LC-MS Grade Methanol - Analytical Reagent Chemical Structure
Analytical Premium
Analytical Reagent

LC-MS Grade Methanol

Premium LC-MS grade methanol engineered for demanding analytical applications including liquid chromatography-mass spectrometry, analytical chemistry, and research. Our CH₃OH delivers exceptional purity, consistent performance, and reliable supply for critical analytical procedures requiring superior MS compatibility with stringent quality standards.

  • ≥99.95% Purity Guaranteed
  • Superior MS Compatibility
  • Ultra-Low Ion Background
  • Consistent Batch-to-Batch Quality
  • MS Certified Grade
  • Mass Spectrometry Applications
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Technical Specifications

Chemical Formula: CH₃OH
CAS Number: 67-56-1
Purity (Assay): ≥99.95% (LC-MS Grade)
Water Content: ≤0.03%
Metals (ICP): ≤0.1 ppm total
Alkalinity (as NH₃): ≤0.0005%
Acidity (as HCOOH): ≤0.0005%
Residue on Evaporation: ≤0.0003%
Aldehydes (as HCHO): ≤0.0005%
Ion Background: Ultra-low (MS optimized)
MS Performance: Excellent signal-to-noise
Storage Temperature: 15-25°C
Shelf Life: 24 months
Packaging Options: 1L, 4L amber glass bottles

Applications

LC-MS Analysis
Mass Spectrometry
HPLC-MS/MS
UHPLC-MS
Pharmaceutical Analysis
Food & Beverage Testing
Environmental Analysis
Research Applications
Quality Control
Sample Preparation
Reverse Phase LC-MS
Clinical Diagnostics

Industry-Specific Grades

DRAVYOM offers specialized methanol grades tailored for specific mass spectrometry requirements, ensuring optimal performance and regulatory compliance across diverse analytical applications.

LC-MS Grade
Purity: ≥99.95% Ion Background: Ultra-low Metals: ≤0.1 ppm Application: LC-MS systems
MS Grade
Purity: ≥99.98% ESI Compatible: Yes Signal-to-Noise: Optimized Application: Direct MS
Metabolomics Grade
Metabolite: Compatible Extraction: Efficient Background: Minimal Application: Metabolomics
Ultra-Pure Grade
Purity: >99.99% Trace Metals: <0.05 ppm Water: <0.01% Application: Critical MS

Quality Standards

DRAVYOM's LC-MS Grade Methanol is manufactured under stringent quality control protocols, meeting international analytical standards including ACS, ISO, and pharmacopoeia specifications. Our mass spectrometry-grade production ensures consistent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
LC-MS Grade Specifications
≥99.95% Purity Guaranteed
Mass Spectrometry Testing
Superior MS Compatibility
Batch-to-Batch Consistency
Certificate of Analysis
Ultra-Low Ion Background

Advanced Chemical Properties & Performance

AR Grade LC-MS Methanol exhibits exceptional mass spectrometry properties essential for analytical applications. Its ultra-pure composition and minimal ion background ensure reliable performance in demanding LC-MS procedures and analytical determinations.

LC-MS Properties
Ion Background: Ultra-low (<1 ppm ions)
MS Compatibility: ESI, APCI, APPI optimized
Volatility: Excellent for MS interface
Ion Suppression: Minimized contamination
Physical Properties
Appearance: Clear, colorless liquid
Density (20°C): 0.792 g/mL
Viscosity (20°C): 0.59 mPa·s
Boiling Point: 64.7°C
Analytical Performance
Background Noise: Minimal MS interference
Sensitivity: Enhanced signal-to-noise
Ionization Efficiency: Optimized for ESI
System Suitability: Passes all LC-MS tests
Purity Specifications
Chemical Purity: ≥99.9%
Water Content: ≤0.005%
Metal Ions: ≤1 ppm total
Aldehydes: ≤0.0005%
Stability Properties
Shelf Life: 3 years (unopened)
MS Stability: No ion background drift
Oxidation Resistance: Stabilized formulation
Storage Conditions: Cool, dry, inert atmosphere

Performance Characteristics

Detailed performance metrics demonstrate AR Grade LC-MS Methanol superiority in mass spectrometry applications with exceptional ion background control, enhanced ionization efficiency, and reproducibility across diverse LC-MS procedures and testing protocols.

LC-MS Performance

Ionization: Enhanced ESI efficiency

Superior MS compatibility
Ion Background

Contamination: <1 ppm metal ions

Ultra-low interference
Solvent Strength

Elution: Strong polar protic solvent

Excellent separation power
Operating Range

Working range: 5-40°C optimal

Standard LC-MS conditions
Batch Reproducibility

Variation: ±0.005% between batches

Outstanding lot-to-lot consistency
Shelf Stability

3 years under proper storage conditions

Extended LC-MS grade integrity

Safety Information

Highly flammable liquid and vapor. Toxic if swallowed or inhaled. May cause skin and eye irritation. Handle with appropriate protective equipment including gloves, safety goggles, and use in well-ventilated areas. Keep away from heat sources and open flames.

