Potassium Dihydrogen Phosphate
Biotechnology Buffer Component
Buffer Components

Potassium Dihydrogen Phosphate

High-purity potassium dihydrogen phosphate essential for biotechnology applications. Provides critical phosphate buffering for cell culture media, biochemical procedures, and molecular biology techniques requiring precise pH control.

  • High-Purity Buffer Component
  • Phosphate Buffering
  • Cell Culture Compatible
  • pH Control
  • Biochemical Research Grade
  • Laboratory Validated
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Technical Specifications

Chemical Name: Potassium dihydrogen phosphate
CAS Number: 7778-77-0
Molecular Formula: KH2PO4
Molecular Weight: 136.09 g/mol
Physical State: White crystalline powder
Melting Point: 252.6°C
Solubility: Water (227 g/L at 20°C)
pH (1% solution): 4.2-4.6 (Acidic)
Storage Temperature: Room temperature (Keep dry)
Purity: ≥99% (ACS Grade)
Buffer Range: pH 5.8-8.0 (with K2HPO4)
Packaging Options: 100g, 500g, 1kg containers

Applications

Phosphate Buffer Systems
Cell Culture Media
pH Control
Molecular Biology
Biochemical Assays
Educational Research
Protein Studies
Analytical Chemistry
Plant Physiology
Enzyme Studies
Buffer Preparation
Quality Control

Industry-Specific Grades

DRAVYOM offers specialized potassium dihydrogen phosphate grades tailored for specific buffer and cell culture applications, ensuring optimal pH control and regulatory compliance across diverse laboratory applications.

Laboratory Grade
Purity: ≥99% (ACS) Heavy Metals: <5 ppm Insoluble Matter: ≤0.01% Application: General lab use
Cell Culture Grade
Purity: ≥99.5% (ACS) Endotoxin: <1 EU/g pH: 4.2-4.6 Application: Cell culture buffers
Molecular Biology Grade
Purity: ≥99.9% (ACS) DNase/RNase: None detected Protease: None detected Application: Molecular biology
Ultra-Pure Grade
Purity: ≥99.99% (ACS) Trace Metals: <0.5 ppm Organics: <1 ppm Application: Critical applications

Quality Standards

DRAVYOM's Potassium Dihydrogen Phosphate is manufactured under stringent quality control protocols, meeting international laboratory standards including ACS, USP, and cell culture specifications. Our buffer-grade production ensures consistent quality and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
ACS/USP Grade Specifications
≥99% Verified Purity
Buffer Capacity Testing
pH Stability Assessment
Batch-to-Batch Consistency
Certificate of Analysis
Moisture-Protected Storage

Advanced Chemical Properties & Performance

Biotechnology-grade Potassium Dihydrogen Phosphate exhibits exceptional properties essential for buffer systems and molecular biology applications. Its ultra-pure composition ensures reliable performance in demanding biological procedures and research applications.

Chemical Properties
Molecular Weight: 136.09 g/mol
Chemical Formula: KH₂PO₄
Solubility (20°C): 330 g/L in water
pH (0.05 M solution): 4.4-4.7
Physical Properties
Melting Point: 252.6°C
Density: 2.338 g/cm³
Crystal Structure: Tetragonal
Hygroscopicity: Slightly hygroscopic
Buffer Performance
Buffer Range: pH 5.8-8.0 (with K₂HPO₄)
pKa: 7.20 (second dissociation)
Buffer Capacity: Excellent near physiological pH
Ionic Strength: Contributes to solution conductivity
Purity Specifications
Assay (KH₂PO₄): ≥ 99.0%
Heavy Metals (as Pb): ≤ 10 ppm
Chloride (Cl): ≤ 0.001%
Insoluble Matter: ≤ 0.01%
Stability Properties
Shelf Life: 5 years at room temperature
Heat Stability: Stable to 121°C
pH Stability: Stable as solid form
Light Sensitivity: Not light sensitive

Performance Characteristics

Detailed performance metrics demonstrate Biotechnology Grade Potassium Dihydrogen Phosphate superiority in buffer applications with exceptional pH control, precision, and reproducibility across diverse molecular biology procedures.

Buffer Efficiency

pH control: ±0.05 units in phosphate systems

Excellent buffering precision
Solubility Performance

Dissolution: Complete in 1 minute

Rapid buffer preparation
Buffer Capacity

Effective range: pH 6.2-7.8 optimal

Physiological pH maintenance
Temperature Stability

Working range: 4-121°C stable

Wide temperature tolerance
Batch Consistency

Variation: ±0.5% between batches

Reliable analytical performance
Shelf Stability

5 years at room temperature storage

Extended biotechnology grade integrity

Safety Information

Generally considered safe for laboratory use with standard precautions. May cause mild irritation to eyes and respiratory tract if inhaled as dust. Handle with standard laboratory protective equipment including gloves and safety goggles. Ensure proper ventilation during weighing operations.

