TE Buffer (Tris-EDTA)
Biotechnology Storage Buffer
Nucleic Acid Buffers

TE Buffer (Tris-EDTA)

High-quality TE buffer essential for molecular biology applications. Combines Tris buffering and EDTA chelation for optimal DNA/RNA storage, purification procedures, and nucleic acid stability in research applications.

  • High-Quality Buffer System
  • DNA/RNA Storage
  • Nucleic Acid Stability
  • Metal Chelation
  • Purification Compatible
  • Research Validated
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Technical Specifications

Buffer Name: TE Buffer (Tris-EDTA)
Tris Component: 10 mM Tris-HCl
EDTA Component: 1 mM EDTA
pH: 8.0 ± 0.1
Osmolarity: ~11 mOsm/kg
Ionic Strength: Low (~10 mM)
Buffer Capacity: pH 7.5-8.5
Sterility: Sterile filtered (0.2 μm)
DNase/RNase: None detected
Stability: 2 years at room temperature
Storage Temperature: Room temperature or 4°C
Packaging Options: 100mL, 500mL, 1L, 5L

Applications

DNA Storage
RNA Storage
Plasmid Storage
DNA Dissolution
PCR Template Prep
Educational Research
Molecular Biology
Nucleic Acid Work
Plant DNA Storage
DNA Quantification
Cloning Applications
Quality Control

Industry-Specific Grades

DRAVYOM offers specialized TE buffer grades tailored for specific nucleic acid storage and handling applications, ensuring optimal stability and regulatory compliance across diverse molecular biology requirements.

Research Grade
pH: 8.0 ± 0.1 Tris: 10 mM EDTA: 1 mM Application: General research
Molecular Biology Grade
pH: 8.0 ± 0.05 DNase/RNase: None detected Sterility: Assured Application: Sensitive work
Ultra-Pure Grade
pH: 8.0 ± 0.02 Heavy metals: <5 ppm Endotoxin: <0.1 EU/mL Application: Long-term storage
Diagnostic Grade
pH: 8.0 ± 0.1 (USP) GMP: Compliant Validation: Clinical Application: Diagnostics

Quality Standards

DRAVYOM's TE Buffer is manufactured under stringent quality control protocols, meeting international nucleic acid storage standards including molecular biology specifications and diagnostic requirements. Our buffer production ensures consistent pH performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
Molecular Biology Grade Specifications
pH 8.0 ± 0.1 Verified
DNase/RNase Testing
Ionic Strength Analysis
Sterility Testing
Certificate of Analysis
Temperature-Controlled Storage

Advanced Chemical Properties & Performance

Biotechnology-grade TE Buffer exhibits exceptional properties essential for DNA/RNA storage and dilution applications. Its ultra-pure composition and optimal pH provide stable nucleic acid preservation and consistent performance in demanding molecular biology procedures.

Buffer Composition
Tris-HCl Concentration: 10 mM (1X TE buffer)
EDTA Concentration: 1 mM (1X TE buffer)
pH Target: 8.0 ± 0.1
Buffer Type: Low ionic strength buffer
Physical Properties
Conductivity (1X): 0.5-0.8 mS/cm at 25°C
Osmolality: ~15 mOsm/kg
Ionic Strength: Very low (minimal interference)
pH Buffering Range: 7.5-8.5 (effective range)
Nucleic Acid Protection
DNase Inhibition: EDTA chelates Mg²⁺/Ca²⁺
RNase Inhibition: Partial protection via EDTA
DNA Stability: Long-term storage compatible
pH Maintenance: Prevents pH-induced degradation
Purity Specifications
Heavy Metals: ≤ 1 ppm
DNase Activity: None detected
RNase Activity: None detected
Endotoxin: ≤ 1 EU/mL
Stability Properties
Shelf Life (Powder): 3 years at room temperature
Solution Stability: 1 year at 4°C
Autoclave Stability: Stable to 121°C for 20 minutes
Freeze Storage: Stable at -20°C indefinitely

Performance Characteristics

Detailed performance metrics demonstrate Biotechnology Grade TE Buffer superiority in nucleic acid storage with exceptional preservation capability, pH stability, and reproducibility across diverse molecular biology applications.

DNA Preservation

Integrity maintenance: >95% after 1 year at 4°C

Excellent long-term storage
Nuclease Protection

DNase inhibition: >99% activity reduction

Effective enzyme inactivation
pH Stability

pH drift: <0.1 units over 6 months

Robust buffering capacity
Temperature Tolerance

Storage range: -80°C to +37°C

Wide temperature compatibility
Batch Consistency

pH variation: ±0.05 units between lots

Reliable buffer performance
Solution Clarity

Precipitation: None observed over time

Maintains solution clarity

Safety Information

Generally safe for laboratory use with standard precautions. EDTA may cause mild eye irritation and can chelate essential metals. Handle with standard laboratory protective equipment including gloves and safety goggles. Use good laboratory practices.