Highly Flammable
Toxic
Irritant

Storage & Handling

Store in original containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers tightly closed and use appropriate flammable solvent storage cabinets. Maintain ultra-clean handling protocols for LC-MS applications.

Cool storage (15-25°C)
Flammable cabinet storage
PTFE-lined containers
Fire suppression system

Chemical Mechanisms & Reaction Pathways

LC-MS Methanol exhibits controlled polar protic interactions and mass spectrometry compatibility through optimized molecular purity, enabling precise analytical applications requiring liquid chromatography-mass spectrometry with enhanced ionization efficiency and minimal matrix effects.

Polar Protic Properties

Hydrogen bonding capability with controlled elution strength for LC-MS applications

Optimized selectivity for pharmaceutical and metabolite separations
MS Compatibility

Low background ions and minimal suppression effects in electrospray ionization

Enhanced sensitivity for bioanalytical applications
Low UV Cutoff

Minimal UV absorption below 205 nm enabling sensitive detection

Superior detection capabilities for drug compounds
Chemical Inertness

Minimal reactivity with analytes and LC-MS system components

Analytical method reproducibility and system longevity
Ultra-Low Residue

Minimal non-volatile residue preventing ion source contamination

Extended MS system performance and maintenance intervals

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global analytical laboratory access with complete documentation packages supporting international standards and LC-MS method validations.

LC-MS Grade Standards

Ultra-high purity specifications for liquid chromatography-mass spectrometry

ISO 6353 Standard

International standard for reagent specifications and testing

USP Grade Available

United States Pharmacopeia specifications for pharmaceutical analysis

REACH Registration

European Union chemical regulation compliance

FDA Method Support

Validated for FDA pharmaceutical LC-MS analytical methods

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's LC-MS team provides comprehensive method support, troubleshooting assistance, and analytical services to optimize LC-MS Methanol performance in your specific mass spectrometry applications.

LC-MS Method Development
  • Mobile phase optimization for MS
  • Ionization enhancement protocols
  • Method validation support
  • Gradient development for bioanalysis
Analytical Services
  • Solvent purity verification
  • MS background analysis
  • Ion suppression studies
  • Water content determination
Custom Solutions
  • Ultra-pure LC-MS grades
  • Custom packaging options
  • Bulk supply solutions
  • Technical troubleshooting

Environmental Impact & Sustainability

DRAVYOM is committed to sustainable LC-MS methanol production and responsible environmental stewardship, implementing advanced technologies and green chemistry principles throughout the manufacturing process.

Production Sustainability
  • High-efficiency distillation technology
  • Heat integration and energy recovery
  • Solvent regeneration and recycling
  • Waste solvent concentration and reuse
  • Carbon footprint minimization
Environmental Protection
  • Advanced VOC emission control
  • Closed-loop water systems
  • Vapor recovery and treatment
  • Groundwater protection measures
  • Environmental management systems
Process Innovation
  • Multi-stage distillation technology
  • Advanced purification systems
  • Energy-efficient concentration methods
  • Waste minimization strategies
  • Green chemistry integration

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art LC-MS methanol facilities employ advanced distillation technology and comprehensive quality assurance systems to ensure consistent, ultra-pure mass spectrometry solvent production.

Advanced Production Technology
  • Multi-column distillation systems
  • Advanced molecular sieve dehydration
  • MS-grade purification processes
  • Automated process control systems
  • Predictive maintenance programs
Quality Control Systems
  • Automated purity analysis (GC-FID)
  • Karl Fischer water determination
  • LC-MS background testing
  • Ion suppression evaluation
  • Statistical process control
Certifications & Standards
  • ISO 9001:2015 Quality Management
  • ISO 14001:2015 Environmental Management
  • OHSAS 18001 Occupational Health & Safety
  • ACS reagent grade certification
  • LC-MS grade compliance

Market Applications & Performance Data

DRAVYOM's LC-MS methanol has proven performance across demanding mass spectrometry applications, with extensive field data demonstrating superior ionization efficiency and consistent analytical results in pharmaceutical and clinical analysis.

LC-MS Performance Data
Ion enhancement: 25% improvement Signal stability: ± 2% RSD Background interference: Minimal
Pharmaceutical Analysis Results
Method precision (RSD): ≤ 0.9% Recovery efficiency: 97-103% Matrix effect: < 4%
Clinical Diagnostic Data
Sensitivity enhancement: 18-fold Quantitation linearity: R² ≥ 0.998 Carryover: < 0.15%

DRAVYOM Competitive Advantages

Choose DRAVYOM for LC-MS methanol solutions that deliver superior performance, reliability, and value. Our commitment to excellence and innovation sets us apart in the mass spectrometry industry.

Exceptional Purity

Consistent ≥99.9% purity with ultra-low background, exceeding ACS specifications for demanding mass spectrometry applications.

Advanced Manufacturing

State-of-the-art distillation technology with multi-stage purification ensuring maximum quality and environmental compliance.

Safety Leadership

Industry-leading safety protocols and handling procedures with comprehensive training programs for solvent management.