AR Grade Acetonitrile
Analytical HPLC Grade
Analytical Reagent

Acetonitrile

Analytical Reagent grade Acetonitrile manufactured for HPLC analysis, chromatography, and analytical chemistry. Our AR grade organic solvent provides reliable chromatographic properties for liquid chromatography, analytical separations, and quality control procedures in research and analytical applications.

  • Analytical Grade Purity
  • HPLC Analysis
  • Chromatography Solvent
  • Analytical Separations
  • Quality Control
  • Research Laboratory Use
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Technical Specifications

Chemical Formula: CH₃CN
CAS Number: 75-05-8
EINECS Number: 200-835-2
Concentration (Assay): ≥99.9% (AR Grade)
Physical State: Clear, colorless liquid
Density (20°C): 0.786 g/cm³
Molecular Weight: 41.05 g/mol
Boiling Point: 81.6°C
Melting Point: -45.7°C
Vapor Pressure (20°C): 73 mmHg
Water Content: ≤ 0.02%
UV Absorbance (280nm): ≤ 0.10
Residue on Evaporation: ≤ 0.003%
Acidity (as CH₃COOH): ≤ 0.003%
Alkalinity (as NH₃): ≤ 0.001%
Acetone & Isopropanol: ≤ 0.01%
UN Number: UN 1648 (Acetonitrile)
Packaging Options: 500ml, 1L, 2.5L amber glass bottles

Applications

HPLC Mobile Phase
LC-MS Analysis
Extraction Solvent
Protein Precipitation
Sample Preparation
Organic Synthesis
Pesticide Analysis
Educational Laboratories
Pharmaceutical Analysis
Quality Control Testing
Electrochemical Studies
Reference Standards

Industry-Specific Grades

DRAVYOM offers specialized acetonitrile grades tailored for specific analytical requirements, ensuring optimal performance and regulatory compliance across diverse laboratory applications.

AR Grade (Analytical Reagent)
Purity: ≥99.9% Water: ≤ 0.02% UV Absorbance: ≤ 0.10 Application: General analytical procedures
HPLC Grade
Purity: ≥99.95% UV Cutoff: 190nm Gradient Grade: Yes Application: HPLC mobile phase
LC-MS Grade
Purity: ≥99.98% Metal Impurities: ≤ 0.1 ppm each Low Background: Yes Application: LC-MS analysis
Ultra-Pure Grade
Purity: ≥99.99% Particle Count: ≤ 10 per mL Trace Organics: ≤ 0.1 ppm Application: Trace analysis

Quality Standards

DRAVYOM's AR Grade Acetonitrile is manufactured under stringent quality control protocols, meeting international analytical standards including ACS, ISO, and pharmacopoeia specifications. Our analytical-grade production ensures consistent solvent performance and regulatory compliance.

ISO 9001:2015 Certified Manufacturing
ACS Grade Specifications
≥99.9% Accurate Purity
Advanced Analytical Testing
Superior Solvent Properties
Batch-to-Batch Consistency
Traceable Certificate of Analysis
Temperature-Controlled Logistics

Advanced Chemical Properties & Performance

AR Grade Acetonitrile exhibits exceptional chemical properties essential for analytical applications. Its ultra-pure composition and precise concentration ensure reliable performance in demanding chromatographic procedures and analytical determinations.

Solvent Properties
Dielectric Constant: 36.2 at 25°C
Dipole Moment: 3.92 D
Polarity Index: 5.8 (moderately polar)
Solubility in Water: Completely miscible
Physical Properties
Boiling Point: 81.6°C
Melting Point: -43.8°C
Vapor Pressure (20°C): 97 mmHg
Refractive Index: 1.3442 at 20°C
Chromatographic Performance
UV Cutoff: 190 nm
Gradient Elution: Excellent compatibility
Peak Symmetry: Tailing factor <1.2
Baseline Stability: ±0.5 mAU drift/hour
Purity Specifications
Water Content: ≤ 0.01%
Acidity (as CH₃COOH): ≤ 0.001%
UV Absorbance (254 nm): ≤ 0.01 AU
Non-volatile Matter: ≤ 0.001%
Stability Properties
Shelf Life: 3 years (unopened)
Light Sensitivity: Store in amber containers
Chemical Stability: Stable under normal conditions
Container Compatibility: Glass, PTFE, PP containers

Performance Characteristics

Detailed performance metrics demonstrate AR Grade Acetonitrile superiority in analytical applications with exceptional solvent purity, chromatographic performance, and reproducibility across diverse analytical procedures and HPLC protocols.

HPLC Performance

UV cutoff: 190 nm for gradient elution

Superior chromatographic resolution
Solvent Miscibility

Complete water miscibility at all ratios

Excellent mobile phase compatibility
UV Transparency

Low UV absorbance: ≤0.01 AU at 254 nm

Minimal baseline interference
Volatility Control

Boiling point: 81.6°C for easy evaporation

Optimal sample preparation
Batch Consistency

Variation: ±0.02% between batches

Outstanding lot-to-lot reproducibility
Shelf Stability

3 years under proper storage conditions

Extended analytical grade integrity

Safety Information

Highly flammable liquid and vapor. May cause eye and skin irritation. Use in well-ventilated areas with appropriate protective equipment including chemical-resistant gloves, safety goggles, and lab coats. Keep away from heat, sparks, and open flames. Ensure proper fire safety measures are in place.

