Ar Congo Red
Analytical Histological Stain
Analytical Reagent

Congo Red

Analytical Reagent grade Congo Red manufactured for pH indicator applications, histological staining, and analytical chemistry. Our AR grade dual-purpose stain provides reliable color change properties for amyloid detection, acid-base determinations, and specialized staining procedures in research and diagnostic applications.

  • Analytical Grade Purity
  • pH Indicator
  • Histological Staining
  • Amyloid Detection
  • Diagnostic Use
  • Research Laboratory Use
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Technical Specifications

Chemical Formula: C₃₂H₂₂N₆Na₂O₆S₂
CAS Number: 573-58-0
Molecular Weight: 696.66 g/mol
Physical State: Dark red crystalline powder
pH Transition Range: 3.0 (blue) - 5.2 (red)
pKa Value: 4.0
Solubility in Water: 1.5 g/100ml (25°C)
Melting Point: 360°C (decomposes)
Loss on Drying: ≤ 15.0%
Chloride (Cl): ≤ 0.02%
Sulfate (SO₄): ≤ 0.5%
Heavy Metals (as Pb): ≤ 0.002%
Indicator Sensitivity: Sharp color transition
Storage Conditions: Cool, dry place, protect from light
Packaging Options: 25g, 100g, 500g plastic bottles

Applications

pH Indicator (3.0-5.2)
Acid-Base Titrations
Educational Chemistry Labs
Protein Detection
Histological Staining
Analytical Chemistry
Enzyme Activity Studies
Colorimetric Analysis
Pharmaceutical Testing
Quality Control Testing
Research Applications
Reference Standards

Industry-Specific Grades

DRAVYOM offers specialized Congo Red grades tailored for specific analytical and research requirements, ensuring optimal indicator performance and regulatory compliance across diverse laboratory applications.

AR Grade (Analytical Reagent)
Purity: ≥ 99.0% Heavy Metals: ≤ 0.002% pH Range: 3.0-5.2 Application: General analytical procedures
ACS Grade (Certified)
Purity: ≥ 99.5% Loss on Drying: ≤ 15.0% Chloride: ≤ 0.02% Application: ACS certified analytical work
Biological Grade
Purity: ≥ 99.8% Protein Detection: Optimized Documentation: Complete COA Application: Biological staining
Educational Grade
Purity: ≥ 98.0% Safety: Student-safe formulation Packaging: Small quantities Application: Teaching laboratories

Quality Standards

DRAVYOM's AR Grade Congo Red is manufactured under stringent quality control protocols, meeting international analytical standards including ACS, ISO, and pharmacopoeia specifications. Our analytical-grade production ensures consistent indicator performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
ACS Grade Specifications
Sharp pH Transition (3.0-5.2)
Advanced Purity Testing
Consistent Color Performance
Batch-to-Batch Consistency
Traceable Certificate of Analysis
Light-Protected Storage

Advanced Chemical Properties & Performance

AR Grade Congo Red exhibits exceptional pH indicator properties and amyloid detection capabilities essential for diagnostic applications. Its ultra-pure composition ensures reliable performance in histological staining, amyloidosis diagnosis, and pH indication procedures requiring precise color transitions.

Indicator Properties
pH Range: 3.0 - 5.2
Color Change: Blue-violet to red
Transition: Sharp color change
Amyloid Binding: Specific green birefringence
Physical Properties
Appearance: Dark red powder/solution
Solubility: Water soluble
Molecular Weight: 696.66 g/mol
Light Absorption: λmax ~497 nm
Staining Performance
Amyloid Detection: Apple-green birefringence
Staining Time: 15-30 minutes
Working pH: Alkaline conditions
Sensitivity: High amyloid specificity
Purity Specifications
Dye Content: ≥85% active dye
Water Content: ≤10%
Insoluble Matter: ≤0.1%
Heavy Metals: ≤0.002%
Stability Properties
Shelf Life: 3 years (dry storage)
Light Sensitivity: Store in dark
Solution Stability: 1 month refrigerated
pH Sensitivity: Stable in alkaline pH

Performance Characteristics

Detailed performance metrics demonstrate AR Grade Congo Red superiority in amyloid detection and pH indication with exceptional color transition accuracy, reliable diagnostic results, and reproducible staining across diverse histopathological applications.

Amyloid Specificity

Detection: >98% amyloid specificity

Superior diagnostic accuracy
Color Transition

pH range: Sharp 3.0-5.2 transition

Precise pH indication
Birefringence Quality

Apple-green: High contrast under polarized light

Excellent microscopic visualization
Staining Efficiency

Optimal staining: 15-30 minutes

Efficient diagnostic procedure
Batch Consistency

Variation: ±2% between batches

Outstanding lot-to-lot reproducibility
Solution Stability

Working solution: 1 month stability

Extended working life

Safety Information

Suspected carcinogen - handle with extreme caution. May cause skin and eye irritation. Use appropriate protective equipment including nitrile gloves, safety goggles, and lab coats. Work in well-ventilated areas or fume hood. Avoid skin contact, inhalation, and ingestion.

