse food safety applications.

Antimicrobial Efficacy

Protection: 99.9%+ gram-positive bacteria inhibition

Superior pathogen control
Heat Stability

Stable through pasteurization and sterilization

Processing-resistant preservation
Shelf Life Extension

Extension: 100-300% longer product life

Significant preservation improvement
Natural Origin

Fermentation-derived bacteriocin

Natural preservation solution
Taste Impact

Minimal impact on food flavor at use levels

Clean preservation technology
Low Usage Levels

Effective at 2.5-25 ppm concentrations

Cost-effective preservation

Safety Information

Generally Recognized as Safe (GRAS) food preservative with no known adverse effects at normal usage levels. Handle with standard food safety practices including clean handling equipment, proper storage conditions, and adherence to Good Manufacturing Practices (GMP).

GRAS Status
Food Safe
Natural Origin

Storage & Handling

Store in original sealed containers in a cool, dry area. Keep containers tightly closed to prevent moisture absorption and maintain product activity. Use clean, dry handling equipment to prevent contamination. Refrigerated storage preferred for extended shelf-life.

Cool storage (2-8°C preferred)
Dry conditions (RH < 65%)
Original sealed packaging
Refrigerated storage optimal

Chemical Mechanisms & Reaction Pathways

Nisin functions as a natural antimicrobial agent through bacteriocin structure, creating bacterial cell membrane disruption and selective antimicrobial activity for food preservation through lipid II binding mechanisms.

Membrane Pore Formation

Binds to lipid II in bacterial cell membranes creating pores

Leads to cell death through membrane disruption
Selective Activity

Targets Gram-positive bacteria while preserving beneficial microorganisms

Maintains food quality while extending shelf life
Heat Stability

Maintains activity through pasteurization processes

Effective in heat-treated food products
pH Sensitivity

Optimized activity in acidic food environments

Enhanced effectiveness in low pH applications

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global food industry access with complete documentation packages supporting international food safety standards and natural preservative approval requirements.

FDA GRAS Status

Generally Recognized as Safe for food applications

E234 Approval

European food additive approval for natural preservative use

HACCP Certified

Hazard Analysis Critical Control Points system

Codex Alimentarius

International food preservative standards compliance

Natural Origin

Derived from Lactococcus lactis fermentation

Clean Label

Natural preservative for clean label formulations

Technical Support & Value-Added Services

DRAVYOM's food technology team provides comprehensive preservation support, antimicrobial application guidance, and technical services to optimize nisin performance in your specific food applications.

Preservation Science
  • Antimicrobial efficacy studies
  • Shelf life extension validation
  • Application method optimization
  • Custom preservation solutions
Analytical Services
  • Nisin activity testing
  • Microbiological validation
  • Stability studies
  • Efficacy verification
Technical Support
  • Application troubleshooting
  • Storage and handling guidance
  • Quality control protocols
  • Regulatory compliance assistance
Supply Solutions
  • Custom activity units
  • Flexible packaging options
  • Cold chain management
  • Technical documentation packages

Environmental Impact & Sustainability

Our nisin production emphasizes environmental responsibility through sustainable fermentation processes, natural origin sourcing, and comprehensive waste management for food industry applications.

Biofermentation

Natural production using Lactococcus lactis fermentation

Water Management

Closed-loop processing with water treatment and recycling

Green Processing

Environmentally friendly purification processes

Biodegradability

Natural protein degradation in environmental conditions

Carbon Footprint

Reduced greenhouse gas emissions through bioprocessing

Packaging Sustainability

Recyclable and reduced packaging materials

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art food ingredient manufacturing facility employs advanced fermentation and purification technology to ensure consistent nisin quality and antimicrobial effectiveness across all production batches.

Production Process

Advanced fermentation in controlled sterile environment

Precise antimicrobial activity optimization
Quality Testing

Comprehensive testing including activity, purity, and microbiological safety

Real-time monitoring and batch verification
Food Safety Systems

HACCP and ISO 22000 food safety management systems

Continuous improvement and preventive controls
Packaging Control

Cold storage packaging with activity preservation

Stability maintenance and contamination prevention

Market Applications & Performance Data

Comprehensive food industry data demonstrating nisin effectiveness across diverse applications with quantified performance metrics and antimicrobial validations.

Dairy Products
Spoilage Prevention: 99% effectiveness Shelf Life: 200% extension Quality Maintenance: Preserved texture
Processed Meats
Bacterial Control: 95% reduction Safety Enhancement: Listeria prevention Quality Preservation: Extended freshness
Beverages
Stability Improvement: Enhanced shelf life Quality Control: Maintained flavor Safety Assurance: Pathogen prevention

DRAVYOM Competitive Advantages

Superior Activity

Consistently high-activity nisin with exceptional antimicrobial effectiveness and selectivity

Reliable Supply

Guaranteed availability with controlled fermentation and flexible production scheduling

Preservation Expertise

Dedicated food scientists provide application development and preservation optimization support

Quality Assurance

Comprehensive certificates with activity data and food safety compliance documentation

Global Standards

International compliance with FDA, EU, and Codex standards for worldwide acceptance

Partnership Approach

Collaborative relationships with food manufacturers and custom preservation solutions