Alpha-Arbutin
Cosmetic Brightening
Cosmetic Ingredients

Alpha-Arbutin

Natural skin brightening agent with powerful tyrosinase inhibiting properties. Safe and effective alternative to hydroquinone for achieving even skin tone and reducing hyperpigmentation.

  • Natural Brightening Agent
  • Tyrosinase Inhibitor
  • Safe Alternative
  • Even Skin Tone
  • Reduces Hyperpigmentation
  • Gentle on Skin
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Technical Specifications

Chemical Name: Alpha-Arbutin
CAS Number: 84380-01-8
INCI Name: Alpha-Arbutin
Molecular Formula: C12H16O7
Molecular Weight: 272.25 g/mol
Physical Form: White crystalline powder
Melting Point: 199-201°C
Solubility: Water soluble
pH (5% solution): 5.0 - 7.0
Purity (HPLC): ≥ 99.0%
Loss on Drying: ≤ 0.5%
Heavy Metals: ≤ 10 ppm

Applications

Skin Brightening Agent
Hyperpigmentation Treatment
Anti-aging Formulations
Dark Spot Correctors
Whitening Serums
Face Creams
Protective Formulations
Sensitive Skin Products
Natural Cosmetics
Night Care Products
Gentle Lightening
Premium Skincare

Industry-Specific Grades

DRAVYOM offers specialized Alpha-Arbutin grades tailored for specific cosmetic applications, ensuring optimal performance and regulatory compliance across diverse skin brightening and anti-aging formulations.

Standard Cosmetic Grade
Purity: ≥ 99% Particle Size: 80-120 mesh Moisture: ≤ 0.5% Application: General brightening products
Premium Grade
Purity: ≥ 99.5% Heavy Metals: ≤ 5 ppm Microbials: Ultra-low count Application: High-end skincare products
Sensitive Skin Grade
Purity: ≥ 99.8% Allergens: Tested free Irritation: Dermatologically tested Application: Sensitive skin formulations
Natural Grade
Source: Plant-derived Processing: Natural extraction Certification: Natural cosmetic approved Application: Natural and organic cosmetics

Quality Standards

DRAVYOM's Alpha-Arbutin is manufactured under stringent quality control protocols, meeting international cosmetic standards including USP, EP, and global regulatory specifications. Our high-purity production ensures consistent performance and safety compliance.

ISO 22716 GMP Certified
≥ 99% Purity Guaranteed
HPLC Verified Quality
Advanced Analytical Testing
Dermatologically Tested
Skin Safety Verified
Complete COA Documentation
Protected Storage & Transport

Advanced Chemical Properties & Performance

Alpha Arbutin exhibits exceptional chemical properties essential for cosmetic applications. Its glycosidic structure and tyrosinase inhibition capabilities ensure reliable performance in diverse skin brightening formulations and depigmentation applications.

Molecular Properties
Molecular Weight: 272.25 g/mol
Solubility (water, 25°C): 25 g/100mL
Melting Point: 199-201°C
Crystalline Form: White crystalline powder
Physical Properties
pH (1% solution): 5.0-7.0
Stability pH Range: 3.0-8.0
Hygroscopicity: Low moisture absorption
Optical Activity: [α]D20: +158° to +162°
Biological Activity
Tyrosinase Inhibition: IC50: 0.7 μM
Melanin Reduction: Up to 40% at 1%
Skin Brightening: Gradual, even tone improvement
Antioxidant Activity: Moderate free radical scavenging
Purity Specifications
Assay: ≥ 99.0%
Loss on Drying: ≤ 0.5%
Residue on Ignition: ≤ 0.1%
Heavy Metals: ≤ 10 ppm
Stability Properties
Shelf Life: 3 years (unopened)
Temperature Stability: Stable up to 80°C
Light Sensitivity: Stable under normal light
pH Stability: Excellent across pH 3-8

Performance Characteristics

Detailed performance metrics demonstrate Alpha Arbutin superiority in cosmetic applications with exceptional skin brightening efficacy, tyrosinase inhibition, and formulation stability across diverse depigmentation products.

Brightening Performance

Efficacy: 0.5-2% for significant skin brightening

Excellent brightening at low concentrations
Tyrosinase Inhibition

IC50: 0.7 μM (superior to kojic acid)

Outstanding enzyme inhibition
Melanin Reduction

Reduction: 30-40% melanin synthesis inhibition

Significant depigmentation activity
Temperature Stability

Working range: Room temp to 80°C stability

Excellent thermal stability
Batch Consistency

Variation: ±1% potency between batches

Exceptional lot-to-lot consistency
Long-term Efficacy

3 years under proper storage conditions

Extended brightening stability

Safety Information

Generally recognized as safe for cosmetic use with excellent skin tolerance. Well-tolerated synthetic alternative to hydroquinone. Handle with standard laboratory precautions including safety goggles and gloves. Patch testing recommended for sensitive skin. Avoid inhalation of dust particles and ensure adequate ventilation during handling.

