Ar Hematoxylin
Analytical Nuclear Stain
Analytical Reagent

Hematoxylin

Analytical Reagent grade Hematoxylin manufactured for nuclear staining, H&E staining, and histopathology applications. Our AR grade nuclear stain provides reliable staining properties for chromosome studies, tissue morphology analysis, and pathological examinations in clinical diagnostics and research applications.

  • Analytical Grade Purity
  • Nuclear Staining
  • H&E Staining
  • Histopathology
  • Clinical Diagnostics
  • Research Laboratory Use
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Technical Specifications

Stain Type: Basic nuclear stain
Active Component: Hematoxylin
Chemical Formula: C₁₆H₁₄O₆
CAS Number: 517-28-2
Molecular Weight: 302.28 g/mol
Concentration: 0.1% w/v in alcohol
pH: 2.0 - 3.0
Physical State: Dark purple solution
Staining Time: 5-15 minutes
Storage Temperature: 15-30°C, protect from light
Shelf Life: 24 months from manufacture
Nuclear Staining: Blue to purple
Mordant Required: Aluminum salts
Packaging: 100ml, 250ml, 500ml bottles

Applications

Nuclear Staining
Histopathology
H&E Staining
Cell Morphology Studies
Clinical Diagnostics
Research Applications
Medical Education
Pathology Laboratories
Tissue Analysis
Quality Control
Cancer Diagnosis
Routine Histology

Industry-Specific Grades

DRAVYOM offers specialized hematoxylin grades tailored for specific histological and diagnostic requirements, ensuring optimal performance and regulatory compliance across diverse laboratory applications.

AR Grade (Analytical Reagent)
Concentration: 0.1% w/v pH: 2.0-3.0 Clarity: Excellent Application: General histological staining
Clinical Grade
USP/EP Compliant Performance: QC validated Nuclear Detail: Superior Application: Clinical diagnostics
Research Grade
High Purity: >99.5% Batch Consistency: Guaranteed Color Intensity: Optimized Application: Advanced research
Progressive Grade
Controlled Staining Time Flexibility: Extended Background: Minimal Application: Precise nuclear staining

Quality Standards

DRAVYOM's AR Grade Hematoxylin is manufactured under stringent quality control protocols, meeting international histological standards including USP, EP, and clinical laboratory specifications. Our analytical-grade production ensures consistent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
Clinical Laboratory Standards
Precise Hematoxylin Concentration
Morphology Validation Testing
Excellent Nuclear Definition
Batch-to-Batch Consistency
Traceable Certificate of Analysis
Light-Protected Logistics

Advanced Chemical Properties & Performance

AR Grade Hematoxylin exhibits exceptional nuclear staining properties essential for histological and cytological examination. Its ultra-pure natural dye composition ensures reliable performance in H&E staining, routine histopathology, and research applications requiring precise nuclear morphology visualization.

Natural Dye Properties
Source: Logwood extract
Active Component: Hematoxylin
Oxidized Form: Hematein (active stain)
Nuclear Affinity: Nucleic acid binding
Physical Properties
Appearance: Dark blue-purple solution
Molecular Weight: 302.28 g/mol
Solubility: Water and ethanol soluble
Working pH: Slightly acidic to neutral
Staining Performance
Nuclear Staining: Deep blue nuclei
Chromatin Detail: High-resolution structure
Staining Time: 3-10 minutes optimal
Mordant Requirement: Aluminum or iron salts
Quality Specifications
Dye Content: ≥90% pure hematoxylin
Mordant Type: Aluminum potassium sulfate
Water Content: ≤5%
Heavy Metals: ≤0.002%
Stability Properties
Shelf Life: 2 years (dry powder)
Solution Stability: 6 months working solution
Ripening Time: Natural oxidation required
Light Sensitivity: Store protected from light

Performance Characteristics

Detailed performance metrics demonstrate AR Grade Hematoxylin superiority in nuclear staining with exceptional chromatin visualization, reliable color intensity, and reproducible results across diverse histopathological and research applications.

Nuclear Definition

Chromatin detail: High-resolution nuclear structure

Exceptional morphological clarity
Color Intensity

Staining: Deep blue nuclear coloration

Consistent color development
H&E Compatibility

Pairing: Perfect with eosin counterstain

Standard histology protocol
Staining Efficiency

Optimal time: 3-10 minutes staining

Flexible timing window
Batch Consistency

Variation: ±2% between batches

Outstanding lot-to-lot reproducibility
Natural Origin

Source: Pure logwood extract

Natural dye reliability

Safety Information

Generally safe natural dye with minimal toxicity. May cause mild eye and skin irritation. Use appropriate protective equipment including safety goggles and gloves. Avoid inhalation of powder and ensure adequate ventilation. Contains aluminum salts as mordant.