Low Toxicity
Eye Protection
Metal Chelator

Storage & Handling

Store powder components at room temperature in dry conditions. Store prepared solutions at 4°C for routine use or -20°C for long-term storage. Autoclaving is recommended for sterile applications. Handle with standard laboratory protective equipment.

Powder: room temperature
Solutions: 4°C or -20°C
Autoclave for sterility
Nuclease-free preparation

Chemical Mechanisms & Reaction Pathways

TE buffer exhibits buffering and chelation properties through Tris base and EDTA action, enabling precise biotechnology applications with predictable reaction pathways and quantitative stoichiometry.

pH Buffering

Tris base maintains physiological pH for nucleic acid stability

Quantitative pH control for biotechnology
Metal Chelation

EDTA sequesters divalent cations preventing nuclease activity

Essential for nucleic acid protection procedures
DNA Stabilization

Combined action preserves nucleic acid integrity

Enables controlled DNA/RNA storage
Enzymatic Protection

Participates in enzyme stabilization and storage

Controlled environment for biotechnology

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global biotechnology laboratory access with complete documentation packages supporting international standards and biotechnology method validations.

Molecular Biology Grade

Ultra-pure specifications for nucleic acid applications

ISO Standards

International standard for buffer specifications and testing

Research Grade

High-purity specifications for DNA/RNA work

REACH Registration

European Union chemical regulation compliance

Method Validation

Supported biotechnology method validation documentation

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's biotechnology team provides comprehensive method support, troubleshooting assistance, and biotechnology services to optimize TE Buffer performance in your specific biotechnology applications.

Method Development
  • Biotechnology method optimization support
  • Buffer preparation protocol guidance
  • DNA/RNA storage optimization validation
  • Custom biotechnology procedures
Biotechnology Services
  • Certificate of Analysis verification
  • Custom purity analysis
  • pH and chelation testing
  • Method validation support
Technical Support
  • Biotechnology troubleshooting consultation
  • Buffer preparation training
  • Nucleic acid storage optimization
  • Laboratory best practices
Supply Solutions
  • Consistent batch scheduling
  • Emergency supply arrangements
  • Custom packaging options
  • Global distribution network

Environmental Impact & Sustainability

Our Biotechnology Grade TE Buffer production emphasizes environmental responsibility through sustainable manufacturing practices, waste minimization, and comprehensive environmental impact management for biotechnology laboratory operations.

Waste Minimization

Optimized formulation with minimal buffer waste generation

Water Treatment

Advanced wastewater treatment and neutralization systems

Clean Production

Energy-efficient preparation with emission controls

Safe Disposal

Comprehensive guidance for buffer waste management

ISO 14001

Environmental management system certified production

Container Recycling

Specialized buffer container recycling programs

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art biotechnology reagent manufacturing facility employs advanced preparation technology and continuous monitoring systems to ensure consistent Biotechnology Grade TE Buffer quality and performance across all production batches.

Production Process

Advanced buffer preparation in sterile controlled environment

Multi-stage filtration for biotechnology grade quality
Quality Testing

20-point biotechnology testing protocol including pH and EDTA analysis

Chelation verification and ion chromatography
Quality Systems

ISO 9001:2015 quality management with biotechnology laboratory accreditation

Continuous improvement and method validation
Packaging Control

Sterile containers with nuclease-free packaging

Stability maintenance and contamination prevention

Market Applications & Performance Data

Comprehensive biotechnology laboratory data demonstrating Biotechnology Grade TE Buffer effectiveness across diverse applications with quantified performance metrics and biotechnology method validations.

Biotechnology Laboratories
Precision: ±0.01 pH units in buffer systems Protection Efficiency: 99.9% nuclease inhibition Method Validation: 100% biotechnology compliance
Research Institutions
Publication Support: 3000+ cited methods Reproducibility: >99% inter-lab agreement Innovation: Custom buffer system development
Quality Control Labs
Reliability: 99.9% batch consistency Audit Success: 100% regulatory compliance Efficiency: 60% improved DNA stability

DRAVYOM Competitive Advantages

Superior Purity

Consistently exceeds biotechnology specifications with exceptional nuclease-free quality and pH stability

Reliable Supply

Guaranteed availability with strategic inventory management and biotechnology-grade production scheduling

Biotechnology Expertise

Dedicated biotechnology team provides method development and troubleshooting support

Quality Assurance

Traceable certificates with comprehensive biotechnology data and method validation support

Global Standards

International compliance with molecular biology and research specifications for worldwide acceptance

Partnership Approach

Collaborative relationships with biotechnology laboratories and custom buffer development services