Low Toxicity
Avoid Dust Inhalation
Eye Protection

Storage & Handling

Store in original sealed containers at room temperature in a dry environment. Keep containers tightly closed and protect from moisture. Use clean, dry spatulas for sampling and ensure containers are resealed immediately after use.

Room temperature storage (15-25°C)
Keep dry environment
Sealed containers only
Clean sampling tools required

Chemical Mechanisms & Reaction Pathways

Potassium dihydrogen phosphate exhibits precise buffering capacity through phosphate equilibrium and ionic strength control, enabling precise biotechnology applications with predictable reaction pathways and quantitative stoichiometry.

Phosphate Buffering

Primary buffer system: KH₂PO₄ ⇌ K⁺ + H₂PO₄⁻ (pKa = 7.2)

Quantitative pH control for biotechnology
Ionic Equilibrium

Optimal ionic strength maintenance for biological systems

Essential for enzyme activity procedures
Enzyme Cofactor

Potassium and phosphate cofactor roles in metabolism

Enables controlled enzymatic reactions
Crystallization

Participates in protein crystallization and precipitation

Controlled environment for biotechnology

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global biotechnology laboratory access with complete documentation packages supporting international standards and biotechnology method validations.

ACS Specifications

American Chemical Society analytical reagent standards compliance

ISO Standards

International standard for buffer salt specifications and testing

Molecular Biology Grade

Ultra-pure specifications for molecular biology applications

REACH Registration

European Union chemical regulation compliance

Method Validation

Supported biotechnology method validation documentation

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's biotechnology team provides comprehensive method support, troubleshooting assistance, and biotechnology services to optimize Potassium Dihydrogen Phosphate performance in your specific biotechnology applications.

Method Development
  • Biotechnology method optimization support
  • Buffer system design guidance
  • pH optimization protocols
  • Custom biotechnology procedures
Biotechnology Services
  • Certificate of Analysis verification
  • Custom purity analysis
  • Buffer capacity testing
  • Method validation support
Technical Support
  • Biotechnology troubleshooting consultation
  • Storage and handling guidance
  • Solution preparation training
  • Laboratory best practices
Supply Solutions
  • Consistent batch scheduling
  • Emergency supply arrangements
  • Custom packaging options
  • Global distribution network

Environmental Impact & Sustainability

Our Biotechnology Grade Potassium Dihydrogen Phosphate production emphasizes environmental responsibility through sustainable manufacturing practices, waste minimization, and comprehensive environmental impact management for biotechnology laboratory operations.

Waste Minimization

Optimized crystallization with minimal waste generation

Water Treatment

Advanced wastewater treatment and recycling systems

Clean Production

Energy-efficient purification with emission controls

Safe Disposal

Comprehensive guidance for buffer solution waste management

ISO 14001

Environmental management system certified production

Container Recycling

Standard container return and recycling programs

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art biotechnology reagent manufacturing facility employs advanced crystallization technology and continuous monitoring systems to ensure consistent Biotechnology Grade Potassium Dihydrogen Phosphate quality and performance across all production batches.

Production Process

Advanced crystallization and purification in controlled environment

Multi-stage purification for biotechnology grade quality
Quality Testing

18-point biotechnology testing protocol including purity and buffer capacity analysis

Ion chromatography verification and pH stability testing
Quality Systems

ISO 9001:2015 quality management with biotechnology laboratory accreditation

Continuous improvement and method validation
Packaging Control

Moisture-resistant containers with protective atmosphere packaging

Stability maintenance and contamination prevention

Market Applications & Performance Data

Comprehensive biotechnology laboratory data demonstrating Biotechnology Grade Potassium Dihydrogen Phosphate effectiveness across diverse applications with quantified performance metrics and biotechnology method validations.

Biotechnology Laboratories
Precision: ±0.01% RSD in buffer preparations Buffer Stability: 99.5% pH maintenance over 72h Method Validation: 100% biotechnology compliance
Research Institutions
Publication Support: 600+ cited methods Reproducibility: >99% inter-lab agreement Innovation: Custom buffer development
Quality Control Labs
Reliability: 99.9% batch consistency Audit Success: 100% regulatory compliance Efficiency: 30% improved buffer stability

DRAVYOM Competitive Advantages

Superior Purity

Consistently exceeds biotechnology specifications with ultra-low impurities and exceptional buffering capacity

Reliable Supply

Guaranteed availability with strategic inventory management and biotechnology-grade production scheduling

Biotechnology Expertise

Dedicated biotechnology team provides method development and troubleshooting support

Quality Assurance

Traceable certificates with comprehensive biotechnology data and method validation support

Global Standards

International compliance with ACS, ISO, and molecular biology specifications for worldwide acceptance

Partnership Approach

Collaborative relationships with biotechnology laboratories and custom buffer development services