LC-MS Grade Acetonitrile - Analytical Reagent Chemical Structure
Analytical Premium
Analytical Reagent

LC-MS Grade Acetonitrile

Premium LC-MS grade acetonitrile engineered for demanding analytical applications including liquid chromatography-mass spectrometry, analytical chemistry, and research. Our CH₃CN delivers exceptional purity, consistent performance, and reliable supply for critical analytical procedures requiring superior MS compatibility with stringent quality standards.

  • ≥99.95% Purity Guaranteed
  • Superior MS Compatibility
  • Ultra-Low Ion Background
  • Consistent Batch-to-Batch Quality
  • MS Certified Grade
  • Mass Spectrometry Applications
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Technical Specifications

Chemical Formula: CH₃CN
CAS Number: 75-05-8
Purity (Assay): ≥99.95% (LC-MS Grade)
Water Content: ≤0.03%
Metals (ICP): ≤0.1 ppm total
Alkalinity (as NH₃): ≤0.0005%
Acidity (as CH₃COOH): ≤0.0005%
Residue on Evaporation: ≤0.0003%
Ion Background: Ultra-low (MS optimized)
MS Performance: Excellent signal-to-noise
Gradient Compatibility: Superior
Storage Temperature: 15-25°C
Shelf Life: 24 months
Packaging Options: 1L, 4L amber glass bottles

Applications

LC-MS Analysis
Mass Spectrometry
HPLC-MS/MS
UHPLC-MS
Pharmaceutical Analysis
Food & Beverage Testing
Environmental Analysis
Research Applications
Quality Control
Sample Preparation
Proteomics
Clinical Diagnostics

Industry-Specific Grades

DRAVYOM offers specialized acetonitrile grades tailored for specific mass spectrometry requirements, ensuring optimal performance and regulatory compliance across diverse analytical applications.

LC-MS Grade
Purity: ≥99.95% Ion Background: Ultra-low Metals: ≤0.1 ppm Application: LC-MS systems
MS Grade
Purity: ≥99.98% ESI Compatible: Yes Signal-to-Noise: Optimized Application: Direct MS
Proteomics Grade
Protein: Compatible Trypsin: Stable Background: Minimal Application: Proteomics
Ultra-Pure Grade
Purity: >99.99% Trace Metals: <0.05 ppm Water: <0.01% Application: Critical MS

Quality Standards

DRAVYOM's LC-MS Grade Acetonitrile is manufactured under stringent quality control protocols, meeting international analytical standards including ACS, ISO, and pharmacopoeia specifications. Our mass spectrometry-grade production ensures consistent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
LC-MS Grade Specifications
≥99.95% Purity Guaranteed
Mass Spectrometry Testing
Superior MS Compatibility
Batch-to-Batch Consistency
Certificate of Analysis
Ultra-Low Ion Background

Advanced Chemical Properties & Performance

AR Grade LC-MS Acetonitrile exhibits exceptional mass spectrometry properties essential for analytical applications. Its ultra-pure composition and minimal ion background ensure reliable performance in demanding LC-MS procedures and analytical determinations.

LC-MS Properties
Ion Background: Ultra-low (<1 ppm ions)
MS Compatibility: ESI, APCI, APPI optimized
Volatility: Excellent for MS interface
Ion Suppression: Minimized contamination
Physical Properties
Appearance: Clear, colorless liquid
Density (20°C): 0.782 g/mL
Viscosity (20°C): 0.34 mPa·s
Boiling Point: 81.6°C
Analytical Performance
Background Noise: Minimal MS interference
Sensitivity: Enhanced signal-to-noise
Peak Shape: Symmetrical chromatography
System Suitability: Passes all LC-MS tests
Purity Specifications
Chemical Purity: ≥99.9%
Water Content: ≤0.005%
Metal Ions: ≤1 ppm total
Non-volatile Matter: ≤0.0005%
Stability Properties
Shelf Life: 3 years (unopened)
MS Stability: No ion background drift
Contamination Resistance: High purity maintenance
Storage Conditions: Cool, dry, inert atmosphere

Performance Characteristics

Detailed performance metrics demonstrate AR Grade LC-MS Acetonitrile superiority in mass spectrometry applications with exceptional ion background control, enhanced sensitivity, and reproducibility across diverse LC-MS procedures and testing protocols.

LC-MS Performance

Sensitivity: Enhanced signal detection

Superior MS compatibility
Ion Background

Contamination: <1 ppm metal ions

Ultra-low interference
Chromatographic Quality

Peak shape: Symmetrical separation

Excellent resolution
Operating Range

Working range: 5-40°C optimal

Standard LC-MS conditions
Batch Reproducibility

Variation: ±0.005% between batches

Outstanding lot-to-lot consistency
Shelf Stability

3 years under proper storage conditions

Extended LC-MS grade integrity

Safety Information

Highly flammable solvent that may cause skin and eye irritation. Handle with appropriate protective equipment including gloves, safety goggles, and use in well-ventilated areas. Keep away from heat sources and open flames. Avoid prolonged inhalation and skin contact.