Highly Flammable
Irritant
Inhalation Hazard

Storage & Handling

Store in original amber glass containers in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers tightly closed and use explosion-proof equipment. Ensure proper ventilation and fire suppression systems are in place.

Cool storage (15-25°C)
Fire suppression system required
Amber glass containers only
Explosion-proof ventilation

Chemical Mechanisms & Reaction Pathways

Acetonitrile exhibits versatile chemical properties through polar aprotic solvent mechanisms, making it suitable for analytical chromatography and specialized extraction procedures requiring controlled solvent interactions.

Polar Aprotic Properties

High dielectric constant (38.8) enabling ionic compound dissolution

Optimal for HPLC mobile phases
Nucleophilic Substitution

Promotes SN2 reactions through ionic stabilization

Enhanced analytical reaction kinetics
Extraction Mechanisms

Selective compound extraction based on polarity matching

Precise analytical separations
Chromatographic Behavior

Low viscosity (0.34 cP) providing excellent peak resolution

Superior analytical performance
UV Transparency

Minimal UV absorption allowing sensitive detection

Enhanced analytical sensitivity

Regulatory Compliance & Documentation

Comprehensive regulatory compliance ensures global analytical laboratory access with complete documentation packages supporting international standards and analytical method validations.

ACS Specifications

American Chemical Society analytical reagent standards compliance

ISO 6353 Standard

International standard for reagent specifications and testing

USP Grade Available

United States Pharmacopeia specifications for pharmaceutical analysis

REACH Registration

European Union chemical regulation compliance

EPA Method Support

Validated for EPA environmental analytical methods

SDS Documentation

Multi-language Safety Data Sheets (16 sections, GHS compliant)

Technical Support & Value-Added Services

DRAVYOM's analytical chemistry team provides comprehensive solvent method support, troubleshooting assistance, and analytical services to optimize AR Grade Acetonitrile performance in your specific analytical applications.

Solvent Method Development
  • HPLC mobile phase optimization protocols
  • Extraction method development
  • Gradient elution guidance
  • Water content control optimization
Analytical Services
  • Certificate of Analysis verification
  • Custom purity analysis
  • Water content testing
  • UV absorption validation
Technical Support
  • Chromatographic troubleshooting consultation
  • Safe handling and storage training
  • Method transfer support
  • Laboratory safety protocols
Performance Services
  • Method validation support
  • System suitability testing
  • Stability studies
  • Quality assurance consultation

Environmental Impact & Sustainability

Our AR Grade Acetonitrile production emphasizes environmental responsibility through sustainable manufacturing practices, solvent recovery systems, and comprehensive environmental impact management for analytical laboratory operations.

Solvent Recovery

Spent acetonitrile recovery and purification programs

Emission Control

Advanced vapor recovery systems for minimal environmental impact

Clean Production

Energy-efficient production with emission controls

Safe Disposal

Comprehensive disposal and neutralization guidance

ISO 14001

Environmental management system certified production

Container Recycling

Glass container return and recycling programs

Manufacturing Excellence & Quality Control

DRAVYOM's state-of-the-art analytical reagent manufacturing facility employs advanced distillation technology with continuous monitoring systems to ensure consistent AR Grade Acetonitrile quality and performance across all production batches.

Production Process

Multi-stage distillation with molecular sieve drying

Precise water content control and purification
Quality Testing

18-point analytical testing protocol including water, UV absorption, and residue

GC-MS verification and conductometric analysis
Quality Systems

ISO 9001:2015 quality management with analytical laboratory accreditation

Continuous improvement and method validation
Packaging Control

Amber glass containers with inert atmosphere protection

UV protection and contamination prevention

Market Applications & Performance Data

Comprehensive analytical laboratory data demonstrating AR Grade Acetonitrile effectiveness across diverse applications with quantified performance metrics and analytical method validations.

HPLC Applications
Peak symmetry: >0.95 USP tailing factor UV cutoff: <190 nm for sensitive detection Gradient compatibility: Excellent
Extraction Performance
Recovery rates: >98% for polar compounds Selectivity: High for aromatic compounds Matrix effects: Minimal interference
Spectroscopic Quality
UV transparency: <0.01 AU at 254 nm IR compatibility: Excellent transmission NMR quality: Low water content (<0.01%)
Validation Data
Method validation: USP <621> compliant Stability: 3+ years proven shelf life Reproducibility: <0.02% RSD batch-to-batch

DRAVYOM Competitive Advantages

Ultra-Pure Quality

Water content <0.01%, metals <1 ppm, guaranteed analytical performance

UV Grade Excellence

Exceptional UV transparency for sensitive analytical applications

Multi-Standard Compliance

ACS, USP, and ISO specifications with comprehensive documentation

Reliable Supply Chain

Consistent availability with temperature-controlled logistics

Technical Expertise

Analytical chemistry support team with chromatography specialists

Sustainable Production

Environmentally responsible manufacturing with solvent recovery programs