Natural Origin
Mild Irritant
Eye Protection Required

Storage & Handling

Store powder in original containers in a cool, dry, dark place away from moisture and light. Prepare working solutions using distilled water and appropriate mordant. Allow natural ripening time for optimal staining performance or use oxidizing agents for rapid maturation.

Cool, dry storage (15-25°C)
Protect from light
Protect from moisture
Allow ripening time

Chemical Mechanisms & Reaction Pathways

Hematoxylin functions through metal-dye complexation mechanisms, enabling selective nuclear staining and chromatin visualization with predictable oxidation pathways for histological and cytological analysis.

Metal Complexation

Hematoxylin forms cationic complexes with aluminum or iron mordants

Essential for nuclear binding and color development
Oxidation Process

Hematoxylin oxidizes to hematein for active staining capability

Blue-purple nuclear staining mechanism
Nuclear Selectivity

Positively charged dye-metal complex binds to negatively charged DNA

Selective chromatin and nuclei visualization
pH-Dependent Color

Color intensity varies with pH and mordant concentration

Optimal staining at slightly alkaline pH

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global histopathology laboratory access with complete documentation packages supporting international tissue staining standards and diagnostic method validations.

CAP Standards

College of American Pathologists histology protocols

CLSI Guidelines

Clinical and Laboratory Standards Institute tissue staining procedures

FDA Compliance

Food and Drug Administration histological staining requirements

REACH Registration

European Union chemical regulation compliance

WHO Standards

World Health Organization pathology guidelines support

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's histopathology team provides comprehensive nuclear staining support, hematoxylin optimization, and tissue processing method development services for diagnostic and research pathology applications.

Staining Protocols
  • H&E staining optimization
  • Nuclear staining enhancement
  • Mordant selection guidance
  • Color intensity standardization
Pathology Services
  • Stain quality verification
  • Nuclear morphology assessment
  • Tissue preparation support
  • Diagnostic accuracy validation
Technical Support
  • Histopathology consultation
  • Staining technique training
  • Quality control protocols
  • Troubleshooting guidance
Supply Solutions
  • Ready-to-use stain formulations
  • Custom concentration preparations
  • Stability-optimized packaging
  • Global pathology supply network

Environmental Impact & Sustainability

Our hematoxylin production emphasizes environmental responsibility through sustainable natural product extraction practices, minimal waste generation, and comprehensive environmental impact management for diagnostic applications.

Sustainable Sourcing

Environmentally responsible logwood extraction and processing

Solvent Recovery

Alcohol recovery programs and organic waste recycling systems

Efficient Production

Optimized natural product purification with minimal environmental impact

Safe Disposal

Comprehensive stain waste disposal and neutralization guidance

ISO 14001

Environmental management system certified production

Container Recycling

Glass container return and recycling programs

Manufacturing Excellence & Quality Control

DRAVYOM's specialized histological stain facility employs advanced natural product processing technology with continuous monitoring systems to ensure consistent hematoxylin quality and nuclear staining performance across all production batches.

Natural Product Processing

Precise hematoxylin extraction and purification from logwood heartwood

Controlled oxidation and crystallization processes
Quality Testing

18-point testing including purity, staining intensity, and nuclear selectivity

Histological verification and morphological assessment
Quality Systems

ISO 9001:2015 quality management with pathology validation

Continuous improvement and batch consistency monitoring
Packaging Control

Light-protected containers with moisture barrier closures

Stability preservation and oxidation prevention

Market Applications & Performance Data

Comprehensive histopathology laboratory data demonstrating hematoxylin effectiveness across diverse nuclear staining applications with quantified performance metrics and diagnostic validations.

Diagnostic Applications
Nuclear Clarity: >98% clear chromatin visualization Color Consistency: Uniform blue-purple nuclear staining Stability: 36+ months shelf life with proper storage
Research Institutions
Publications: 600+ cited histology procedures Reproducibility: >99.6% inter-lab agreement Innovation: Advanced nuclear staining protocols
Pathology Labs
Reliability: 99.9% batch consistency Audit Success: 100% regulatory compliance Efficiency: 20% improved staining protocols

DRAVYOM Competitive Advantages

Superior Nuclear Staining

Consistently clear nuclear morphology with exceptional chromatin detail for accurate histopathological diagnosis

Reliable Supply

Guaranteed availability with strategic inventory management and natural product sourcing scheduling

Pathology Expertise

Dedicated histopathology team provides nuclear staining method development and diagnostic troubleshooting support

Quality Assurance

Traceable certificates with comprehensive staining performance data and pathology validation support

Global Standards

International compliance with CAP, CLSI, and WHO specifications for worldwide pathology acceptance

Partnership Approach

Collaborative relationships with histopathology laboratories and custom nuclear staining method development services