Deoxyguanosine Monohydrate
Biotechnology Premium
DNA Building Block

Deoxyguanosine Monohydrate

High-quality Deoxyguanosine Monohydrate for DNA synthesis, molecular biology research, and nucleotide studies. Premium grade deoxyribonucleoside manufactured for biotechnology applications and genetic research.

  • DNA Synthesis Component
  • Deoxyribonucleoside Structure
  • Molecular Biology Compatible
  • Nucleotide Research Grade
  • High Purity Standard
  • Genetic Research Quality
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Technical Specifications

Chemical Name: 2'-Deoxyguanosine monohydrate
CAS Number: 5654-37-5
Molecular Formula: C10H13N5O4·H2O
Molecular Weight: 285.25 g/mol
Physical State: White to off-white crystalline powder
Melting Point: 265°C (decomp.)
Solubility: Water (slightly), DMSO, alkaline solutions
UV Absorption: λmax 252 nm (pH 7)
Storage Temperature: 2-8°C (Protected from light)
Purity: ≥98% (HPLC)
Water Content: 5.5-7.0% (Karl Fischer)
Packaging Options: 1g, 5g, 25g containers

Applications

DNA Synthesis
Nucleotide Research
Biochemical Studies
Molecular Biology
Genetic Research
Educational Research
Cell Biology Studies
Pharmaceutical Research
Plant Genetics
Enzymatic Studies
Structural Biology
Quality Control

Industry-Specific Grades

DRAVYOM offers specialized deoxyguanosine grades tailored for specific nucleotide research and genetic applications, ensuring optimal purity and regulatory compliance across diverse molecular biology applications.

Research Grade
Purity: ≥98% (HPLC) Water Content: 5.5-7.0% Heavy Metals: <10 ppm Application: General research
Molecular Biology Grade
Purity: ≥99% (HPLC) DNase/RNase: None detected Endotoxin: <1 EU/mg Application: DNA synthesis
Analytical Grade
Purity: ≥99.5% (HPLC) Isomers: <0.1% Solvent Residues: <10 ppm Application: Analytical studies
Pharmaceutical Grade
Purity: ≥99.9% (HPLC) USP/EP: Compliant Microbial: Tested Application: Drug development

Quality Standards

DRAVYOM's Deoxyguanosine Monohydrate is manufactured under stringent quality control protocols, meeting international nucleotide standards including USP, ICH, and research specifications. Our nucleotide production ensures consistent purity and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
Nucleotide Grade Specifications
≥98% HPLC Verified Purity
UV Spectroscopy Verification
Nucleotide Integrity Assessment
Stability Testing
Certificate of Analysis
Light-Protected Storage

Advanced Chemical Properties & Performance

Deoxyguanosine Monohydrate exhibits exceptional nucleoside properties essential for molecular biology applications. Its purine structure and DNA building block characteristics ensure reliable performance in demanding nucleic acid synthesis protocols and enzymatic studies.

Nucleoside Properties
Molecular Weight: 285.26 Da (monohydrate)
Base Component: Guanine (purine)
Sugar Component: 2'-Deoxyribose
Glycosidic Bond: β-N9-glycosidic linkage
Physical Properties
Appearance: White crystalline powder
Solubility (25°C): 5.4 g/L in water
UV Absorption: λmax = 253 nm (pH 7)
Molar Extinction: ε253 = 13,700 M⁻¹cm⁻¹
Biochemical Performance
DNA Synthesis: dGTP precursor
Enzyme Substrate: Deoxynucleoside kinases
Base Pairing: Complementary to cytosine
Metabolic Role: Purine salvage pathway
Purity Specifications
Nucleoside Purity: ≥ 99% (HPLC)
Related Nucleosides: ≤ 0.5% each
Water Content: 6.0-8.0% (monohydrate)
Heavy Metals: ≤ 10 ppm
Stability Properties
Shelf Life: 3 years (-20°C, dry)
pH Stability: Stable pH 6-8
Hydrolysis Rate: Slow at neutral pH
Solution Stability: Weeks at 4°C

Performance Characteristics

Detailed performance metrics demonstrate Deoxyguanosine Monohydrate superiority in nucleic acid applications with exceptional substrate activity, solubility, and reproducibility across diverse DNA synthesis protocols and enzymatic studies.

DNA Synthesis

Incorporation efficiency: >95%

Excellent nucleotide building block
Enzyme Substrate

Kinase activity: Km = 5-50 μM

Efficient phosphorylation
Solubility Performance

Water solubility: 5.4 g/L at 25°C

Adequate aqueous dissolution
Temperature Stability

Working range: 4-37°C

Stable across biological temperatures
Batch Reproducibility

Variation: ±1% between batches

Consistent nucleoside quality
Stability Performance

3 years under proper storage

Extended nucleoside integrity

Safety Information

Generally safe naturally occurring nucleoside for research use. Handle with standard laboratory precautions including safety goggles, gloves, and lab coat. Non-toxic and biodegradable. Avoid inhalation of powder and direct contact with eyes. Safe for molecular biology applications.

