HPLC Grade Acetonitrile (UV-vis) - Analytical Reagent Chemical Structure
Analytical Premium
Analytical Reagent

HPLC Grade Acetonitrile (UV-vis)

Premium HPLC grade acetonitrile engineered for demanding analytical applications including high-performance liquid chromatography, UV-visible spectroscopy, and analytical chemistry. Our CH₃CN delivers exceptional purity, consistent performance, and reliable supply for critical analytical procedures requiring superior chromatographic properties with stringent ACS quality standards.

  • ≥99.9% Purity Guaranteed
  • Superior UV-vis Transparency
  • Ultra-Low UV Absorbance
  • Consistent Batch-to-Batch Quality
  • ACS Certified Grade
  • Spectroscopy Applications
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Technical Specifications

Chemical Formula: CH₃CN
CAS Number: 75-05-8
Purity (Assay): ≥99.9% (HPLC Grade)
Water Content: ≤0.05%
UV Absorbance (340nm): ≤0.01 AU
UV Absorbance (254nm): ≤0.03 AU
UV Absorbance (220nm): ≤0.10 AU
Acidity (as CH₃COOH): ≤0.001%
Alkalinity (as NH₃): ≤0.001%
Residue on Evaporation: ≤0.0005%
Fluorescence Background: Low (HPLC optimized)
Gradient Performance: Excellent
Storage Temperature: 15-25°C
Packaging Options: 1L, 4L amber glass bottles

Applications

HPLC Mobile Phase
UV-vis Spectroscopy
Analytical Chemistry
LC-MS Applications
Pharmaceutical Analysis
Food & Beverage Testing
Environmental Analysis
Research Applications
Quality Control
Sample Preparation
Chromatographic Analysis
Clinical Diagnostics

Industry-Specific Grades

DRAVYOM offers specialized acetonitrile grades tailored for specific chromatographic and spectroscopic requirements, ensuring optimal performance and regulatory compliance across diverse analytical applications.

HPLC Grade
Purity: ≥99.9% UV Absorbance: <0.01 AU Water: ≤0.05% Application: HPLC analysis
LC-MS Grade
Purity: ≥99.95% Gradient: Optimized Mass Spec: Compatible Application: LC-MS systems
Spectrophotometric Grade
UV Transparency: Superior Fluorescence: Minimal Background: Ultra-low Application: UV-vis analysis
ACS Grade
Specification: ACS reagent Assay: ≥99.5% Impurities: Controlled Application: General analytical

Quality Standards

DRAVYOM's HPLC Grade Acetonitrile is manufactured under stringent quality control protocols, meeting international analytical standards including ACS, ISO, and pharmacopoeia specifications. Our chromatography-grade production ensures consistent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
HPLC Grade Specifications
≥99.9% Purity Guaranteed
UV Absorbance Testing
Superior HPLC Performance
Batch-to-Batch Consistency
Certificate of Analysis
UV-vis Compatible

Advanced Chemical Properties & Performance

AR Grade HPLC Acetonitrile UV exhibits exceptional chromatographic properties essential for analytical applications. Its ultra-pure composition and UV transparency ensure reliable performance in demanding HPLC procedures and analytical determinations.

Chromatographic Properties
UV Cutoff: 190 nm
Gradient Quality: Ultra-low baseline drift
Polarity Index: 5.8 (moderately polar)
Elution Strength: 0.65 (on silica)
Physical Properties
Appearance: Clear, colorless liquid
Density (20°C): 0.782 g/mL
Viscosity (20°C): 0.34 mPa·s
Refractive Index: 1.344
Analytical Performance
UV Transparency: A ≤0.05 at 254 nm
Gradient Performance: Baseline stability ±0.001 AU
Peak Tailing: ≤1.05 asymmetry factor
System Suitability: Passes all HPLC tests
Purity Specifications
Chemical Purity: ≥99.9%
Water Content: ≤0.02%
UV-Absorbing Impurities: ≤0.001%
Non-volatile Matter: ≤0.001%
Stability Properties
Shelf Life: 3 years (unopened)
Thermal Stability: Stable up to 80°C
UV Stability: No degradation under UV
Storage Conditions: Cool, dry, dark place

Performance Characteristics

Detailed performance metrics demonstrate AR Grade HPLC Acetonitrile UV superiority in analytical applications with exceptional chromatographic performance, UV transparency, and reproducibility across diverse HPLC procedures and testing protocols.

HPLC Performance

Resolution: Baseline separation achieved

Superior chromatographic quality
UV Performance

Transparency: A ≤0.05 at 254 nm

Exceptional UV clarity
Gradient Quality

Baseline: ±0.001 AU stability

Ultra-low drift performance
Temperature Range

Working range: 5-40°C optimal

Standard HPLC conditions
Batch Reproducibility

Variation: ±0.01% between batches

Outstanding lot-to-lot consistency
Shelf Stability

3 years under proper storage conditions

Extended HPLC grade integrity

Safety Information

Flammable solvent that may cause skin and eye irritation. Handle with appropriate protective equipment including gloves, safety goggles, and use in well-ventilated areas. Keep away from heat sources and open flames. Avoid prolonged inhalation and skin contact.

