HPLC Grade Methanol - Analytical Reagent Chemical Structure
Analytical Premium
Analytical Reagent

HPLC Grade Methanol

Premium HPLC grade methanol engineered for demanding analytical applications including high-performance liquid chromatography, analytical chemistry, and research. Our CH₃OH delivers exceptional purity, consistent performance, and reliable supply for critical analytical procedures requiring superior chromatographic properties with stringent ACS quality standards.

  • ≥99.9% Purity Guaranteed
  • Superior HPLC Performance
  • Ultra-Low UV Absorbance
  • Consistent Batch-to-Batch Quality
  • ACS Certified Grade
  • Chromatography Applications
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Technical Specifications

Chemical Formula: CH₃OH
CAS Number: 67-56-1
Purity (Assay): ≥99.9% (HPLC Grade)
Water Content: ≤0.05%
UV Absorbance (280nm): ≤0.01 AU
UV Absorbance (254nm): ≤0.02 AU
UV Absorbance (220nm): ≤0.10 AU
Acidity (as HCOOH): ≤0.001%
Alkalinity (as NH₃): ≤0.001%
Residue on Evaporation: ≤0.0005%
Aldehydes (as HCHO): ≤0.001%
Gradient Performance: Excellent
Storage Temperature: 15-25°C
Packaging Options: 1L, 4L amber glass bottles

Applications

HPLC Mobile Phase
Chromatographic Separation
Analytical Chemistry
LC-MS Applications
Pharmaceutical Analysis
Food & Beverage Testing
Environmental Analysis
Research Applications
Quality Control
Sample Preparation
Reverse Phase HPLC
Clinical Diagnostics

Industry-Specific Grades

DRAVYOM offers specialized methanol grades tailored for specific chromatographic requirements, ensuring optimal performance and regulatory compliance across diverse analytical applications.

HPLC Grade
Purity: ≥99.9% UV Absorbance: <0.01 AU Water: ≤0.05% Application: HPLC analysis
LC-MS Grade
Purity: ≥99.95% Gradient: Optimized Mass Spec: Compatible Application: LC-MS systems
Gradient Grade
Gradient: Superior performance Baseline: Stable Impurities: Ultra-low Application: Gradient elution
ACS Grade
Specification: ACS reagent Assay: ≥99.5% Impurities: Controlled Application: General analytical

Quality Standards

DRAVYOM's HPLC Grade Methanol is manufactured under stringent quality control protocols, meeting international analytical standards including ACS, ISO, and pharmacopoeia specifications. Our chromatography-grade production ensures consistent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
HPLC Grade Specifications
≥99.9% Purity Guaranteed
UV Absorbance Testing
Superior HPLC Performance
Batch-to-Batch Consistency
Certificate of Analysis
Gradient Elution Ready

Advanced Chemical Properties & Performance

AR Grade HPLC Methanol exhibits exceptional chromatographic properties essential for analytical applications. Its ultra-pure composition and optimal solvent characteristics ensure reliable performance in demanding HPLC procedures and analytical determinations.

Chromatographic Properties
UV Cutoff: 205 nm
Gradient Quality: Low baseline drift
Polarity Index: 5.1 (polar protic)
Elution Strength: 0.95 (on silica)
Physical Properties
Appearance: Clear, colorless liquid
Density (20°C): 0.792 g/mL
Viscosity (20°C): 0.59 mPa·s
Refractive Index: 1.329
Analytical Performance
UV Transparency: A ≤0.8 at 254 nm
Gradient Performance: Baseline stability ±0.002 AU
Peak Shape: Symmetrical peaks
System Suitability: Passes all HPLC tests
Purity Specifications
Chemical Purity: ≥99.9%
Water Content: ≤0.02%
Aldehydes: ≤0.001%
Non-volatile Matter: ≤0.001%
Stability Properties
Shelf Life: 3 years (unopened)
Thermal Stability: Stable up to 60°C
Light Stability: Stable under normal light
Storage Conditions: Cool, dry place

Performance Characteristics

Detailed performance metrics demonstrate AR Grade HPLC Methanol superiority in analytical applications with exceptional chromatographic performance, excellent solvent properties, and reproducibility across diverse HPLC procedures and testing protocols.

HPLC Performance

Separation: Excellent peak resolution

Superior chromatographic quality
Solvent Strength

Elution: 0.95 on silica

Strong elution capability
Gradient Quality

Baseline: ±0.002 AU stability

Low drift performance
Temperature Range

Working range: 5-40°C optimal

Standard HPLC conditions
Batch Reproducibility

Variation: ±0.01% between batches

Outstanding lot-to-lot consistency
Shelf Stability

3 years under proper storage conditions

Extended HPLC grade integrity

Safety Information

Highly flammable liquid and vapor. Toxic if swallowed or inhaled. May cause skin and eye irritation. Handle with appropriate protective equipment including gloves, safety goggles, and use in well-ventilated areas. Keep away from heat sources and open flames.