Naturally Occurring
Biodegradable
Standard Lab Precautions

Storage & Handling

Store in original containers at -20°C in a dry environment. Keep containers tightly closed with desiccant to prevent moisture absorption. Solutions can be stored at 4°C for extended periods when sterile. Maintain crystalline hydrate form.

Frozen storage (-20°C)
Dry environment required
Desiccant required
Maintain hydrate form

Chemical Mechanisms & Reaction Pathways

Deoxyguanosine monohydrate undergoes phosphorylation and incorporation into DNA synthesis pathways, enabling precise nucleotide research applications with predictable base pairing mechanisms and quantitative DNA replication studies.

Phosphorylation

Sequential phosphorylation by deoxyguanosine kinase and nucleotide kinases

Essential for DNA synthesis
Base Pairing

Watson-Crick hydrogen bonding with cytosine residues

Critical for DNA stability
DNA Incorporation

DNA polymerase-mediated incorporation during replication

Enables genetic studies
Hydrate Stability

Crystalline hydrate form for enhanced stability

Supporting nucleotide research

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global molecular biology laboratory access with complete documentation packages supporting international standards and nucleotide research method validations.

Research Grade Standards

High purity specifications for molecular biology applications

ISO Standards

International standard compliance for research reagent specifications

Nucleotide Grade

Nucleotide grade specifications for DNA studies

Global Compliance

International molecular biology research regulation compliance

Method Validation

Supported nucleotide method validation documentation

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's molecular biology team provides comprehensive method support, troubleshooting assistance, and nucleotide services to optimize deoxyguanosine monohydrate performance in your specific research applications.

Method Development
  • DNA synthesis optimization support
  • PCR protocol guidance
  • Nucleotide analysis methods
  • Custom molecular biology procedures
Research Services
  • Certificate of Analysis verification
  • Custom purity analysis
  • Nucleotide activity testing
  • Molecular biology method validation support
Technical Support
  • DNA troubleshooting consultation
  • Storage and handling guidance
  • Laboratory safety protocols
  • Research best practices
Supply Solutions
  • Consistent batch scheduling
  • Emergency supply arrangements
  • Custom packaging options
  • Global distribution network

Environmental Impact & Sustainability

Our deoxyguanosine monohydrate production emphasizes environmental responsibility through sustainable nucleotide synthesis practices, waste minimization, and comprehensive environmental impact management for molecular biology research operations.

Waste Minimization

Optimized nucleotide synthesis with minimal waste generation

Water Treatment

Advanced wastewater treatment and recycling systems

Green Production

Energy-efficient nucleotide synthesis with emission controls

Safe Disposal

Comprehensive guidance for nucleotide waste management

ISO 14001

Environmental management system certified production

Container Recycling

Sustainable container return and recycling programs

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art nucleotide manufacturing facility employs advanced purification technology and continuous monitoring systems to ensure consistent research-grade deoxyguanosine monohydrate quality and performance across all production batches.

Production Process

Advanced nucleotide synthesis and crystallization in controlled environment

Multi-stage purification for research grade quality
Quality Testing

Comprehensive analytical testing including HPLC and mass spectrometry

Chromatographic verification and structural analysis
Quality Systems

ISO 9001:2015 quality management with molecular biology laboratory accreditation

Continuous improvement and method validation
Packaging Control

Moisture-controlled containers with desiccant protection

Hydrate stability protection and contamination prevention

Market Applications & Performance Data

Comprehensive molecular biology research data demonstrating deoxyguanosine monohydrate effectiveness across diverse applications with quantified performance metrics and nucleotide research method validations.

Research Laboratories
Purity: >99% nucleoside content Activity: Confirmed DNA incorporation Stability: 36+ months at -20°C
Academic Institutions
Publication Support: 500+ cited studies Reproducibility: >98% inter-lab agreement Innovation: Custom nucleotide solutions
Biotechnology Companies
Reliability: 99.5% batch consistency Quality Assurance: Validated nucleotide activity Efficiency: Optimized DNA synthesis protocols

DRAVYOM Competitive Advantages

Superior Purity

Consistently exceeds research specifications with ultra-high purity and exceptional nucleotide performance

Reliable Supply

Guaranteed availability with strategic inventory management and research-grade production scheduling

Molecular Biology Expertise

Dedicated molecular biology team provides nucleotide optimization and troubleshooting support

Quality Assurance

Comprehensive certificates with detailed nucleotide performance data and method validation support

Global Standards

International compliance with research specifications for worldwide acceptance

Partnership Approach

Collaborative relationships with research laboratories and custom grade development services