Flammable
Irritant
Eye Protection

Storage & Handling

Store in original containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers tightly closed and protect from light. Use appropriate solvent storage equipment and fire safety measures.

Cool storage (15-25°C)
Flammable solvent storage
Glass or PTFE containers
Fire safety measures required

Chemical Mechanisms & Reaction Pathways

HPLC Acetonitrile UV-grade exhibits controlled polar interactions and UV transparency mechanisms through optimized molecular purity, enabling precise analytical applications requiring high-performance liquid chromatography and UV-visible spectroscopy procedures.

Solvent Selectivity

Polar aprotic solvent with controlled elution strength for reversed-phase HPLC

Optimized retention time control and peak resolution
UV Transparency

Minimal UV absorption below 190 nm enabling sensitive detection

Enhanced signal-to-noise ratio for UV detection
Gradient Compatibility

Miscible with water and methanol for gradient elution programs

Smooth baseline stability during gradient runs
Low Residue

Minimal non-volatile residue preventing column contamination

Extended column lifetime and performance
Chemical Inertness

Minimal reactivity with analytes and HPLC system components

Analytical method reproducibility

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global analytical laboratory access with complete documentation packages supporting international standards and HPLC method validations.

HPLC Grade Standards

High-purity specifications for liquid chromatography applications

ISO 6353 Standard

International standard for reagent specifications and testing

USP Grade Available

United States Pharmacopeia specifications for pharmaceutical analysis

REACH Registration

European Union chemical regulation compliance

EPA Method Support

Validated for EPA environmental HPLC analytical methods

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's chromatography team provides comprehensive HPLC method support, troubleshooting assistance, and analytical services to optimize HPLC Acetonitrile UV performance in your specific analytical applications.

HPLC Method Development
  • Mobile phase optimization protocols
  • Gradient elution development
  • Peak resolution enhancement
  • Method validation support
Analytical Services
  • Solvent purity verification
  • UV spectral analysis
  • Water content determination
  • Impurity profiling
Custom Solutions
  • Ultra-pure HPLC grades
  • Custom packaging options
  • Bulk supply solutions
  • Technical troubleshooting

Environmental Impact & Sustainability

DRAVYOM is committed to sustainable HPLC acetonitrile production and responsible environmental stewardship, implementing advanced technologies and green chemistry principles throughout the manufacturing process.

Production Sustainability
  • High-efficiency distillation technology
  • Heat integration and energy recovery
  • Solvent regeneration and recycling
  • Waste solvent concentration and reuse
  • Carbon footprint minimization
Environmental Protection
  • Advanced VOC emission control
  • Closed-loop water systems
  • Vapor recovery and treatment
  • Groundwater protection measures
  • Environmental management systems
Process Innovation
  • Multi-stage distillation technology
  • Advanced purification systems
  • Energy-efficient concentration methods
  • Waste minimization strategies
  • Green chemistry integration

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art HPLC acetonitrile facilities employ advanced distillation technology and comprehensive quality assurance systems to ensure consistent, high-purity chromatography solvent production.

Advanced Production Technology
  • Multi-column distillation systems
  • Advanced molecular sieve dehydration
  • UV-grade purification processes
  • Automated process control systems
  • Predictive maintenance programs
Quality Control Systems
  • Automated purity analysis (GC-FID)
  • Karl Fischer water determination
  • UV absorbance testing (HPLC-grade)
  • Gradient performance validation
  • Statistical process control
Certifications & Standards
  • ISO 9001:2015 Quality Management
  • ISO 14001:2015 Environmental Management
  • OHSAS 18001 Occupational Health & Safety
  • ACS reagent grade certification
  • HPLC UV-grade compliance

Market Applications & Performance Data

DRAVYOM's HPLC acetonitrile UV has proven performance across demanding chromatographic applications, with extensive field data demonstrating superior UV transparency and consistent analytical results in pharmaceutical and environmental testing.

HPLC Performance Data
UV cutoff wavelength: ≤ 190 nm Gradient compatibility: Excellent Peak tailing factor: ≤ 1.2
UV Spectroscopy Results
UV transmission: ≥ 99% at 220nm Baseline stability: ± 0.05 AU Noise level: ≤ 0.01 AU
Pharmaceutical Analysis Data
Method precision (RSD): ≤ 1.2% Resolution factor: ≥ 2.0 Detection sensitivity: 10-fold enhanced

DRAVYOM Competitive Advantages

Choose DRAVYOM for HPLC acetonitrile UV solutions that deliver superior performance, reliability, and value. Our commitment to excellence and innovation sets us apart in the chromatography industry.

Exceptional Purity

Consistent ≥99.9% purity with ultra-low UV absorbance, exceeding ACS specifications for demanding chromatographic and UV applications.

Advanced Manufacturing

State-of-the-art distillation technology with multi-stage purification ensuring maximum quality and environmental compliance.

Safety Leadership

Industry-leading safety protocols and handling procedures with comprehensive training programs for solvent management.