Highly Flammable
Toxic
Irritant

Storage & Handling

Store in original containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers tightly closed and use appropriate flammable solvent storage cabinets. Maintain fire safety equipment nearby.

Cool storage (15-25°C)
Flammable cabinet storage
Glass or PTFE containers
Fire suppression system

Chemical Mechanisms & Reaction Pathways

HPLC Methanol exhibits controlled polar protic interactions and chromatographic selectivity mechanisms through optimized molecular purity, enabling precise analytical applications requiring high-performance liquid chromatography with enhanced separation efficiency.

Polar Protic Properties

Hydrogen bonding capability with controlled elution strength for normal and reversed-phase HPLC

Optimized selectivity for polar compound separation
Gradient Compatibility

Miscible with water and acetonitrile for smooth gradient elution programs

Baseline stability during complex gradient runs
Low UV Cutoff

Minimal UV absorption below 205 nm enabling sensitive UV detection

Enhanced detection sensitivity for analytes
Chemical Inertness

Minimal reactivity with analytes and chromatographic system components

Analytical method reproducibility
Low Residue Content

Minimal non-volatile residue preventing column contamination

Extended column lifetime and performance

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global analytical laboratory access with complete documentation packages supporting international standards and HPLC method validations.

HPLC Grade Standards

High-purity specifications for liquid chromatography applications

ISO 6353 Standard

International standard for reagent specifications and testing

USP Grade Available

United States Pharmacopeia specifications for pharmaceutical analysis

REACH Registration

European Union chemical regulation compliance

EPA Method Support

Validated for EPA environmental HPLC analytical methods

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's chromatography team provides comprehensive HPLC method support, troubleshooting assistance, and analytical services to optimize HPLC Methanol performance in your specific analytical applications.

HPLC Method Development
  • Mobile phase optimization protocols
  • Gradient elution development
  • Selectivity enhancement methods
  • Method validation support
Analytical Services
  • Solvent purity verification
  • Water content determination
  • UV spectral analysis
  • Impurity profiling
Custom Solutions
  • Ultra-pure HPLC grades
  • Custom packaging options
  • Bulk supply solutions
  • Technical troubleshooting

Environmental Impact & Sustainability

DRAVYOM is committed to sustainable HPLC methanol production and responsible environmental stewardship, implementing advanced technologies and green chemistry principles throughout the manufacturing process.

Production Sustainability
  • High-efficiency distillation technology
  • Heat integration and energy recovery
  • Solvent regeneration and recycling
  • Waste solvent concentration and reuse
  • Carbon footprint minimization
Environmental Protection
  • Advanced VOC emission control
  • Closed-loop water systems
  • Vapor recovery and treatment
  • Groundwater protection measures
  • Environmental management systems
Process Innovation
  • Multi-stage distillation technology
  • Advanced purification systems
  • Energy-efficient concentration methods
  • Waste minimization strategies
  • Green chemistry integration

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art HPLC methanol facilities employ advanced distillation technology and comprehensive quality assurance systems to ensure consistent, high-purity chromatography solvent production.

Advanced Production Technology
  • Multi-column distillation systems
  • Advanced molecular sieve dehydration
  • UV-grade purification processes
  • Automated process control systems
  • Predictive maintenance programs
Quality Control Systems
  • Automated purity analysis (GC-FID)
  • Karl Fischer water determination
  • UV absorbance testing (HPLC-grade)
  • Residue on evaporation analysis
  • Statistical process control
Certifications & Standards
  • ISO 9001:2015 Quality Management
  • ISO 14001:2015 Environmental Management
  • OHSAS 18001 Occupational Health & Safety
  • ACS reagent grade certification
  • HPLC gradient grade compliance

Market Applications & Performance Data

DRAVYOM's HPLC methanol has proven performance across demanding chromatographic applications, with extensive field data demonstrating superior separation efficiency and consistent chromatographic results in pharmaceutical and analytical testing.

HPLC Performance Data
UV cutoff wavelength: ≤ 205 nm Gradient compatibility: Excellent Peak tailing factor: ≤ 1.2
Pharmaceutical Analysis Results
Method precision (RSD): ≤ 1.0% Resolution factor: ≥ 2.0 Baseline stability: ± 0.1 mAU
LC-MS Compatibility Data
Ion suppression: < 5% Signal-to-noise ratio: ≥ 100:1 Matrix effect: Minimal interference

DRAVYOM Competitive Advantages

Choose DRAVYOM for HPLC methanol solutions that deliver superior performance, reliability, and value. Our commitment to excellence and innovation sets us apart in the chromatography industry.

Exceptional Purity

Consistent ≥99.9% purity with ultra-low UV absorbance, exceeding ACS specifications for demanding chromatographic applications.

Advanced Manufacturing

State-of-the-art distillation technology with multi-stage purification ensuring maximum quality and environmental compliance.

Safety Leadership

Industry-leading safety protocols and handling procedures with comprehensive training programs for solvent management.