Suspected Carcinogen
Irritant
Eye Protection Required

Storage & Handling

Store in original containers in a cool, dry, dark place away from incompatible materials. Use only with adequate ventilation and protective equipment. Prepare solutions fresh when possible or store working solutions refrigerated for maximum 1 month. Handle as potential carcinogen.

Cool, dry storage (15-25°C)
Protect from light
Refrigerate working solutions
Adequate ventilation required

Chemical Mechanisms & Reaction Pathways

Congo Red exhibits controlled amyloid binding mechanisms through specific β-pleated sheet interactions, making it suitable for analytical applications requiring amyloid protein detection and histopathological staining procedures.

Amyloid Binding

Selective binding to β-pleated sheet structures in amyloid proteins

Specific protein conformation detection
Birefringence Formation

Apple-green birefringence under polarized light microscopy

Diagnostic optical properties
pH Indicator Properties

Color transition from blue-violet (alkaline) to red (acidic)

pH-dependent color changes
Tissue Penetration

Effective penetration through fixed tissue sections

Histological staining capability
Selective Staining

Differential staining of amyloid vs normal tissue components

Enhanced diagnostic contrast

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global analytical laboratory access with complete documentation packages supporting international standards and analytical method validations.

ACS Specifications

American Chemical Society analytical reagent standards compliance

ISO 6353 Standard

International standard for reagent specifications and testing

USP Grade Available

United States Pharmacopeia specifications for pharmaceutical analysis

REACH Registration

European Union chemical regulation compliance

Histology Standards

Clinical laboratory histopathology method compliance

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's histopathology team provides comprehensive staining method support, troubleshooting assistance, and analytical services to optimize AR Grade Congo Red performance in your specific diagnostic applications.

Staining Method Development
  • Amyloid staining protocol optimization
  • Tissue preparation and fixation guidance
  • Polarized light microscopy techniques
  • Quality control procedures
Analytical Services
  • Certificate of Analysis verification
  • Custom staining intensity testing
  • Birefringence validation
  • Stability assessment
Technical Support
  • Histopathology consultation
  • Safe handling and storage training
  • Method transfer support
  • Laboratory safety protocols
Performance Services
  • Method validation support
  • System suitability testing
  • Stability studies
  • Quality assurance consultation

Environmental Impact & Sustainability

Our AR Grade Congo Red production emphasizes environmental responsibility through sustainable manufacturing practices, controlled azo dye management, and comprehensive environmental impact management for diagnostic laboratory operations.

Azo Dye Safety

Controlled synthesis with safety containment systems

Waste Minimization

Optimized concentrations reducing chemical usage

Clean Production

Energy-efficient synthesis with emission controls

Wastewater Treatment

Advanced treatment of azo dye wastewaters

ISO 14001

Environmental management system certified production

Container Recycling

Glass container return and recycling programs

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art analytical reagent manufacturing facility employs advanced dye synthesis technology with continuous monitoring systems to ensure consistent AR Grade Congo Red quality and performance across all production batches.

Production Process

Controlled synthesis with high-purity aromatic precursors

Precise dye quality and optical properties control
Quality Testing

18-point analytical testing protocol including birefringence and staining specificity

Polarized light verification and performance testing
Quality Systems

ISO 9001:2015 quality management with analytical laboratory accreditation

Continuous improvement and method validation
Packaging Control

Light-resistant containers with controlled atmosphere protection

Dye stability preservation and contamination prevention

Market Applications & Performance Data

Comprehensive diagnostic laboratory data demonstrating AR Grade Congo Red effectiveness across diverse applications with quantified performance metrics and histopathological method validations.

Amyloid Detection
Specificity: >95% for β-pleated sheet structures Sensitivity: Detection limit 10 μg/mL amyloid Birefringence: Apple-green under polarized light
Staining Performance
Color intensity: Consistent red staining Contrast: Clear differentiation from background Penetration: Effective in 4-6 μm tissue sections
pH Indicator Range
Transition: pH 3.0-5.2 (red to blue) Precision: ±0.2 pH units Stability: Maintained over 6-month period
Validation Data
Method validation: Clinical histopathology standards Stability: 24+ months proven shelf life Reproducibility: <3% RSD staining intensity

DRAVYOM Competitive Advantages

Superior Birefringence

Enhanced apple-green birefringence for accurate amyloid detection

Histological Excellence

Optimal tissue penetration and staining specificity

Clinical Standards

Histopathology laboratory compliant with comprehensive documentation

Light-Protected Supply

UV-protected supply chain maintaining optical integrity

Pathology Expertise

Support team with histopathology and amyloid specialists

Safety Management

Controlled azo dye handling with comprehensive safety protocols