Generally Safe
Avoid Dust Inhalation
Patch Test Recommended

Storage & Handling

Store in original sealed containers in a cool, dry area away from direct sunlight and moisture. Keep containers tightly closed and protect from extreme temperatures. Use appropriate handling equipment to prevent dust formation and ensure proper ventilation during processing.

Cool, dry storage (15-25°C)
Good ventilation recommended
Original sealed containers
Protect from direct sunlight

Chemical Mechanisms & Reaction Pathways

Alpha-Arbutin demonstrates selective melanin inhibition through competitive tyrosinase inhibition, providing effective skin lightening and hyperpigmentation reduction with superior safety and efficacy compared to other whitening agents.

Tyrosinase Inhibition

Competitive inhibition of tyrosinase enzyme activity

Reduced melanin production pathway
Melanin Synthesis Blocking

Interrupts DOPA oxidation in melanogenesis

Prevents pigment formation
Cellular Uptake

Enhanced penetration through improved stability

Superior bioavailability
Antioxidant Activity

Secondary antioxidant protection against free radicals

Additional skin protection benefits

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global cosmetic market access with complete documentation packages supporting international standards and cosmetic safety regulations.

INCI Compliance

International Nomenclature of Cosmetic Ingredients certification

EU Cosmetic Regulation

European Union cosmetic safety assessment compliance

FDA Cosmetic Standards

United States Food and Drug Administration compliance

Global Acceptance

International cosmetic regulatory harmonization

Safety Documentation

Complete toxicological and safety data packages

Quality Certificates

ISO 22716 cosmetic Good Manufacturing Practices

Technical Support & Value-Added Services

DRAVYOM's cosmetic chemistry team provides comprehensive formulation support, stability testing, and technical services to optimize Alpha-Arbutin performance in your specific cosmetic applications.

Formulation Development
  • Custom formulation optimization
  • Stability testing protocols
  • Compatibility assessments
  • Performance enhancement strategies
Analytical Services
  • Tyrosinase inhibition assays
  • Melanin content analysis
  • Efficacy testing protocols
  • Skin penetration studies
Technical Support
  • Application troubleshooting
  • Processing optimization
  • Quality control guidance
  • Regulatory compliance support
Supply Solutions
  • Flexible packaging options
  • Custom grade development
  • Global distribution network
  • Just-in-time delivery

Environmental Impact & Sustainability

Our Alpha-Arbutin production emphasizes environmental responsibility through sustainable manufacturing practices, green chemistry principles, and comprehensive environmental impact management for cosmetic applications.

Sustainable Synthesis

Environmentally friendly synthetic routes with minimal waste

Water Conservation

Efficient production with water recycling systems

Green Chemistry

Reduced solvent usage and energy-efficient processes

Biodegradability

Complete biodegradation with no environmental persistence

Environmental Certification

ISO 14001 environmental management compliance

Packaging Sustainability

Recyclable packaging materials and reduction initiatives

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art pharmaceutical-grade manufacturing facility employs advanced synthesis technology and continuous monitoring systems to ensure consistent Alpha-Arbutin quality and performance across all production batches.

Synthesis Process

Advanced enzymatic synthesis in controlled clean-room environment

Optimized for maximum purity and efficacy
Quality Testing

Comprehensive testing including purity, activity, and stability

HPLC verification and biological assays
Quality Systems

ISO 9001:2015 quality management with cosmetic GMP compliance

Continuous improvement and validation
Packaging Control

Specialized packaging for light and oxygen protection

Stability preservation and contamination prevention

Market Applications & Performance Data

Comprehensive cosmetic laboratory data demonstrating Alpha-Arbutin effectiveness across diverse formulations with quantified performance metrics and clinical validations.

Skin Lightening Products
Tyrosinase Inhibition: 85% activity reduction Melanin Reduction: 60% decrease in production Clinical Efficacy: 70% improvement in 8 weeks
Anti-aging Formulations
Age Spot Reduction: 50% improvement Skin Tone: 40% enhancement in evenness Antioxidant Activity: 30% free radical protection
Hyperpigmentation Treatment
Dark Spot Reduction: 65% improvement Safety Profile: 98% dermatological tolerance Stability: 24-month shelf life

DRAVYOM Competitive Advantages

Superior Activity

Consistently high tyrosinase inhibition activity with >99% purity

Reliable Supply

Guaranteed availability with strategic inventory management and production scheduling

Formulation Expertise

Dedicated cosmetic chemistry team provides comprehensive whitening formulation support

Quality Assurance

Rigorous testing protocols with comprehensive certificates and efficacy data

Global Compliance

International regulatory compliance with INCI, EU, and FDA cosmetic standards

Partnership Approach

Collaborative development with cosmetic manufacturers and custom lightening solutions