Highly Flammable
Irritant
Eye Protection

Storage & Handling

Store in original containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers tightly closed and protect from contamination. Use LC-MS grade handling protocols to maintain ultra-low ion background.

Cool storage (15-25°C)
Flammable cabinet storage
PTFE-lined containers
Ultra-clean handling protocols

Chemical Mechanisms & Reaction Pathways

LC-MS Acetonitrile exhibits controlled polar aprotic interactions and mass spectrometry compatibility through optimized molecular purity, enabling precise analytical applications requiring liquid chromatography-mass spectrometry with enhanced ionization efficiency and minimal interference.

Polar Aprotic Properties

High solvating power with controlled elution strength for LC-MS applications

Optimized selectivity for pharmaceutical and metabolite analysis
MS Compatibility

Low background ions and minimal suppression effects in mass spectrometry

Enhanced sensitivity for trace compound detection
Low UV Cutoff

Minimal UV absorption below 190 nm enabling sensitive photodiode array detection

Superior detection capabilities for UV-active compounds
Chemical Inertness

Minimal reactivity with analytes and LC-MS system components

Analytical method reproducibility and system stability
Ultra-Low Residue

Minimal non-volatile residue preventing ion source contamination

Extended MS system performance and sensitivity

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global analytical laboratory access with complete documentation packages supporting international standards and LC-MS method validations.

LC-MS Grade Standards

Ultra-high purity specifications for liquid chromatography-mass spectrometry

ISO 6353 Standard

International standard for reagent specifications and testing

USP Grade Available

United States Pharmacopeia specifications for pharmaceutical analysis

REACH Registration

European Union chemical regulation compliance

FDA Method Support

Validated for FDA pharmaceutical LC-MS analytical methods

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's LC-MS team provides comprehensive method support, troubleshooting assistance, and analytical services to optimize LC-MS Acetonitrile performance in your specific mass spectrometry applications.

LC-MS Method Development
  • Mobile phase optimization for MS
  • Ionization enhancement protocols
  • Method validation support
  • Gradient development for complex samples
Analytical Services
  • Solvent purity verification
  • MS background analysis
  • Ion suppression studies
  • Contamination assessment
Custom Solutions
  • Ultra-pure LC-MS grades
  • Custom packaging options
  • Bulk supply solutions
  • Technical troubleshooting

Environmental Impact & Sustainability

DRAVYOM is committed to sustainable LC-MS acetonitrile production and responsible environmental stewardship, implementing advanced technologies and green chemistry principles throughout the manufacturing process.

Production Sustainability
  • High-efficiency distillation technology
  • Heat integration and energy recovery
  • Solvent regeneration and recycling
  • Waste solvent concentration and reuse
  • Carbon footprint minimization
Environmental Protection
  • Advanced VOC emission control
  • Closed-loop water systems
  • Vapor recovery and treatment
  • Groundwater protection measures
  • Environmental management systems
Process Innovation
  • Multi-stage distillation technology
  • Advanced purification systems
  • Energy-efficient concentration methods
  • Waste minimization strategies
  • Green chemistry integration

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art LC-MS acetonitrile facilities employ advanced distillation technology and comprehensive quality assurance systems to ensure consistent, ultra-pure mass spectrometry solvent production.

Advanced Production Technology
  • Multi-column distillation systems
  • Advanced molecular sieve dehydration
  • MS-grade purification processes
  • Automated process control systems
  • Predictive maintenance programs
Quality Control Systems
  • Automated purity analysis (GC-FID)
  • Karl Fischer water determination
  • LC-MS background testing
  • Ion suppression evaluation
  • Statistical process control
Certifications & Standards
  • ISO 9001:2015 Quality Management
  • ISO 14001:2015 Environmental Management
  • OHSAS 18001 Occupational Health & Safety
  • ACS reagent grade certification
  • LC-MS grade compliance

Market Applications & Performance Data

DRAVYOM's LC-MS acetonitrile has proven performance across demanding mass spectrometry applications, with extensive field data demonstrating superior ionization efficiency and consistent analytical results in pharmaceutical and clinical analysis.

LC-MS Performance Data
Ion suppression: < 3% Signal-to-noise ratio: ≥ 150:1 Background noise: Minimal
Pharmaceutical Analysis Results
Method precision (RSD): ≤ 0.8% Recovery efficiency: 98-102% Matrix effect: < 5%
Clinical Diagnostic Data
Sensitivity enhancement: 20-fold Quantitation linearity: R² ≥ 0.999 Carryover: < 0.1%

DRAVYOM Competitive Advantages

Choose DRAVYOM for LC-MS acetonitrile solutions that deliver superior performance, reliability, and value. Our commitment to excellence and innovation sets us apart in the mass spectrometry industry.

Exceptional Purity

Consistent ≥99.9% purity with ultra-low background, exceeding ACS specifications for demanding mass spectrometry applications.

Advanced Manufacturing

State-of-the-art distillation technology with multi-stage purification ensuring maximum quality and environmental compliance.

Safety Leadership

Industry-leading safety protocols and handling procedures with comprehensive training programs for solvent management.